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We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

This paper describes an inverse analysis method using neural networks on optical spectroscopy, and its application to the quantitative optical constant evaluation. The present method consists of three subprocesses. First, measurable…

Optics · Physics 2023-08-28 Kyosuke Saeki , Takayuki Makino

We report an interpretation method for deep learning models that allows us to handle high-dimensional spectral data in materials science. The proposed method uses feature extraction and clustering analysis to categorize materials into…

Materials Science · Physics 2025-10-21 Akira Takahashi , Yu Kumagai , Arata Takamatsu , Fumiyasu Oba

Deep neural networks have been successfully applied in many different fields like computational imaging, medical healthcare, signal processing, or autonomous driving. In a proof-of-principle study, we demonstrate that computational optical…

Image and Video Processing · Electrical Eng. & Systems 2021-03-02 Lara Hoffmann , Clemens Elster

Deconvolution is the most commonly used image processing method to remove the blur caused by the point-spread-function (PSF) in optical imaging systems. While this method has been successful in deblurring, it suffers from several…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Huangxuan Zhao , Ziwen Ke , Ningbo Chen , Ke Li , Lidai Wang , Xiaojing Gong , Wei Zheng , Liang Song , Zhicheng Liu , Dong Liang , Chengbo Liu

The ability to perform nanometer-scale optical imaging and spectroscopy is key to deciphering the low-energy effects in quantum materials, as well as vibrational fingerprints in planetary and extraterrestrial particles, catalytic…

Scattering scanning near-field optical microscopy enables optical imaging and characterization of plasmonic devices with nanometer-scale resolution well below the diffraction limit. This technique enables developers to probe and understand…

Determining the dimensions of nanostructures is critical to ensuring the maximum performance of many geometry-sensitive nanoscale functional devices. However, accurate metrology at the nanoscale is difficult using optics-based methods due…

Applied Physics · Physics 2019-08-21 Jinlong Zhu , Yanan Liu , Sanyogita Purandare , Jian-Ming Jin , Shiyuan Liu , Lynford L. Goddard

Deblurring can not only provide visually more pleasant pictures and make photography more convenient, but also can improve the performance of objection detection as well as tracking. However, removing dynamic scene blur from images is a…

Computer Vision and Pattern Recognition · Computer Science 2023-01-19 Jiawei Zhang , Jinshan Pan , Daoye Wang , Shangchen Zhou , Xing Wei , Furong Zhao , Jianbo Liu , Jimmy Ren

We report on a novel methodology for extracting material parameters from spectroscopic optical data using a physics-based neural network. The proposed model integrates classical optimization frameworks with a multi-scale object detection…

Computational Physics · Physics 2025-03-12 M. Koumans , J. L. M. van Mechelen

Physics models typically contain adjustable parameters to reproduce measured data. While some parameters correspond directly to measured features in the data, others are unobservable. These unobservables can, in some cases, cause…

Nuclear Theory · Physics 2024-03-11 C. H. Kim , K. Y. Chae , M. S. Smith , D. W. Bardayan , C. R. Brune , R. J. deBoer , D. Lu , D. Odell

Deep-learning algorithms enable precise image recognition based on high-dimensional hierarchical image features. Here, we report the development and implementation of a deep-learning-based image segmentation algorithm in an autonomous…

Image and Video Processing · Electrical Eng. & Systems 2020-03-26 Satoru Masubuchi , Eisuke Watanabe , Yuta Seo , Shota Okazaki , Takao Sasagawa , Kenji Watanabe , Takashi Taniguchi , Tomoki Machida

Estimation of optical aberrations from volumetric intensity images is a key step in sensorless adaptive optics for 3D microscopy. Recent approaches based on deep learning promise accurate results at fast processing speeds. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Debayan Saha , Uwe Schmidt , Qinrong Zhang , Aurelien Barbotin , Qi Hu , Na Ji , Martin J. Booth , Martin Weigert , Eugene W. Myers

We propose to use deep learning to estimate parameters in statistical models when standard likelihood estimation methods are computationally infeasible. We show how to estimate parameters from max-stable processes, where inference is…

Methodology · Statistics 2021-08-02 Amanda Lenzi , Julie Bessac , Johann Rudi , Michael L. Stein

In this work we demonstrate the use of neural networks for rapid extraction of signal parameters of discretely sampled signals. In particular, we use dense autoencoder networks to extract the parameters of interest from exponentially…

Signal Processing · Electrical Eng. & Systems 2021-06-30 Jim C. Visschers , Dmitry Budker , Lykourgos Bougas

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Qishi Zhan , Dan Sun , Erdi Gao , Yuhan Ma , Yaxin Liang , Haowei Yang

Autonomous synthesis and characterization of inorganic materials requires the automatic and accurate analysis of X-ray diffraction spectra. For this task, we designed a probabilistic deep learning algorithm to identify complex multi-phase…

Materials Science · Physics 2021-05-27 Nathan J. Szymanski , Christopher J. Bartel , Yan Zeng , Qingsong Tu , Gerbrand Ceder

In recent years several methods to overcome diffraction limit in the far field microscopy have been demonstrated. Still the problem of superresolution is reliably solved only for fluorescent microscopy, giving a resolution of up to 20-30nm.…

Optics · Physics 2013-09-03 Yu. V. Miklyaev , S. A. Asselborn , K. A. Zaytsev , M. Ya. Darscht

Optical flow is a method aimed at predicting the movement velocity of any pixel in the image and is used in medicine and biology to estimate flow of particles in organs or organelles. However, a precise optical flow measurement requires…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Adrian Shajkofci , Michael Liebling
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