Related papers: Towards machine learning aided real-time range ima…
Background: Intensity-modulated proton therapy (IMPT) using pencil beam technique scans tumor in a layer by layer, then spot by spot manner. It can provide highly conformal dose to tumor targets and spare nearby organs-at-risk (OAR). Fast…
Protoacoustic imaging showed great promise in providing real-time 3D dose verification of proton therapy. However, the limited acquisition angle in protoacoustic imaging induces severe artifacts, which significantly impairs its accuracy for…
We investigate the performance of large area radiation detectors, with high energy- and spatial-resolution, intended for the development of a Total Energy Detector with gamma-ray imaging capability, so-called i-TED. This new development…
Although the MeV gamma-ray band is a promising energy-band window in astrophysics, the current situation of MeV gamma-ray astronomy significantly lags behind those of the other energy bands in angular resolution and sensitivity. An…
The Mega electron volt (MeV) gamma-ray observation is a promising diagnostic tool for observing the universe. However, the sensitivity of MeV gamma-ray telescopes is limited due to peculiar backgrounds, restricting the application of MeV…
Organ-at-risk contouring is still a bottleneck in radiotherapy, with many deep learning methods falling short of promised results when evaluated on clinical data. We investigate the accuracy and time-savings resulting from the use of an…
A prototype of the MeV gamma-ray imaging camera based on the full reconstruction of the Compton process has been developed. This camera consists of a micro-TPC that is a gaseous Time Projection Chamber (TPC) and scintillation cameras. With…
Hadrontherapy is a novel technique of cancer radiation therapy which employs beams of charged hadrons, protons and carbon ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal…
Study of high energy cosmic events in the MeV range requires detector with high efficiency and energy resolution to be constructed. The present setup consisting of scintillator crystals CeBr3 with different thickness, each coupled with 12 x…
We develop a compact transmon emitter/detector (TED) superconducting circuit and demonstrate its dual functionality as a single-photon source and detector. In our setup, photons emitted by a source TED are transmitted via a meter-long…
High-quality proton beams generated by laser-plasma interactions are of significant interest for applications ranging from tumor therapy to fast ignition in inertial confinement fusion. However, simultaneously achieving high energy coupling…
In order to fully exploit the ballistic potential of particle therapy, we propose an online range monitoring concept based on high-resolution Time-Of-Flight (TOF)-resolved Prompt Gamma (PG) detection in a single proton counting regime. In a…
In this study, we introduce a Compton SPECT system for whole-body imaging of Actinium-225 (225Ac), one of the trending radionuclides for targeted alpha therapy (TAT). The Compton SPECT system enables multi-energy gamma photon detection with…
Proton radiography is used in various high-energy-density (HED) plasma experiments. In this paper, we describe a Monte Carlo and ray-tracing simulation tool called MPRAD that can be used for modeling the deflection of proton beams in…
The detection of photons with energies greater than a few tenths of an MeV, interacting via Compton scattering and/or pair production, faces a number of difficulties. The reconstruction of single-scatter Compton events can only determine…
The Soft Gamma-ray Detector (SGD) is one of the instrument payloads onboard ASTRO-H, and will cover a wide energy band (60--600 keV) at a background level 10 times better than instruments currently in orbit. The SGD achieves low background…
This study aims to assess the composition of scattered particles generated in proton therapy for tumours situated proximal to titanium dental implants. The investigation involves decomposing the mixed field and recording Linear Energy…
Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments is still a matter of research. A possible technique exploits the information…
We developed a novel gamma-ray detection system (TIARA) for range monitoring in Particle Therapy. The system employs Cherenkov-based gamma-ray detection modules arranged around the target or patient, operated in time coincidence with a fast…
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…