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Tissue manipulation is a frequently used fundamental subtask of any surgical procedures, and in some cases it may require the involvement of a surgeon's assistant. The complex dynamics of soft tissue as an unstructured environment is one of…

A computer aided maxillofacial sequence is presented, applied to orthognatic surgery. It consists of 5 main stages: data acquisition and integration, surgical planning, surgical simulation, and per operative assistance. The planning and…

Medical Physics · Physics 2007-05-23 Matthieu Chabanas , Christophe Marecaux , Yohan Payan , Franck Boutault

We investigate numerically a quasi-static elasticity system of Kachanov-type. To do so we propose an Euler time discretization combined with a suitable finite elements scheme (FEM) to handle the discretization is space. We use ODE-type…

Numerical Analysis · Mathematics 2022-02-15 Simon Grützner , Adrian Muntean

We present an algorithm that allows a user within a virtual environment to perform real-time unconstrained cuts or consecutive tears, i.e., progressive, continuous fractures on a deformable rigged and soft-body mesh model in…

Lower limb amputees often suffer skin and tissue problems from using their prosthesis which is a challenging biomechanical problem. The finite element method (FEM) has previously been applied to analyse internal mechanical conditions of the…

Medical Physics · Physics 2019-08-02 Sara Kallin , Asim Rashid , Kent Salomonsson , Peter Hansbo

The study of pathological cardiac conditions such as arrhythmias, a major cause of mortality in heart failure, is becoming increasingly informed by computational simulation, numerically modelling the governing equations. This can provide…

Computational Engineering, Finance, and Science · Computer Science 2014-06-09 Nathan Kirk , Alan Benson , Christopher Goodyer , Matthew Hubbard

In this thesis, a computational framework for microstructural modelling of transverse behaviour of heterogeneous materials is presented. The context of this research is part of the broad and active field of Computational Micromechanics,…

Computational Engineering, Finance, and Science · Computer Science 2021-10-05 Marco Lo Cascio

Purpose: Radio-frequency ablations play an important role in the therapy of malignant liver lesions. The navigation of a needle to the lesion poses a challenge for both the trainees and intervening physicians. Methods: This publication…

Medical Physics · Physics 2019-07-18 Niclas Kath , Heinz Handels , Andre Mastmeyer

Diabetic foot ulcers are triggered by mechanical loadings applied to the surface of the plantar skin. Strain is considered to play a crucial role in relation to ulcer etiology and can be assessed by Finite Element (FE) modelling. A…

Medical Physics · Physics 2023-07-19 Alessio Trebbi , Nolwenn Fougeron , Yohan Payan

Mammography is a specific type of breast imaging that uses low-dose X-rays to detect cancer in early stage. During the exam, the women breast is compressed between two plates until a nearly uniform breast thickness is obtained. This…

Medical Physics · Physics 2018-11-26 Mîra Anna , Ann-Katherine Carton , Serge Muller , Yohan Payan

The use of machine learning algorithms to predict behaviors of complex systems is booming. However, the key to an effective use of machine learning tools in multi-physics problems, including combustion, is to couple them to physical and…

This scientific paper explores two distinct approaches for identifying and approximating the simulation model, particularly in the context of the snap process crucial to medical device assembly. Simulation models play a pivotal role in…

Machine Learning · Computer Science 2023-09-27 Fatemeh Kakavandi

Finite element analysis (FEA) can be used to evaluate applied interface pressures and internal tissue strains for computational prosthetic socket design. This type of framework requires realistic patient-specific limb geometry and…

Medical Physics · Physics 2022-11-24 Bryan J. Ranger , Kevin M. Moerman , Brian W. Anthony , Hugh M. Herr

In the continual effort to improve product quality and decrease operations costs, computational modeling is increasingly being deployed to determine feasibility of product designs or configurations. Surrogate modeling of these computer…

Machine Learning · Statistics 2021-11-10 Nathan Wycoff , Mickaël Binois , Robert B. Gramacy

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

We present a multiagent-based model that captures the interactions between different types of cells with their microenvironment, and enables the analysis of the emergent global behavior during tissue regeneration and tumor development.…

Biological Physics · Physics 2023-01-31 Luciana Melina Luque , Carlos Manuel Carlevaro , Camilo Llamoza Torres , Enrique Lomba

A continuum description is essential for understanding a variety of collective phenomena in active matter. However, building quantitative continuum models of active matter from first principles can be extremely challenging due to both the…

Soft Condensed Matter · Physics 2022-10-19 Matthew Golden , Roman Grigoriev , Jyothishraj Nambisan , Alberto Fernandez-Nieves

Classically, the constitutive behavior of materials is described either phenomenologically, or by homogenization approaches. Phenomenological approaches are computationally very efficient, but are limited for complex non-linear and…

Computational Physics · Physics 2020-01-28 Christoph Settgast , Geralf Hütter , Meinhard Kuna , Martin Abendroth

An adventure at engineering design and modeling is possible with a Virtual Reality Environment (VRE) that uses multiple computer-generated media to let a user experience situations that are temporally and spatially prohibiting. In this…

Computational Engineering, Finance, and Science · Computer Science 2007-08-15 L. -V. Bochkareva , M. -V. Kireitseu , G. R. Tomlinson , H. Altenbach , V. Kompis , D. Hui

Application of machine learning techniques enables segmentation of functional tissue units in histology whole-slide images (WSIs). We built a pipeline to apply previously validated segmentation models of kidney structures and extract…