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Accurate HIV incidence estimation based on individual recent infection status (recent vs long-term infection) is important for monitoring the epidemic, targeting interventions to those at greatest risk of new infection, and evaluating…

Methodology · Statistics 2021-04-13 Ben Sheng , Changcheng Li , Le Bao , Runze Li

Estimating new HIV infections is significant yet challenging due to the difficulty in distinguishing between recent and long-term infections. We demonstrate that HIV recency status (recent v.s. long-term) could be determined from the…

Applications · Statistics 2024-11-13 Wenlong Yang , Danping Liu , Le Bao , Runze Li

Frequently, empirical studies are plagued with missing data. When the data are missing not at random, the parameter of interest is not identifiable in general. Without additional assumptions, we can derive bounds of the parameters of…

Methodology · Statistics 2018-09-12 Zhichao Jiang , Peng Ding

Understanding historical trends in the epidemic of HIV is important for assessing current and projecting future trends in prevalence, incidence and mortality and for evaluating the impact and cost-effectiveness of control measures. In…

Quantitative Methods · Quantitative Biology 2014-12-10 Brian G. Williams

The Sustainable Development Goals (SDGs) of the United Nations provide a blueprint of a better future by 'leaving no one behind', and, to achieve the SDGs by 2030, poor countries require immense volumes of development aid. In this paper, we…

Machine Learning · Statistics 2024-06-18 Milan Kuzmanovic , Dennis Frauen , Tobias Hatt , Stefan Feuerriegel

In low- and middle-income countries, household surveys are the most reliable data source to examine health and demographic indicators at the subnational level, an exercise in small area estimation. Model-based unit-level models are favored…

Methodology · Statistics 2022-09-23 Yunhan Wu , Jon Wakefield

Key populations at high risk of HIV infection are critical for understanding and monitoring HIV epidemics, but global estimation is hampered by sparse, uneven data. We analyze data from 199 countries for female sex workers (FSW), men who…

Applications · Statistics 2025-09-16 Jiahao Zhang , Keith Sabin , Le Bao

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

Applications · Statistics 2020-09-03 Zhou Lan , Le Bao

Like many chronic diseases, human immunodeficiency virus (HIV) is managed over time at regular clinic visits. At each visit, patient features are assessed, treatments are prescribed, and a subsequent visit is scheduled. There is a need for…

Methodology · Statistics 2024-10-31 Arman Oganisian , Joseph Hogan , Edwin Sang , Allison DeLong , Ben Mosong , Hamish Fraser , Ann Mwangi

Small area estimation (SAE) entails estimating characteristics of interest for domains, often geographical areas, in which there may be few or no samples available. SAE has a long history and a wide variety of methods have been suggested,…

Applications · Statistics 2020-06-19 Jon Wakefield , Taylor Okonek , Jon Pedersen

Female sex workers(FSWs) are one of the most vulnerable and stigmatized groups in society. As a result, they often suffer from a lack of quality access to care. Grassroot organizations engaged in improving health services are often faced…

Machine Learning · Computer Science 2020-12-04 Raghav Awasthi , Prachi Patel , Vineet Joshi , Shama Karkal , Tavpritesh Sethi

Evaluation of HIV large scale interventions programme is becoming increasingly important, but impact estimates frequently hinge on knowledge of changes in behaviour such as the frequency of condom use (CU) over time, or other self-reported…

Pathogen deep-sequencing is an increasingly routinely used technology in infectious disease surveillance. We present a semi-parametric Bayesian Poisson model to exploit these emerging data for inferring infectious disease transmission flows…

Applications · Statistics 2022-01-06 Xiaoyue Xi , Simon EF Spencer , Matthew Hall , M Kate Grabowski , Joseph Kagaayi , Oliver Ratmann

We present a comprehensive statistical methodological framework for estimating contextual exposure to HIV that includes local (grid-cell level) estimation of HIV prevalence and human activity space estimation based on GPS data. The…

With a 676% growth rate in HIV incidence between 2010 and 2021, the HIV/AIDS epidemic in the Philippines is the one that is spreading the quickest in the western Pacific. Although the full effects of COVID-19 on HIV services and development…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Sales G. Aribe , Bobby D. Gerardo , Ruji P. Medina

With the advent of effective pre-exposure prophylaxis agents, active-controlled HIV prevention trials have become a common study design. Nevertheless, estimating absolute efficacy relative to a placebo remains important. In this paper, we…

An increasing amount of geo-referenced mobile phone data enables the identification of behavioral patterns, habits and movements of people. With this data, we can extract the knowledge potentially useful for many applications including the…

Applications · Statistics 2015-03-24 Sanja Brdar , Katarina Gavric , Dubravko Culibrk , Vladimir Crnojevic

We introduce a new version of forward stepwise regression. Our modification finds solutions to regression problems where the selected predictors appear in a structured pattern, with respect to a predefined distance measure over the…

Methodology · Statistics 2011-08-02 Daniel Percival , Kathryn Roeder , Roni Rosenfeld , Larry Wasserman

UNAIDS has embraced an ambitious global target for the implementation of treatment for people living with HIV. This 90-90-90 target would mean that, by 2020, 90% of all those living with HIV should know their status, 90% of these would be…

Quantitative Methods · Quantitative Biology 2014-07-30 Brian Gerard Williams

There are limited options to estimate the treatment effects of variables which are continuous and measured at multiple time points, particularly if the true dose-response curve should be estimated as closely as possible. However, these…

Methodology · Statistics 2024-10-11 Michael Schomaker , Helen McIlleron , Paolo Denti , Iván Díaz
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