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Membranous nephropathy (MN) is a frequent type of adult nephrotic syndrome, which has a high clinical incidence and can cause various complications. In the biopsy microscope slide of membranous nephropathy, spikelike projections on the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Yilin Chen , Ming Li , Yongfei Wu , Xueyu Liu , Fang Hao , Daoxiang Zhou , Xiaoshuang Zhou , Chen Wang

Accurate segmentation of glomerulus instances attains high clinical significance in the automated analysis of renal biopsies to aid in diagnosing and monitoring kidney disease. Analyzing real-world histopathology images often encompasses…

We present a fully automated, two-stage modular glottal area segmentation framework for high-speed videoendoscopy (HSV) designed for accuracy, generalizability, and real-time playback. Our detection-gated pipeline combines a YOLOv8n glottis…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Harikrishnan Unnikrishnan , Rita Patel

The Gaussian process (GP) regression can be severely biased when the data are contaminated by outliers. This paper presents a new robust GP regression algorithm that iteratively trims the most extreme data points. While the new algorithm…

Machine Learning · Computer Science 2021-06-15 Zhao-Zhou Li , Lu Li , Zhengyi Shao

Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Automated grading of prostate cancer histopathology images is a challenging task, with one key challenge being the scarcity of annotations down to the level of regions of interest (strong labels), as typically the prostate cancer Gleason…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Eirini Arvaniti , Manfred Claassen

Finite Gaussian mixture models provide a powerful and widely employed probabilistic approach for clustering multivariate continuous data. However, the practical usefulness of these models is jeopardized in high-dimensional spaces, where…

Methodology · Statistics 2022-05-13 Alessandro Casa , Andrea Cappozzo , Michael Fop

Spectral clustering is a powerful technique for clustering high-dimensional data, utilizing graph-based representations to detect complex, non-linear structures and non-convex clusters. The construction of a similarity graph is essential…

Machine Learning · Computer Science 2025-01-27 Kamal Berahmand , Farid Saberi-Movahed , Razieh Sheikhpour , Yuefeng Li , Mahdi Jalili

It is important to identify the discriminative features for high dimensional clustering. However, due to the lack of cluster labels, the regularization methods developed for supervised feature selection can not be directly applied. To learn…

Machine Learning · Statistics 2025-07-16 Zhaoyu Xing , Yang Wan , Juan Wen , Wei Zhong

Meibography is a non-contact imaging technique used by ophthalmologists to assist in the evaluation and diagnosis of meibomian gland dysfunction (MGD). While artificial qualitative analysis of meibography images could lead to low…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Peng Xiao , Zhongzhou Luo , Yuqing Deng , Gengyuan Wang , Jin Yuan

Domain Generalized Semantic Segmentation (DGSS) aims to improve the generalization ability of models across unseen domains without access to target data during training. Recent advances in DGSS have increasingly exploited vision foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Xinhui Li , Xiaojie Guo

We consider the consistency properties of a regularised estimator for the simultaneous identification of both changepoints and graphical dependency structure in multivariate time-series. Traditionally, estimation of Gaussian Graphical…

Statistics Theory · Mathematics 2017-12-18 Alex J. Gibberd , Sandipan Roy

Healthcare data, particularly in critical care settings, presents three key challenges for analysis. First, physiological measurements come from different sources but are inherently related. Yet, traditional methods often treat each…

Applications · Statistics 2025-12-01 Ali Akbar Septiandri , Deyu Ming , F. Alejandro DiazDelaO , Takoua Jendoubi , Samiran Ray

Constructing a multi-modal automatic classification model based on three types of renal biopsy images can assist pathologists in glomerular multi-disease identification. However, the substantial scale difference between transmission…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Kaixing Long , Danyi Weng , Yun Mi , Zhentai Zhang , Yanmeng Lu , Jian Geng , Zhitao Zhou , Liming Zhong , Qianjin Feng , Wei Yang , Lei Cao

Personalized diagnoses have not been possible due to sear amount of data pathologists have to bear during the day-to-day routine. This lead to the current generalized standards that are being continuously updated as new findings are…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Zeyu Gao , Haichuan Zhang , Ruonan Zhang , Tieliang Gong , Chunbao Wang , Chen Li

Knowledge Graph (KG) plays a crucial role in Medical Report Generation (MRG) because it reveals the relations among diseases and thus can be utilized to guide the generation process. However, constructing a comprehensive KG is…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Yixin Wang , Zihao Lin , Haoyu Dong

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Graph Neural Networks (GNNs) have shown remarkable performance in the healthcare domain. However, what remained challenging is quantifying the predictive uncertainty of GNNs, which is an important aspect of trustworthiness in clinical…

Machine Learning · Computer Science 2025-08-28 Hirad Daneshvar , Reza Samavi

Line segment detection is an essential task in computer vision and image analysis, as it is the critical foundation for advanced tasks such as shape modeling and road lane line detection for autonomous driving. We present a robust…

Computer Vision and Pattern Recognition · Computer Science 2020-03-02 Ming Gong , Liping Yang , Catherine Potts , Vijayan K. Asari , Diane Oyen , Brendt Wohlberg