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We propose a Noise Entangled GAN (NE-GAN) for simulating low-dose computed tomography (CT) images from a higher dose CT image. First, we present two schemes to generate a clean CT image and a noise image from the high-dose CT image. Then,…
Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…
We investigate subset-based optimization methods for positron emission tomography (PET) image reconstruction incorporating a regularizing prior. PET reconstruction methods that use a prior, such as the relative difference prior (RDP), are…
In minimally-invasive brain surgeries with indirect and narrow operating environments, 3D brain reconstruction is crucial. However, as requirements of accuracy for some new minimally-invasive surgeries (such as brain-computer interface…
Medical Image-to-image translation is a key task in computer vision and generative artificial intelligence, and it is highly applicable to medical image analysis. GAN-based methods are the mainstream image translation methods, but they…
Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…
Multiphase contrast-enhanced computed tomography (CECT) scan is clinically significant to demonstrate the anatomy at different phases. In practice, such a multiphase CECT scan inherently takes longer time and deposits much more radiation…
Positron emission tomography (PET) reconstruction is a critical challenge in molecular imaging, often hampered by noise amplification, structural blurring, and detail loss due to sparse sampling and the ill-posed nature of inverse problems.…
Positron Emission Tomography (PET) is an imaging method that can assess physiological function rather than structural disturbances by measuring cerebral perfusion or glucose consumption. However, this imaging technique relies on injection…
Recently, paired (e.g. Pix2pix) and unpaired (e.g. CycleGAN) image-to-image translation methods have shown effective in medical imaging tasks. In practice, however, it can be difficult to apply these deep models on medical data volumes,…
Although supervised convolutional neural networks (CNNs) often outperform conventional alternatives for denoising positron emission tomography (PET) images, they require many low- and high-quality reference PET image pairs. Herein, we…
Patlak model is widely used in 18F-FDG dynamic positron emission tomography (PET) imaging, where the estimated parametric images reveal important biochemical and physiology information. Because of better noise modeling and more information…
Deep learning based PET image reconstruction methods have achieved promising results recently. However, most of these methods follow a supervised learning paradigm, which rely heavily on the availability of high-quality training labels. In…
As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…
Fusing multi-modality medical images, such as MR and PET, can provide various anatomical or functional information about human body. But PET data is always unavailable due to different reasons such as cost, radiation, or other limitations.…
Parametric imaging is a compartmental approach that processes nuclear imaging data to estimate the spatial distribution of the kinetic parameters governing tracer flow. The present paper proposes a novel and efficient computational method…
The Computed Tomography (CT) for diagnosis of lesions in human internal organs is one of the most fundamental topics in medical imaging. Low-dose CT, which offers reduced radiation exposure, is preferred over standard-dose CT, and therefore…
Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…
Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…
Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…