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In this work, we present (i) a novel approach how artificial intelligence can support in the therapy for better concentration of children with Attention Deficit Hyperactivity Disorder (ADHD) through motivational attention training with a…

Human-Computer Interaction · Computer Science 2024-05-07 Birte Richter , Ira-Katharina Petras , Anna-Lisa Vollmer , Ayla Luong , Michael Siniatchkin , Britta Wrede

This paper considers making active learning more sensible from a medical perspective. In practice, a disease manifests itself in different forms across patient cohorts. Existing frameworks have primarily used mathematical constructs to…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Yash-yee Logan , Ryan Benkert , Ahmad Mustafa , Gukyeong Kwon , Ghassan AlRegib

Individuals can vary drastically in their response to the same treatment, and this heterogeneity has driven the push for more personalized medicine. Accurate and interpretable methods to identify subgroups that respond to the treatment…

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

Quantitative Methods · Quantitative Biology 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi

Invasive ductal carcinoma (IDC) is the most prevalent form of breast cancer, and early, accurate diagnosis is critical to improving patient survival rates by guiding treatment decisions. Combining medical expertise with artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shuo Han , Ahmed Karam Eldaly , Solomon Sunday Oyelere

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

In clinical trials, an experimental treatment is sometimes added on to a standard of care or control therapy in multiple treatment phases (e.g., concomitant and maintenance phases) to improve patient outcomes. When the new regimen provides…

Methodology · Statistics 2020-11-19 Sudipta Bhattacharya , Jyotirmoy Dey

The clustering performance of Fuzzy Adaptive Resonance Theory (Fuzzy ART) is highly dependent on the preset vigilance parameter, where deviations in its value can lead to significant fluctuations in clustering results, severely limiting its…

Machine Learning · Computer Science 2025-05-09 Xiaozheng Qu , Zhaochuan Li , Zhuang Qi , Xiang Li , Haibei Huang , Lei Meng , Xiangxu Meng

Objective: Tumor Treating Fields (TTFields) is an emerging approach for cancer therapy that inhibits tumor cell proliferation by applying alternating electric fields (EF) of intermediate frequency and low intensity. The TTFields-induced…

Medical Physics · Physics 2024-10-17 Minmin Wang , Xu Xie , Zhengbo Fan , Yue Lan , Yun Pan , Guangdi Chen , Shaomin Zhang , Yuxing Wang

Individual entities are being connected every day with the advancement of Internet of Things (IoT). IoT contains various application domains and healthcare is one of them indeed. It is receiving a lot of attention recently because of its…

Computers and Society · Computer Science 2024-07-31 Nishargo Nigar

An optimal dynamic treatment regime (DTR) is a sequence of decision rules aimed at providing the best course of treatments individualized to patients. While conventional DTR estimation uses longitudinal data, such data can also be…

Methodology · Statistics 2025-02-06 Larry Dong , Eleanor Pullenayegum , Rodolphe Thiébaut , Olli Saarela

Prescription contraceptives play a critical role in supporting women's reproductive health. With nearly 50 million women in the United States using contraceptives, understanding the factors that drive contraceptives selection and switching…

Computation and Language · Computer Science 2024-02-07 Brenda Y. Miao , Christopher YK Williams , Ebenezer Chinedu-Eneh , Travis Zack , Emily Alsentzer , Atul J. Butte , Irene Y. Chen

Individualized treatment rules/recommendations (ITRs) aim to improve patient outcomes by tailoring treatments to the characteristics of each individual. However, when there are many treatment groups, existing methods face significant…

Methodology · Statistics 2025-05-27 Ke Zhu , Jianing Chu , Ilya Lipkovich , Wenyu Ye , Shu Yang

There is a dearth of robust methods to estimate the causal effects of multiple treatments when the outcome is binary. This paper uses two unique sets of simulations to propose and evaluate the use of Bayesian Additive Regression Trees…

Methodology · Statistics 2020-01-22 Liangyuan Hu , Chenyang Gu , Michael Lopez , Jiayi Ji , Juan Wisnivesky

Probing signal injection is a well-established technique to extract additional information from a weakly (or non) observable dynamical system. Using averaging theory, a framework to analyse such schemes for general nonlinear systems has…

Systems and Control · Computer Science 2019-11-20 Bowen Yi , Romeo Ortega , Houria Siguerdidjane , Juan E. Machado , Weidong Zhang

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

There is a growing interest in the implementation of platform trials, which provide the flexibility to incorporate new treatment arms during the trial and the ability to halt treatments early based on lack of benefit or observed…

Methodology · Statistics 2023-08-25 Peter Greenstreet , Thomas Jaki , Alun Bedding , Pavel Mozgunov

We propose the instrumental variable regime (IVR) method to estimate the causal effects of multiple sequential treatments. This method serves to address the problem of endogenous selections of sequential treatments. An IVR is a sequence of…

Methodology · Statistics 2017-02-21 Thai Pham , Weixin Chen

Breast cancer is the most common cancer among women worldwide. The human epidermal growth factor receptor 2 (HER2) with immunohistochemical (IHC) is widely used for pathological evaluation to provide the appropriate therapy for patients…

Quantitative Methods · Quantitative Biology 2022-03-08 Zichen Zhang , Lang Wang , Shuhao Wang

Manual Pap smear analysis for cervical cancer screening is limited by inter-observer variability, time constraints, and restricted expert availability. Although convolutional neural networks (CNNs) have automated cervical cell…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nisreen Albzour , Sarah S. Lam