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Blocking is often used to reduce known variability in designed experiments by collecting together homogeneous experimental units. A common modelling assumption for such experiments is that responses from units within a block are dependent.…

Methodology · Statistics 2018-11-07 W. G. Mueller , A. Rappold , D. C. Woods

Dose-finding trials are a key component of the drug development process and rely on a statistical design to help inform dosing decisions. Triallists wishing to choose a design require knowledge of operating characteristics of competing…

Computation · Statistics 2025-03-11 Michael Sweeting , Daniel Slade , Dan Jackson , Kristian Brock

Matching mechanisms play a central role in operations management across diverse fields including education, healthcare, and online platforms. However, experimentally comparing a new matching algorithm against a status quo presents some…

Methodology · Statistics 2026-01-30 Chonghuan Wang

Online controlled experiments are the primary tool for measuring the causal impact of product changes in digital businesses. It is increasingly common for digital products and services to interact with customers in a personalised way. Using…

Methodology · Statistics 2021-07-02 C. H. Bryan Liu , Benjamin Paul Chamberlain

During the last few decades, online controlled experiments (also known as A/B tests) have been adopted as a golden standard for measuring business improvements in industry. In our company, there are more than a billion users participating…

Applications · Statistics 2021-08-06 Tao Xiong , Yihan Bao , Penglei Zhao , Yong Wang

Designs for Order-of-Addition (OofA) experiments have received growing attention due to their impact on responses based on the sequence of component addition. In certain cases, these experiments involve heterogeneous groups of units, which…

Methodology · Statistics 2026-02-04 Chang-Yun Lin

Matched-pair experimental designs aim to detect treatment effects by pairing participants and comparing within-pair outcome differences. In many situations, the overall effect size across the entire population is small. Then, the focus…

Machine Learning · Computer Science 2025-09-26 Weizhi Li , Gautam Dasarathy , Visar Berisha

Both cluster randomized trials and quasi-experimental designs are used to evaluate the impact of health and social policies and interventions. Stepped-wedge cluster randomized trials randomize a staggered adoption approach, while recent…

Methodology · Statistics 2026-04-15 Haidong Lu , Gregg S. Gonsalves , Fan Li , Guanyu Tong , Lee Kennedy-Shaffer

With the growing needs of online A/B testing to support the innovation in industry, the opportunity cost of running an experiment becomes non-negligible. Therefore, there is an increasing demand for an efficient continuous monitoring…

Machine Learning · Computer Science 2023-04-04 Runzhe Wan , Yu Liu , James McQueen , Doug Hains , Rui Song

We study the discrete bin covering problem where a multiset of items from a fixed set $S \subseteq (0,1]$ must be split into disjoint subsets while maximizing the number of subsets whose contents sum to at least $1$. We study the online…

Data Structures and Algorithms · Computer Science 2024-01-29 Magnus Berg , Shahin Kamali

Despite the benefits of personalizing items and information tailored to users' needs, it has been found that recommender systems tend to introduce biases that favor popular items or certain categories of items, and dominant user groups. In…

Information Retrieval · Computer Science 2024-01-01 Yongsu Ahn , Yu-Ru Lin

Adaptive approaches, allowing for more flexible trial design, have been proposed for individually randomized trials to save time or reduce sample size. However, adaptive designs for cluster-randomized trials in which groups of participants…

Methodology · Statistics 2022-01-10 Junwei Shen , Shirin Golchi , Erica E. M. Moodie , David Benrimoh

Optimizing recommender systems based on user interaction data is mainly seen as a problem of dealing with selection bias, where most existing work assumes that interactions from different users are independent. However, it has been shown…

Information Retrieval · Computer Science 2022-07-04 Norman Knyazev , Harrie Oosterhuis

Classical approaches to experimental design assume that intervening on one unit does not affect other units. There are many important settings, however, where this non-interference assumption does not hold, as when running experiments on…

Optimization and Control · Mathematics 2020-07-01 Stefan Wager , Kuang Xu

Randomized experimentation (also known as A/B testing or bucket testing) is widely used in the internet industry to measure the metric impact obtained by different treatment variants. A/B tests identify the treatment variant showing the…

Significant advances in edge computing capabilities enable learning to occur at geographically diverse locations. In general, the training data needed in those learning tasks are not only heterogeneous but also not fully generated locally.…

Networking and Internet Architecture · Computer Science 2022-01-14 Yuezhou Liu , Yuanyuan Li , Lili Su , Edmund Yeh , Stratis Ioannidis

A fundamental issue in causal inference for Big Observational Data is confounding due to covariate imbalances between treatment groups. This can be addressed by designing the data prior to analysis. Existing design methods, developed for…

Methodology · Statistics 2022-03-17 Yumin Zhang , Arman Sabbaghi

We consider the problem of how to assign treatment in a randomized experiment, in which the correlation among the outcomes is informed by a network available pre-intervention. Working within the potential outcome causal framework, we…

Methodology · Statistics 2017-05-19 Guillaume W. Basse , Edoardo M. Airoldi

The optimal design of experiments typically involves solving an NP-hard combinatorial optimization problem. In this paper, we aim to develop a globally convergent and practically efficient optimization algorithm. Specifically, we consider a…

Econometrics · Economics 2022-11-29 Yiping Lu , Jiajin Li , Lexing Ying , Jose Blanchet

Experiments deliver credible treatment-effect estimates but, because they are costly, are often restricted to specific sites, small populations, or particular mechanisms. A common practice across several fields is therefore to combine…

Econometrics · Economics 2025-12-30 Aristotelis Epanomeritakis , Davide Viviano