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Cell alignment often forms nematic order, which can lead to anomalous collective cell flow due to the so-called active force. Although it is appreciated that cell migration is driven by traction force, a quantitative evaluation of the…

Soft Condensed Matter · Physics 2024-02-27 Masahito Uwamichi , He Li , Zihui Zhao , Yisong Yao , Hideo Higuchi , Kyogo Kawaguchi , Masaki Sano

We consider active nematodynamics on deformable surfaces. Based on a thermodynamically consistent surface Beris-Edwards model we add nematic activity and focus on the emerging additional coupling mechanism between the nematic field, the…

Soft Condensed Matter · Physics 2024-05-24 Ingo Nitschke , Axel Voigt

Although cell monolayers typically remain confluent, they can spontaneously develop persistent holes as a result of collective cellular motion. Recent studies on MDCK monolayers cultured on soft substrates have revealed that cells can align…

Soft Condensed Matter · Physics 2025-08-11 Diogo E. P. Pinto , Jan Rozman , Julia M. Yeomans

Many cell types spontaneously order like nematic liquid crystals, and, as such, they form topological defects. While defects with topological charge $\pm$1/2 are common in cell monolayers, the defects with charge $\pm$1, relevant in the…

Soft Condensed Matter · Physics 2019-12-09 Kirsten D. Endresen , MinSu Kim , Francesca Serra

We analyse the effect of anisotropy in elastic constants on the hydrodynamics of active nematics. Building on the multipole framework for a single elastic constant, we determine the leading effect of elastic anisotropy on the active…

Soft Condensed Matter · Physics 2025-11-12 Alexander J. H. Houston

Active polar fluids exhibit spontaneous flow when sufficient active stress is generated by internal molecular mechanisms. This is also referred to as an active Fr\'{e}edericksz transition. Experiments have revealed the existence of…

Soft Condensed Matter · Physics 2023-10-17 Abhinav Singh , Quentin Vagne , Frank Jülicher , Ivo F. Sbalzarini

In many active systems, swimmers collectively stir the surrounding fluid to stabilize some self-sustained vortices. The resulting nonequilibrium state is often referred to as active turbulence, by analogy with the turbulence of passive…

Statistical Mechanics · Physics 2026-03-03 Byjesh N. Radhakrishnan , Francesco Serafin , Thomas L. Schmidt , Étienne Fodor

Inspired by recent experiments that highlight the role of nematic defects in the morphogenesis of epithelial tissues, we develop a minimal framework to study the dynamics of an active curved surface driven by its nematic texture. Allowing…

Soft Condensed Matter · Physics 2022-09-14 Farzan Vafa , L. Mahadevan

The growing interest in active nematics and the emerging evidence of the relevance of topological defects in biology asks for reliable data analysis tools to identify, classify and track such defects in simulation and microscopy data. We…

Soft Condensed Matter · Physics 2020-02-10 Dennis Wenzel , Michael Nestler , Sebastian Reuther , Maximilian Simon , Axel Voigt

We study how confinement transforms the chaotic dynamics of bulk microtubule-based active nematics into regular spatiotemporal patterns. For weak confinements, multiple continuously nucleating and annihilating topological defects…

Active matter often simultaneously exhibits different kinds of orientational order and, in many cases of biological interest, undergoes continuous material renewal. In renewing nematopolar fluids we find stable topological strings,…

Soft Condensed Matter · Physics 2026-01-27 Alberto Dinelli , Ludovic Dumoulin , Karsten Kruse

Topological defects in nematically aligned cell populations play a critical role in modulating collective motion, from microbial colonies to epithelial tissues. Despite the potential of manipulating such topological defects to control…

Soft Condensed Matter · Physics 2023-07-25 Ryo Ienaga , Kazusa Beppu , Yusuke T. Maeda

Non-equilibrium dynamics of topological defects can be used as a fundamental propulsion mechanism in microscopic active matter. Here, we demonstrate swimming of topological defect-propelled colloidal particles in (passive) nematic fluids…

Soft Condensed Matter · Physics 2021-09-30 Tianyi Yao , Žiga Kos , Yimin Luo , Edward B. Steager , Miha Ravnik , Kathleen J. Stebe

The spontaneous emergence of collective flows is a generic property of active fluids and often leads to chaotic flow patterns characterised by swirls, jets, and topological disclinations in their orientation field. However, the ability to…

Soft Condensed Matter · Physics 2017-03-07 Tyler N. Shendruk , Amin Doostmohammadi , Kristian Thijssen , Julia M. Yeomans

Morphological trends in growing colonies of living cells are at the core of physiological and evolutionary processes. Using active gel equations, which include cell division, we show that shape changes during the growth can be regulated by…

Soft Condensed Matter · Physics 2016-07-27 Amin Doostmohammadi , Sumesh P. Thampi , Julia M. Yeomans

Using novel micro-printing techniques, we develop a versatile experimental setup that allows us to study how lateral confinement tames the active flows and defect properties of the microtubule/kinesin active nematic system. We demonstrate…

Living materials at different length scales manifest active nematic features such as orientational order, nematic topological defects, and active nematic turbulence. Using numerical simulations we investigate the impact of fluid inertia on…

Soft Condensed Matter · Physics 2022-08-10 Roozbeh Saghatchi , Mehmet Yildiz , Amin Doostmohammadi

We investigate similarities in the micro-structural dynamics between externally driven and actively driven nematics. Walls, lines of strong deformations in the director field, and topological defects are characteristic features of an active…

Soft Condensed Matter · Physics 2015-04-28 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

Soft Condensed Matter · Physics 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza

Using a minimal hydrodynamic model, we theoretically and computationally study active gels in straight and annular two-dimensional channels subject to an externally imposed shear. The gels are isotropic in the absence of externally- or…

Soft Condensed Matter · Physics 2023-07-25 Wan Luo , Aparna Baskaran , Robert A. Pelcovits , Thomas R. Powers
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