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In biomedical research, repeated measurements within each subject are often processed to remove artifacts and unwanted sources of variation. The resulting data are used to construct derived outcomes that act as proxies for scientific…

Methodology · Statistics 2026-02-03 Zihang Wang , Razieh Nabi , Benjamin B. Risk

Identifying clinically relevant biomarkers and developing predictive models are central challenges in biomedical research. Biomarkers are commonly used for disease screening, and some provide information not only on the presence or absence…

Methodology · Statistics 2025-08-21 Kazuharu Harada , Shuichi Kawano , Masataka Taguri

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Machine Learning · Computer Science 2026-02-04 Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Heß , Valentyn Melnychuk , Stefan Feuerriegel

Time series anomaly detection is crucial for industrial monitoring services that handle a large volume of data, aiming to ensure reliability and optimize system performance. Existing methods often require extensive labeled resources and…

Machine Learning · Computer Science 2023-07-21 Manqing Dong , Zhanxiang Zhao , Yitong Geng , Wentao Li , Wei Wang , Huai Jiang

In the era of MOOCs, online exams are taken by millions of candidates, where scoring short answers is an integral part. It becomes intractable to evaluate them by human graders. Thus, a generic automated system capable of grading these…

Artificial Intelligence · Computer Science 2020-12-22 Yaman Kumar , Swati Aggarwal , Debanjan Mahata , Rajiv Ratn Shah , Ponnurangam Kumaraguru , Roger Zimmermann

Successful application of machine learning models to real-world prediction problems, e.g. financial forecasting and personalized medicine, has proved to be challenging, because such settings require limiting and quantifying the uncertainty…

Machine Learning · Computer Science 2020-09-15 Yao Zhang , William Zame , Mihaela van der Schaar

Medical datasets are typically affected by issues such as missing values, class imbalance, a heterogeneous feature types, and a high number of features versus a relatively small number of samples, preventing machine learning models from…

Consider the problem of estimating average treatment effects when a large number of covariates are used to adjust for possible confounding through outcome regression and propensity score models. The conventional approach of model building…

Statistics Theory · Mathematics 2018-01-31 Zhiqiang Tan

Medical foundation models show promise to learn broadly generalizable features from large, diverse datasets. This could be the base for reliable cross-modality generalization and rapid adaptation to new, task-specific goals, with only a few…

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Many real-world datasets are labeled with natural orders, i.e., ordinal labels. Ordinal regression is a method to predict ordinal labels that finds a wide range of applications in data-rich domains, such as natural, health and social…

Machine Learning · Computer Science 2020-04-28 Lu Wang , Dongxiao Zhu

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

Ordinal outcomes are common in clinical settings where they often represent increasing levels of disease progression or different levels of functional impairment. Such outcomes can characterize differences in meaningful patient health…

In biomedical studies, researchers are often interested in assessing the association between one or more ordinal explanatory variables and an outcome variable, at the same time adjusting for covariates of any type. The outcome variable may…

Methodology · Statistics 2023-04-17 Kaspar Rufibach

Sequential multiple assignment randomized trials (SMARTs) are used to construct data-driven optimal intervention strategies for subjects based on their intervention and covariate histories in different branches of health and behavioral…

Methodology · Statistics 2022-04-28 Palash Ghosh , Xiaoxi Yan , Bibhas Chakraborty

Computational biomarkers (CBs) are histopathology-derived patterns extracted from hematoxylin-eosin (H&E) whole-slide images (WSIs) using artificial intelligence (AI) to predict therapeutic response or prognosis. Recently, slide-level…

Heart disease continues to pose a critical worldwide health issue, more specifically in areas with insufficient access to healthcare infrastructure and diagnostic systems. Conventional diagnostic approaches often fall short in accurately…

Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 A S M Ahsanul Sarkar Akib , Raduana Khawla , Abdul Hasib

Enhancing the performance of trajectory planners for lane - changing vehicles is one of the key challenges in autonomous driving within human - machine mixed traffic. Most existing studies have not incorporated human drivers' prior…

Robotics · Computer Science 2025-12-23 Cailin Lei , Haiyang Wu , Yuxiong Ji , Xiaoyu Cai , Yuchuan Du

We propose a model-agnostic framework for short-term occupational accident forecasting that leverages safety inspections and models accident occurrences as binary time series. The approach generates daily predictions, which are then…

Machine Learning · Computer Science 2025-12-30 Aho Yapi , Pierre Latouche , Arnaud Guillin , Yan Bailly