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Real-time simulation of elastic structures is essential in many applications, from computer-guided surgical interventions to interactive design in mechanical engineering. The Finite Element Method is often used as the numerical method of…

Machine Learning · Computer Science 2021-09-21 Alban Odot , Ryadh Haferssas , Stéphane Cotin

We evaluate a number of different finite element approaches for fluid-structure (contact) interaction problems against data from physical experiments. For this we take the data from experiments by Hagemeier [Mendeley Data, doi:…

Fluid Dynamics · Physics 2021-03-03 Henry von Wahl , Thomas Richter , Stefan Frei , Thomas Hagemeier

Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions remain poorly understood. This study aimed to establish an…

Simulation of fracturing processes in porous rocks can be divided into two main branches: (i) modeling the rock as a continuum which is enhanced with special features to account for fractures, or (ii) modeling the rock by a discrete (or…

Numerical Analysis · Mathematics 2017-02-07 Halvor Møll Nilsen , Idar Larsen , Xavier Raynaud

Developing computational models of the human jaw acquired from cone-beam computed tomography (CBCT) scans is time-consuming and labor-intensive. Besides, a quantitative comparison is not attainable in the literature due to the involved…

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

We introduce a numerical workflow to model and simulate transient close-contact melting processes based on the space-time finite element method. That is, we aim at computing the velocity at which a forced heat source melts through a…

Numerical Analysis · Mathematics 2023-06-01 Leonardo Boledi , Fabian Key , Benjamin Terschanski , Stefanie Elgeti , Julia Kowalski

In medicolegal situations, the consequences of a stabbing incident are described in terms that are qualitative without being quantitative. Here, the mechanical variables involved in knife-tissue penetration events are used to determine the…

Classical Physics · Physics 2008-11-25 Michael D. Gilchrist , Stephen Keenan , Michael Curtis , Mary Cassidy , Greg Byrne , Michel Destrade

Neurosurgery interventions involve complex tracking systems because a tissue deformation takesplace. The neuronavigation system relies only on preoperative images. In order to overcome the soft tissue deformations and guarantee the accuracy…

Medical Physics · Physics 2007-10-03 Claudio Lobos , Marek Bucki , Yohan Payan , Nancy Hitschfeld

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

This paper presents a survey of the state-of-the-art deformable models studied in the literature concerning soft tissue deformable modeling for interactive surgical simulation. It first introduces the challenges of surgical simulation,…

Computational Engineering, Finance, and Science · Computer Science 2019-09-10 Jinao Zhang , Yongmin Zhong , Chengfan Gu

Studying the peeling behaviour of adhesives on skin is vital for advancing biomedical applications such as medical adhesives and transdermal patches. Traditional methods like experimental testing and finite element method (FEM), though…

Medical Physics · Physics 2025-06-26 Ashish Masarkar , Rakesh Gupta , Naga Neehar Dingari , Beena Rai

Herein, we present a new data-driven multiscale framework called FE${}^\text{ANN}$ which is based on two main keystones: the usage of physics-constrained artificial neural networks (ANNs) as macroscopic surrogate models and an autonomous…

Computational Engineering, Finance, and Science · Computer Science 2023-09-06 Karl A. Kalina , Lennart Linden , Jörg Brummund , Markus Kästner

Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A…

The purpose of this study was to develop a method for tissue elasticity imaging using tagged magnetic resonance imaging (MRI). First, we developed a cyclic pressure device that used air to remotely transmit the power to generate cyclic…

Medical Physics · Physics 2020-02-07 Tomoki Takeuchi , Ryosuke Nasada , Kenya Murase

Pressure ulcers are a severe disease affecting patients that are bedridden or in a wheelchair bound for long periods of time. These wounds can develop in the deep layers of the skin of specific parts of the body, mostly on heels or sacrum,…

In medicine, needles are frequently used to deliver treatments to subsurface targets or to take tissue samples from the inside of an organ. Current clinical practice is to insert needles under image guidance or haptic feedback, although…

Systems and Control · Electrical Eng. & Systems 2020-04-29 Antje Rogalla , Sascha Lehmann , Maximilian Neidhardt , Johanna Sprenger , Marcel Bengs , Alexander Schlaefer , Sibylle Schupp

Tissue biopsy is the gold standard for diagnosing many diseases, involving the extraction of diseased tissue for histopathology analysis by expert pathologists. However, this procedure has two main limitations: 1) Manual sampling through…

Robotics · Computer Science 2025-09-03 Fanxin Wang , Yikun Cheng , Chuyuan Tao , Rohit Bhargava , Thenkurussi Kesavadas

The present level of development of molecular force field methods is assessed from the point of view of simulation-based engineering, outlining the immediate perspective for further development and highlighting the newly emerging discipline…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-22 Martin Horsch , Christoph Niethammer , Jadran Vrabec , Hans Hasse

Purpose. Precise placement of needles is a challenge in a number of clinical applications such as brachytherapy or biopsy. Forces acting at the needle cause tissue deformation and needle deflection which in turn may lead to misplacement or…