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Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Low-count PET is an efficient way to reduce radiation exposure and acquisition time, but the reconstructed images often suffer from low signal-to-noise ratio (SNR), thus affecting diagnosis and other downstream tasks. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Bo Zhou , Huidong Xie , Qiong Liu , Xiongchao Chen , Xueqi Guo , Zhicheng Feng , Jun Hou , S. Kevin Zhou , Biao Li , Axel Rominger , Kuangyu Shi , James S. Duncan , Chi Liu

Background and Objective. Research in the cross-modal medical image translation domain has been very productive over the past few years in tackling the scarce availability of large curated multimodality datasets with the promising…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Daria Zotova , Nicolas Pinon , Robin Trombetta , Romain Bouet , Julien Jung , Carole Lartizien

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

Despite its tremendous value for the diagnosis, treatment monitoring and surveillance of children with cancer, whole body staging with positron emission tomography (PET) is time consuming and associated with considerable radiation exposure.…

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

Signal Processing · Electrical Eng. & Systems 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

MRI and PET are crucial diagnostic tools for brain diseases, as they provide complementary information on brain structure and function. However, PET scanning is costly and involves radioactive exposure, resulting in a lack of PET. Moreover,…

Generating positron emission tomography (PET) images from computed tomography (CT) scans via deep learning offers a promising pathway to reduce radiation exposure and costs associated with PET imaging, improving patient care and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Valerio Guarrasi , Francesco Di Feola , Rebecca Restivo , Lorenzo Tronchin , Paolo Soda

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

Low-dose CT (LDCT) is capable of reducing X-ray radiation exposure, but it will potentially degrade image quality, even yields metal artifacts at the case of metallic implants. For simultaneous LDCT reconstruction and metal artifact…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Baoshun Shi , Bing Chen , Shaolei Zhang , Huazhu Fu , Zhanli Hu

Positron Emission Tomography (PET) /Computed Tomography (CT) is crucial for diagnosing, managing, and planning treatment for various cancers. Developing reliable deep learning models for the segmentation of tumor lesions in PET/CT scans in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Tanya Chutani , Saikiran Bonthu , Pranab Samanta , Nitin Singhal

Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps (u-map) for PET attenuation correction significantly…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Bo Zhou , Jun Hou , Tianqi Chen , Yinchi Zhou , Xiongchao Chen , Huidong Xie , Qiong Liu , Xueqi Guo , Yu-Jung Tsai , Vladimir Y. Panin , Takuya Toyonaga , James S. Duncan , Chi Liu

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Purpose: Neural network image reconstruction directly from measurement data is a relatively new field of research, that until now has been limited to producing small single-slice images (e.g., 1x128x128). This paper proposes a novel and…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 William Whiteley , Wing K. Luk , Jens Gregor

Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…

Medical Physics · Physics 2023-08-08 Fumio Hashimoto , Yuya Onishi , Kibo Ote , Hideaki Tashima , Taiga Yamaya

This paper evaluates the performance of supervised and unsupervised deep learning models for denoising positron emission tomography (PET) images in the presence of reduced acquisition times. Our experiments consider 212 studies (56908…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Ivan Kruzhilov , Stepan Kudin , Luka Vetoshkin , Elena Sokolova , Vladimir Kokh

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However, this extended angle…