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This paper aims to evaluate the suitability of current deep learning methods for clinical workflow especially by focusing on dermatology. Although deep learning methods have been attempted to get dermatologist level accuracy in several…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Sourav Mishra , Subhajit Chaudhury , Hideaki Imaizumi , Toshihiko Yamasaki

Sensitivity to staining variation remains a major barrier to deploying computational pathology (CPath) models as hematoxylin and eosin (H&E) staining varies across laboratories, requiring systematic assessment of how this variability…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Lydia A. Schönpflug , Nikki van den Berg , Sonali Andani , Nanda Horeweg , Jurriaan Barkey Wolf , Tjalling Bosse , Viktor H. Koelzer , Maxime W. Lafarge

The rise of deep learning has marked significant progress in fields such as computer vision, natural language processing, and medical imaging, primarily through the adaptation of pre-trained models for specific tasks. Traditional…

Machine Learning · Computer Science 2024-04-25 Charith Chandra Sai Balne , Sreyoshi Bhaduri , Tamoghna Roy , Vinija Jain , Aman Chadha

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Parameter-efficient tuning (PET) techniques calibrate the model's predictions on downstream tasks by freezing the pre-trained models and introducing a small number of learnable parameters. However, despite the numerous PET methods proposed,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Jiacheng Ruan , Xian Gao , Suncheng Xiang , Mingye Xie , Ting Liu , Yuzhuo Fu

Adversarial patches are optimized contiguous pixel blocks in an input image that cause a machine-learning model to misclassify it. However, their optimization is computationally demanding, and requires careful hyperparameter tuning,…

Cryptography and Security · Computer Science 2025-01-16 Maura Pintor , Daniele Angioni , Angelo Sotgiu , Luca Demetrio , Ambra Demontis , Battista Biggio , Fabio Roli

The robustness of deep neural networks is usually lacking under adversarial examples, common corruptions, and distribution shifts, which becomes an important research problem in the development of deep learning. Although new deep learning…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Chang Liu , Yinpeng Dong , Wenzhao Xiang , Xiao Yang , Hang Su , Jun Zhu , Yuefeng Chen , Yuan He , Hui Xue , Shibao Zheng

Current interest in deep learning captures the attention of many programmers and researchers. Unfortunately, the lack of a unified schema for developing deep learning models results in methodological inconsistencies, unclear documentation,…

Machine Learning · Computer Science 2025-02-27 Sebastian Chwilczyński , Kacper Trębacz , Karol Cyganik , Mateusz Małecki , Dariusz Brzezinski

The application of new artificial intelligence (AI) discoveries is transforming healthcare research. However, the standards of reporting are variable in this still evolving field, leading to potential research waste. The aim of this work is…

Computers and Society · Computer Science 2023-01-25 Clare McGenity , Darren Treanor

Recent studies have shown that higher accuracy on ImageNet usually leads to better robustness against different corruptions. Therefore, in this paper, instead of following the traditional research paradigm that investigates new…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Xiaodan Li , Yuefeng Chen , Yao Zhu , Shuhui Wang , Rong Zhang , Hui Xue

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Deep learning techniques hold immense promise for advancing medical image analysis, particularly in tasks like image segmentation, where precise annotation of regions or volumes of interest within medical images is crucial but manually…

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Retrieval-Augmented Generation (RAG) enhances recency and factuality in answers. However, existing evaluations rarely test how well these systems cope with real-world noise, conflicting between internal and external retrieved contexts, or…

Computation and Language · Computer Science 2025-10-29 Yixiao Zeng , Tianyu Cao , Danqing Wang , Xinran Zhao , Zimeng Qiu , Morteza Ziyadi , Tongshuang Wu , Lei Li

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Detection of pathologies is a fundamental task in medical imaging and the evaluation of algorithms that can perform this task automatically is crucial. However, current object detection metrics for natural images do not reflect the specific…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Felix Meissen , Philip Müller , Georgios Kaissis , Daniel Rueckert

Large language models (LLMs) struggle with maintaining accurate knowledge due to conflicting/outdated parametric memories. While locate-and-edit methods address this, their reliance on models' internal representations leads to robustness…

Computation and Language · Computer Science 2025-05-23 Jianhao Yan , Futing Wang , Yun Luo , Yafu Li , Yue Zhang