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The integration of artificial intelligence (AI) into medical imaging has advanced clinical diagnostics but poses challenges in managing model drift and ensuring long-term reliability. To address these challenges, we develop MMC+, an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Jameson Merkow , Felix J. Dorfner , Xiyu Yang , Alexander Ersoy , Giridhar Dasegowda , Mannudeep Kalra , Matthew P. Lungren , Christopher P. Bridge , Ivan Tarapov

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

Machine Learning (ML) models have gained popularity in medical imaging analysis given their expert level performance in many medical domains. To enhance the trustworthiness, acceptance, and regulatory compliance of medical imaging models…

Human-Computer Interaction · Computer Science 2025-06-06 Mischa Dombrowski , Andrea Prenner , Bernhard Kainz

Artificial intelligence (AI) is increasingly integrated into modern healthcare, offering powerful support for clinical decision-making. However, in real-world settings, AI systems may experience performance degradation over time, due to…

Artificial Intelligence · Computer Science 2026-02-05 Hao Guan , David Bates , Li Zhou

The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted…

Human-Computer Interaction · Computer Science 2020-01-22 Yao Xie , Melody Chen , David Kao , Ge Gao , Xiang 'Anthony' Chen

Medical diagnosis is not a single prediction from a fully specified vignette. It is a sequential workup: clinicians decide what evidence to obtain, revise a differential diagnosis, and stop when the diagnosis is sufficiently supported. Most…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jiazhen Pan , Weixiang Shen , Jun Li , Julian Canisius , Felix Bitzer , Paula Roßmüller , Jiancheng Yang , Virginie Kreutzinger , Daniel Rueckert , Benedikt Wiestler

Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

The continuous development of artificial intelligence (AI) theory has propelled this field to unprecedented heights, owing to the relentless efforts of scholars and researchers. In the medical realm, AI takes a pivotal role, leveraging…

Machine Learning · Computer Science 2024-12-04 Qiyang Sun , Alican Akman , Björn W. Schuller

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Since its renaissance, deep learning has been widely used in various medical imaging tasks and has achieved remarkable success in many medical imaging applications, thereby propelling us into the so-called artificial intelligence (AI) era.…

Computer Vision and Pattern Recognition · Computer Science 2021-03-08 S. Kevin Zhou , Hayit Greenspan , Christos Davatzikos , James S. Duncan , Bram van Ginneken , Anant Madabhushi , Jerry L. Prince , Daniel Rueckert , Ronald M. Summers

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Clinical data is often affected by clinically irrelevant factors such as discrepancies between measurement devices or differing processing methods between sites. In the field of machine learning (ML), these factors are known as domains and…

Purpose: The credibility of Artificial Intelligence (AI) models for medical imaging continues to be a challenge, affected by the diversity of models, the data used to train the models, and applicability of their combination to produce…

Image and Video Processing · Electrical Eng. & Systems 2026-02-18 Fakrul Islam Tushar , Lavsen Dahal , Saman Sotoudeh-Paima , Ehsan Abadi , W. Paul Segars , Ehsan Samei , Joseph Y. Lo

Artificial Intelligence (AI) has become commonplace to solve routine everyday tasks. Because of the exponential growth in medical imaging data volume and complexity, the workload on radiologists is steadily increasing. We project that the…

In AI-driven medical imaging, the failure to detect out-of-distribution (OOD) data poses a severe risk to clinical reliability, potentially leading to critical diagnostic errors. Current OOD detection methods often demand impractical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Dariush Lotfi , Mohammad-Ali Nikouei Mahani , Mohamad Koohi-Moghadam , Kyongtae Ty Bae

AI-based digital twins are at the leading edge of the Industry 4.0 revolution, which are technologically empowered by the Internet of Things and real-time data analysis. Information collected from industrial assets is produced in a…

Machine Learning · Computer Science 2023-03-20 Jesus L. Lobo , Ibai Laña , Eneko Osaba , Javier Del Ser

Machine learning (ML) applications in medical artificial intelligence (AI) systems have shifted from traditional and statistical methods to increasing application of deep learning models. This survey navigates the current landscape of…

Machine Learning · Computer Science 2024-01-23 Elisa Warner , Joonsang Lee , William Hsu , Tanveer Syeda-Mahmood , Charles Kahn , Olivier Gevaert , Arvind Rao

Camera images are ubiquitous in machine learning research. They also play a central role in the delivery of important services spanning medicine and environmental surveying. However, the application of machine learning models in these…

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo
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