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The potential of Reinforcement Learning (RL) has been demonstrated through successful applications to games such as Go and Atari. However, while it is straightforward to evaluate the performance of an RL algorithm in a game setting by…

Machine Learning · Computer Science 2020-08-28 MingYu Lu , Zachary Shahn , Daby Sow , Finale Doshi-Velez , Li-wei H. Lehman

In this article, we propose a novel algorithm for deep reinforcement learning named Expert Q-learning. Expert Q-learning is inspired by Dueling Q-learning and aims at incorporating semi-supervised learning into reinforcement learning…

Machine Learning · Computer Science 2024-06-26 Li Meng , Anis Yazidi , Morten Goodwin , Paal Engelstad

With the advancement in drug development, multiple treatments are available for a single disease. Patients can often benefit from taking multiple treatments simultaneously. For example, patients in Clinical Practice Research Datalink (CPRD)…

Applications · Statistics 2018-04-17 Muxuan Liang , Ye Ting , Haoda Fu

In both the fields of computer science and medicine there is very strong interest in developing personalized treatment policies for patients who have variable responses to treatments. In particular, I aim to find an optimal personalized…

Machine Learning · Computer Science 2014-07-01 Yousuf M. Soliman

We present a framework, which we call Molecule Deep $Q$-Networks (MolDQN), for molecule optimization by combining domain knowledge of chemistry and state-of-the-art reinforcement learning techniques (double $Q$-learning and randomized value…

Machine Learning · Computer Science 2020-06-22 Zhenpeng Zhou , Steven Kearnes , Li Li , Richard N. Zare , Patrick Riley

We study the inverse optimal control problem in social sciences: we aim at learning a user's true cost function from the observed temporal behavior. In contrast to traditional phenomenological works that aim to learn a generative model to…

Machine Learning · Computer Science 2018-05-23 Yichen Wang , Le Song , Hongyuan Zha

The increasing penetration of DER with smart-inverter functionality is set to transform the electrical distribution network from a passive system, with fixed injection/consumption, to an active network with hundreds of distributed…

The growing threat of low-cost kamikaze drone swarms poses a critical challenge to modern defense systems demanding rapid and strategic decision-making to prioritize interceptions across multiple effectors and high-value target zones. In…

Machine Learning · Computer Science 2025-09-23 Alessandro Palmas

It is common practice in deep learning to use overparameterized networks and train for as long as possible; there are numerous studies that show, both theoretically and empirically, that such practices surprisingly do not unduly harm the…

Machine Learning · Computer Science 2020-03-05 Leslie Rice , Eric Wong , J. Zico Kolter

The transfer of knowledge from one policy to another is an important tool in Deep Reinforcement Learning. This process, referred to as distillation, has been used to great success, for example, by enhancing the optimisation of agents,…

Objective: Anemia is a frequent comorbidity in hemodialysis patients that can be successfully treated by administering erythropoiesis-stimulating agents (ESAs). ESAs dosing is currently based on clinical protocols that often do not account…

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Data in real-world application often exhibit skewed class distribution which poses an intense challenge for machine learning. Conventional classification algorithms are not effective in the case of imbalanced data distribution, and may fail…

Machine Learning · Computer Science 2019-01-08 Enlu Lin , Qiong Chen , Xiaoming Qi

We consider a problem of learning the reward and policy from expert examples under unknown dynamics. Our proposed method builds on the framework of generative adversarial networks and introduces the empowerment-regularized maximum-entropy…

Machine Learning · Computer Science 2019-02-26 Ahmed H. Qureshi , Byron Boots , Michael C. Yip

Reinforcement learning (RL) has garnered increasing recognition for its potential to optimise dynamic treatment regimes (DTRs) in personalised medicine, particularly for drug dosage prescriptions and medication recommendations. However, a…

Machine Learning · Computer Science 2024-05-30 Zhiyao Luo , Mingcheng Zhu , Fenglin Liu , Jiali Li , Yangchen Pan , Jiandong Zhou , Tingting Zhu

The development of quantum computational techniques has advanced greatly in recent years, parallel to the advancements in techniques for deep reinforcement learning. This work explores the potential for quantum computing to facilitate…

Quantum Physics · Physics 2020-08-31 Owen Lockwood , Mei Si

Reinforcement Learning (RL) is used extensively in Autonomous Systems (AS) as it enables learning at runtime without the need for a model of the environment or predefined actions. However, most applications of RL in AS, such as those based…

Artificial Intelligence · Computer Science 2024-10-01 Juan C. Rosero , Ivana Dusparic , Nicolás Cardozo

In modern power systems, frequency regulation is a fundamental prerequisite for ensuring system reliability and assessing the robustness of expansion projects. Conventional feedback control schemes, however, exhibit limited accuracy under…

Systems and Control · Electrical Eng. & Systems 2025-12-05 Amin Masoumi , Mert Korkali

The policy represented by the deep neural network can overfit the spurious features in observations, which hamper a reinforcement learning agent from learning effective policy. This issue becomes severe in high-dimensional state, where the…

Machine Learning · Computer Science 2023-05-01 Md Masudur Rahman , Yexiang Xue

The interpretability of deep learning is crucial for evaluating the reliability of medical imaging models and reducing the risks of inaccurate patient recommendations. This study addresses the "human out of the loop" and "trustworthiness"…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Haozhe Luo , Aurélie Pahud de Mortanges , Oana Inel , Abraham Bernstein , Mauricio Reyes