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Multiscale molecular modeling is widely applied in scientific research of molecular properties over large time and length scales. Two specific challenges are commonly present in multiscale modeling, provided that information between the…
Segmenting glomerular intraglomerular tissue and lesions traditionally depends on detailed morphological evaluations by expert nephropathologists, a labor-intensive process susceptible to interobserver variability. Our group previously…
Whole-slide image analysis is essential for diagnostic tasks in pathology, yet existing deep learning methods primarily rely on flat classification, ignoring hierarchical relationships among class labels. In this study, we propose HiClass,…
Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…
Glioma, a prevalent and heterogeneous tumor originating from the glial cells, can be differentiated as Low Grade Glioma (LGG) and High Grade Glioma (HGG) according to World Health Organization's norms. Classifying gliomas is essential for…
Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…
The real-world data distribution is essentially long-tailed, which poses great challenge to the deep model. In this work, we propose a new method, Gradual Balanced Loss and Adaptive Feature Generator (GLAG) to alleviate imbalance. GLAG…
An approach to utilize recent advances in deep generative models for anomaly detection in a granular (continuous) sense on a real-world image dataset with quality issues is detailed using recent normalizing flow models, with implications in…
Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…
Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to…
Graph neural networks (GNNs) have shown promise in addressing graph-related problems, including node classification. However, conventional GNNs assume an even distribution of data across classes, which is often not the case in real-world…
Graph Neural Networks (GNNs) have achieved unprecedented success in identifying categorical labels of graphs. However, most existing graph classification problems with GNNs follow the protocol of balanced data splitting, which misaligns…
Embedding learning (EL) and feature synthesizing (FS) are two of the popular categories of fine-grained GZSL methods. EL or FS using global features cannot discriminate fine details in the absence of local features. On the other hand, EL or…
Gradient sampling (GS) has proved to be an effective methodology for the minimization of objective functions that may be nonconvex and/or nonsmooth. The most computationally expensive component of a contemporary GS method is the need to…
Gastrointestinal (GI) tract image analysis plays a crucial role in medical diagnosis. This research addresses the challenge of accurately classifying and segmenting GI images for real-time applications, where traditional methods often…
Multi-view subspace clustering (MSC) is a popular unsupervised method by integrating heterogeneous information to reveal the intrinsic clustering structure hidden across views. Usually, MSC methods use graphs (or affinity matrices) fusion…
Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…
Histopathological assessments, including surgical resection and core needle biopsy, are the standard procedures in the diagnosis of the prostate cancer. Current interpretation of the histopathology images includes the determination of the…
Recently, 3D Gaussian Splatting has emerged as a prominent research direction owing to its ultrarapid training speed and high-fidelity rendering capabilities. However, the unstructured and irregular nature of Gaussian point clouds poses…
Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…