Related papers: Spontaneous flow created by active topological def…
The complex spatiotemporal flow patterns in living tissues, driven by active forces, have many of the characteristics associated with inertial turbulence even though the Reynolds number is extremely low. Analyses of experimental data from…
We simulate the nonlocal Stokesian hydrodynamics of an elastic filament which is active due a permanent distribution of stresslets along its contour. A bending instability of an initially straight filament spontaneously breaks flow symmetry…
Flow networks can describe many natural and artificial systems. We present a model for a flow system that allows for volume accumulation, includes conduits with a non-linear relation between current and pressure difference, and can be…
Drops of active liquid crystal have recently shown the ability to self-propel, which was associated with topological defects in the orientation of active filaments [Sanchez {\em et al.}, Nature {\bf 491}, 431 (2013)]. Here, we study the…
We use a computational phase-field model together with analytical analysis to study how inter-cellular active forces can mediate individual cell morphology and collective motion in a confluent cell monolayer. Contractile inter-cellular…
We numerically investigate the morphology and disclination line dynamics of active nematic droplets in three dimensions. Although our model only incorporates the simplest possible form of achiral active stress, active nematic droplets…
Turbulent flows of incompressible liquid in two dimensions are comprised of dense systems of vortices. Such system of vortices can be treated as a fluid and itself could be described in terms of hydrodynamics. We develop the hydrodynamics…
Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…
We present a novel framework for the study of disclinations in two-dimensional active nematic liquid crystals, and topological defects in general. The order tensor formalism is used to calculate exact multi-particle solutions of the…
It is increasingly being realized that liquid-crystalline features can play an important role in the properties and dynamics of cell monolayers. Here, we present a cell-based model of cell layers, based on the phase-field formulation, that…
We study the dynamics of active nematic films on a substrate driven by active flows with or without the incompressible constraint.Through simulations and theoretical analysis, we show that arch patterns are stable in the compressible case,…
Topological defects are a ubiquitous phenomenon in diverse physical systems. In nematic liquid crystals (LCs), they are dynamic, physicochemically distinct, sensitive to stimuli, and are thereby promising for a range of applications.…
Liquid shells (e.g. double emulsions, vesicles etc.) are susceptible to interfacial instability and rupturing when driven out of mechanical equilibrium. This poses a significant challenge for the design of liquid shell based micro-machines,…
Coupling between flow and orientation is a central issue in understanding the collective dynamics of active biofilaments and cells. Active stresses generated by motor activity destroy (quasi-)long-range orientational order and induce…
Using agent-based simulations of self-propelled particles subject to short-range repulsion and nematic alignment we explore the dynamical phases of a dense active material confined to the surface of a sphere. We map the dynamical phase…
We investigate the effect of an anisotropic substrate on the turbulent dynamics of a simulated two dimensional active nematic. This is introduced as an anisotropic friction and an effective anisotropic viscosity, with the orientation of the…
Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces…
The balance between stretching and bending deformations characterizes shape transitions of thin elastic sheets. While stretching dominates the mechanical response in tension, bending dominates in compression after an abrupt buckling…
We describe a numerical investigation of a continuum model of an active nematic, concentrating on the regime of active turbulence. Results are presented for the effect of three parameters, activity, elastic constant and rotational diffusion…
The translation and shape deformations of a passive viscous Newtonian droplet immersed in an active nematic liquid crystal under circular confinement are analyzed using a linear stability analysis. We focus on the case of a sharply aligned…