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Utilization of liquid fuels is crucial to enabling commercialization of rotating detonation engines in the near future. In this study, Eulerian-Lagrangian simulations are conducted for rotating detonative combustion with dilute n-heptane…

Fluid Dynamics · Physics 2022-02-15 Shan Jin , Chao Xu , Hongtao Zheng , Huangwei Zhang

Quantum chemistry provides accurate and reliable methods to investigate reaction pathways of reactive molecular systems relevant to the interstellar medium. However, the exhaustive exploration of a reactive network is often a daunting task,…

Astrophysics of Galaxies · Physics 2026-02-06 Moritz Bensberg , Silvia Alessandrini , Mattia Melosso , Cristina Puzzarini , Markus Reiher

A wide variety of real life complex networks are prohibitively large for modeling, analysis and control. Understanding the structure and dynamics of such networks entails creating a smaller representative network that preserves its relevant…

Discrete-state, continuous-time Markov models are becoming commonplace in the modelling of biochemical processes. The mathematical formulations that such models lead to are opaque, and, due to their complexity, are often considered…

Quantitative Methods · Quantitative Biology 2017-10-31 Christopher Lester

This paper establishes a data-driven modeling framework for lean Hydrogen (H2)-air reaction rates for the Large Eddy Simulation (LES) of turbulent reactive flows. This is particularly challenging since H2 molecules diffuse much faster than…

Computational Engineering, Finance, and Science · Computer Science 2025-02-19 Quentin Malé , Corentin J Lapeyre , Nicolas Noiray

In the present work, we illustrate the process of constructing a simplified model for complex multi-scale combustion systems. To this end, reduced models of homogeneous ideal gas mixtures of methane and air are first obtained by the novel…

Statistical Mechanics · Physics 2015-05-20 Eliodoro Chiavazzo , Filippo Visconti , Pietro Asinari

This paper analyses of a stochastic model of a chemical reaction network with three types of chemical species ${\cal R}$, ${\cal M}$ and ${\cal U}$ that interact to transform a flow of external resources, the chemical species ${\cal Q}$, to…

Probability · Mathematics 2025-12-01 Vincent Fromion , Philippe Robert , Jana Zaherddine

Permutationally invariant polynomial (PIP) regression has been used to obtain machine-learned (ML) potential energy surfaces, including analytical gradients, for many molecules and chemical reactions. Recently, the approach has been…

Chemical Physics · Physics 2024-07-30 Paul L. Houston , Chen Qu , Apurba Nandi , Riccardo Conte , Qi Yu , Joel M. Bowman

We focus on an efficient approach for quantification of uncertainty in complex chemical reaction networks with a large number of uncertain parameters. Parameter dimension reduction is accomplished by computing an active subspace that…

Chemical Physics · Physics 2019-03-11 M. Vohra , A. Alexanderian , H. Guy , S. Mahadevan

Progress in machine learning has facilitated the development of potentials that offer both the accuracy of first-principles techniques and vast increases in the speed of evaluation. Recently,"$\Delta$-machine learning" has been used to…

Gravitational collapse is one of the most important processes in high-mass star formation. Compared with the classic blue-skewed profiles, redshifted absorption against continuum emission is a more reliable method to detect inward motions…

Astrophysics of Galaxies · Physics 2022-03-02 W. J. Yang , K. M. Menten , A. Y. Yang , F. Wyrowski , Y. Gong , S. P. Ellingsen , C. Henkel , X. Chen , Y. Xu

Understanding grain-surface processes is crucial to interpreting the chemistry of the ISM. However, accurate surface chemistry models are computationally expensive and are difficult to integrate with gas-phase simulations. A new…

Astrophysics · Physics 2009-11-13 R. T. Garrod

The main target of retrosynthesis is to recursively decompose desired molecules into available building blocks. Existing template-based retrosynthesis methods follow a template selection stereotype and suffer from limited training…

Chemical Physics · Physics 2022-12-26 Chaochao Yan , Peilin Zhao , Chan Lu , Yang Yu , Junzhou Huang

Retrosynthesis consists of breaking down a chemical compound recursively step-by-step into molecular precursors until a set of commercially available molecules is found with the goal to provide a synthesis route. Its two primary research…

Artificial Intelligence · Computer Science 2024-03-12 Paula Torren-Peraire , Alan Kai Hassen , Samuel Genheden , Jonas Verhoeven , Djork-Arne Clevert , Mike Preuss , Igor Tetko

Environmental molecular beam experiments are used to examine water interactions with liquid methanol films at temperatures from 170 K to 190 K. We find that water molecules with 0.32 eV incident kinetic energy are efficiently trapped by the…

Hydrogen is vital for sectors like chemicals and others, driven by the need to reduce carbon emissions. Proton Electrolyte Membrane Water Electrolysis (PEMWE) is a key technology for the production of green hydrogen under fluctuating…

Numerical Analysis · Mathematics 2024-10-10 Dayron Chang Dominguez , An Phuc Dam , Thomas Richter , Kai Sundmacher , Shaun M. Alia

We unravel how functional plasticity and redundancy are essential mechanisms underlying the ability to survive of metabolic networks. We perform an exhaustive computational screening of synthetic lethal reaction pairs in Escherichia coli in…

Molecular Networks · Quantitative Biology 2015-06-17 Oriol Güell , Francesc Sagués , M. Ángeles Serrano

Stochastic models for chemical reaction networks have become very popular in recent years. For such models, the estimation of parameter sensitivities is an important and challenging problem. Sensitivity values help in analyzing the network,…

Probability · Mathematics 2013-10-08 Ankit Gupta , Mustafa Khammash

The Chemical Master Equation (CME) provides a highly accurate, yet extremely resource-intensive representation of a stochastic chemical reaction network and its kinetics due to the exponential scaling of its possible states with the number…

Quantum Physics · Physics 2024-04-16 Tilas Kabengele , Yash M. Lokare , J. B. Marston , Brenda M. Rubenstein

$\textit{In situ}$ environmental transmission electron microscopy (ETEM) is a powerful tool for observing structural modifications taking place in heterogeneous catalysts under reaction conditions. However, to strengthen the link between…

Materials Science · Physics 2021-03-19 Joshua L. Vincent , Jarod W. Vance , Jayse T. Langdon , Benjamin K. Miller , Peter A. Crozier