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Registration-based atlas building often poses computational challenges in high-dimensional image spaces. In this paper, we introduce a novel hybrid atlas building algorithm that fast estimates atlas from large-scale image datasets with much…

Computer Vision and Pattern Recognition · Computer Science 2022-02-15 Nian Wu , Jian Wang , Miaomiao Zhang , Guixu Zhang , Yaxin Peng , Chaomin Shen

Atlas construction is fundamental to medical image analysis, offering a standardized spatial reference for tasks such as population-level anatomical modeling. While data-driven registration methods have recently shown promise in pairwise…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Ziwei Zou , Bei Zou , Xiaoyan Kui , Wenqi Lu , Haoran Dou , Arezoo Zakeri , Timothy Cootes , Alejandro F Frangi , Jinming Duan

Joint registration of a stack of 2D histological sections to recover 3D structure (``3D histology reconstruction'') finds application in areas such as atlas building and validation of \emph{in vivo} imaging. Straightforward pairwise…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Adrià Casamitjana , Marco Lorenzi , Sebastiano Ferraris , Loc Peter , Marc Modat , Allison Stevens , Bruce Fischl , Tom Vercauteren , Juan Eugenio Iglesias

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Deep learning models for semantic segmentation are able to learn powerful representations for pixel-wise predictions, but are sensitive to noise at test time and do not guarantee a plausible topology. Image registration models on the other…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Matthew Sinclair , Andreas Schuh , Karl Hahn , Kersten Petersen , Ying Bai , James Batten , Michiel Schaap , Ben Glocker

Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Hessam Sokooti , Marius Staring , Ivana Isgum

We present a method for fast biomedical image atlas construction using neural fields. Atlases are key to biomedical image analysis tasks, yet conventional and deep network estimation methods remain time-intensive. In this preliminary work,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Zeen Chi , Zhongxiao Cong , Clinton J. Wang , Yingcheng Liu , Esra Abaci Turk , P. Ellen Grant , S. Mazdak Abulnaga , Polina Golland , Neel Dey

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

In medical image analysis, constructing an atlas, i.e. a mean representative of an ensemble of images, is a critical task for practitioners to estimate variability of shapes inside a population, and to characterise and understand how…

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Limited capture range, and the requirement to provide high quality initialization for optimization-based 2D/3D image registration methods, can significantly degrade the performance of 3D image reconstruction and motion compensation…

Computer Vision and Pattern Recognition · Computer Science 2018-01-24 Benjamin Hou , Bishesh Khanal , Amir Alansary , Steven McDonagh , Alice Davidson , Mary Rutherford , Jo V. Hajnal , Daniel Rueckert , Ben Glocker , Bernhard Kainz

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo

We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

Nonlinear registration of 2D histological sections with corresponding slices of MRI data is a critical step of 3D histology reconstruction. This task is difficult due to the large differences in image contrast and resolution, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Juan Eugenio Iglesias , Marc Modat , Loic Peter , Allison Stevens , Roberto Annunziata , Tom Vercauteren , Ed Lein , Bruce Fischl , Sebastien Ourselin
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