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Related papers: Segmentation by Test-Time Optimization (TTO) for C…

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Performance of convolutional neural networks (CNNs) in image analysis tasks is often marred in the presence of acquisition-related distribution shifts between training and test images. Recently, it has been proposed to tackle this problem…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Neerav Karani , Georg Brunner , Ertunc Erdil , Simin Fei , Kerem Tezcan , Krishna Chaitanya , Ender Konukoglu

Purpose: Segmentation of organs-at-risk (OARs) is a bottleneck in current radiation oncology pipelines and is often time consuming and labor intensive. In this paper, we propose an atlas-based semi-supervised registration algorithm to…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Charles Huang , Masoud Badiei , Hyunseok Seo , Ming Ma , Xiaokun Liang , Dante Capaldi , Michael Gensheimer , Lei Xing

Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Neerav Karani , Ertunc Erdil , Krishna Chaitanya , Ender Konukoglu

Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…

Quantitative Methods · Quantitative Biology 2023-05-15 Mobina Naeemi , Mohamad Reza Esmaeili , Iraj Abedi

Objective: Spatiotemporal optimization in radiation therapy involves determining the optimal number of dose delivery fractions (temporal) and the optimal dose per fraction (spatial). Traditional approaches focus on maximizing the…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Wangyao Li , Ronald C Chen , Hao Gao

Tumor segmentation is a fundamental step for radiotherapy treatment planning. To define an accurate segmentation of the primary tumor (GTVp) of oropharyngeal cancer patients (OPC), simultaneous assessment of different image modalities is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Alessia De Biase , Nanna Maria Sijtsema , Lisanne van Dijk , Johannes A. Langendijk , Peter van Ooijen

Lack of large expert annotated MR datasets makes training deep learning models difficult. Therefore, a cross-modality (MR-CT) deep learning segmentation approach that augments training data using pseudo MR images produced by transforming…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Jue Jiang , Yu-Chi Hu , Neelam Tyagi , Pengpeng Zhang , Andreas Rimner , Joseph O. Deasy , Harini Veeraraghavan

Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However,…

In order to optimize the radiotherapy delivery for cancer treatment, especially when dealing with complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), the accurate contouring of the Planning Target Volume (PTV) is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ricardo Coimbra Brioso , Damiano Dei , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Automatic segmentation of organs-at-risk (OAR) in computed tomography (CT) is an essential part of planning effective treatment strategies to combat lung and esophageal cancer. Accurate segmentation of organs surrounding tumours helps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Sulaiman Vesal , Nishant Ravikumar , Andreas Maier

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

We consider the problem of improving the human instance segmentation mask quality for a given test image using keypoints estimation. We compare two alternative approaches. The first approach is a test-time adaptation (TTA) method, where we…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Kambiz Azarian , Debasmit Das , Hyojin Park , Fatih Porikli

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan

The delineation of tumor target and organs-at-risk is critical in the radiotherapy treatment planning. Automatic segmentation can be used to reduce the physician workload and improve the consistency. However, the quality assurance of the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Yihao Zhao , Cuiyun Yuan , Ying Liang , Yang Li , Chunxia Li , Man Zhao , Jun Hu , Wei Liu , Chenbin Liu

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

Medical Physics · Physics 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Despite the widespread availability of in-treatment room cone beam computed tomography (CBCT) imaging, due to the lack of reliable segmentation methods, CBCT is only used for gross set up corrections in lung radiotherapies. Accurate and…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Jue Jiang , Sadegh Riyahi Alam , Ishita Chen , Perry Zhang , Andreas Rimner , Joseph O. Deasy , Harini Veeraraghavan

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain…

Computer Vision and Pattern Recognition · Computer Science 2018-08-17 Mikael Agn , Per Munck af Rosenschöld , Oula Puonti , Michael J. Lundemann , Laura Mancini , Anastasia Papadaki , Steffi Thust , John Ashburner , Ian Law , Koen Van Leemput

Background: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation in MR-guided adaptive radiotherapy (MRgART). This study trained and evaluated a deep learning DIR method for domain invariant…

In radiotherapy, the internal movement of organs between treatment sessions causes errors in the final radiation dose delivery. Motion models can be used to simulate motion patterns and assess anatomical robustness before delivery.…