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Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

Computational Pathology (CPath) is an emerging field concerned with the study of tissue pathology via computational algorithms for the processing and analysis of digitized high-resolution images of tissue slides. Recent deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Amina Asif , Kashif Rajpoot , David Snead , Fayyaz Minhas , Nasir Rajpoot

Deep learning models are routinely employed in computational pathology (CPath) for solving problems of diagnostic and prognostic significance. Typically, the generalization performance of CPath models is analyzed using evaluation protocols…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Alex Foote , Amina Asif , Ayesha Azam , Tim Marshall-Cox , Nasir Rajpoot , Fayyaz Minhas

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Deep learning models have shown immense promise in computational pathology (CPath) tasks, but their performance often suffers when applied to unseen data due to domain shifts. Addressing this requires domain generalization (DG) algorithms.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Neda Zamanitajeddin , Mostafa Jahanifar , Kesi Xu , Fouzia Siraj , Nasir Rajpoot

While machine learning offers diverse techniques suitable for exploring various medical research questions, a cohesive synergistic framework can facilitate the integration and understanding of new approaches within unified model development…

Machine Learning · Computer Science 2025-01-09 Ramtin Zargari Marandi , Anne Svane Frahm , Jens Lundgren , Daniel Dawson Murray , Maja Milojevic

Deep learning models for medical image segmentation and object detection are becoming increasingly available as clinical products. However, as details are rarely provided about the training data, models may unexpectedly fail when cases…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Jack Highton , Quok Zong Chong , Samuel Finestone , Arian Beqiri , Julia A. Schnabel , Kanwal K. Bhatia

Computational pathology (CPath) digitizes pathology slides into whole slide images (WSIs), enabling analysis for critical healthcare tasks such as cancer diagnosis and prognosis. However, WSIs possess extremely long sequence lengths (up to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Wenhao Tang , Heng Fang , Ge Wu , Xiang Li , Ming-Ming Cheng

Foundation models for computational pathology have shown great promise for specimen-level tasks and are increasingly accessible to researchers. However, specimen-level models built on these foundation models remain largely unavailable,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Jakub R. Kaczmarzyk , Rishul Sharma , Peter K. Koo , Joel H. Saltz

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Histologic examination plays a crucial role in oncology research and diagnostics. The adoption of digital scanning of whole slide images (WSI) has created an opportunity to leverage deep learning-based image classification methods to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Md Zahangir Alom , Quynh T. Tran , Brent A. Orr

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Deep neural networks have shown impressive performance for image-based disease detection. Performance is commonly evaluated through clinical validation on independent test sets to demonstrate clinically acceptable accuracy. Reporting good…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Mobarakol Islam , Zeju Li , Ben Glocker

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

Training deep neural network classifiers that are certifiably robust against adversarial attacks is critical to ensuring the security and reliability of AI-controlled systems. Although numerous state-of-the-art certified training methods…

Machine Learning · Computer Science 2022-10-27 Pratik Vaishnavi , Kevin Eykholt , Amir Rahmati

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Along with the successful deployment of deep neural networks in several application domains, the need to unravel the black-box nature of these networks has seen a significant increase recently. Several methods have been introduced to…

Machine Learning · Computer Science 2023-07-06 Adam Ivankay , Mattia Rigotti , Pascal Frossard

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Network robustness plays a crucial role in our understanding of complex interconnected systems such as transportation, communication, and computer networks. While significant research has been conducted in the area of network robustness, no…

Social and Information Networks · Computer Science 2021-08-17 Scott Freitas , Diyi Yang , Srijan Kumar , Hanghang Tong , Duen Horng Chau
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