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Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The…

Quantitative Methods · Quantitative Biology 2019-11-12 Bo Zhang , Yuqi Cui , Meng Wang , Jingjing Li , Lei Jin , Dongrui Wu

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (IVF). In particular, AI shows significant promise in supporting decision-making during the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Jana Zakall , Birgit Pohn , Antonia Graf , Daniel Kovatchki , Arezoo Borji , Ragib Shahriar Islam , Hossam Haick , Heinz Strohmer , Sepideh Hatamikia

The process of fertilizing a human egg outside the body in order to help those suffering from infertility to conceive is known as in vitro fertilization (IVF). Despite being the most effective method of assisted reproductive technology…

A growing share of the world's population is being born via assisted reproductive technology (ART), including in-vitro fertilisation (IVF). However, two concerns persist. First, ART pregnancies correlate with predictors of poor outcomes at…

General Economics · Economics 2024-09-04 Fabio I. Martinenghi , Xian Zhang , Luk Rombauts , Georgina M. Chambers

In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to…

Applications · Statistics 2020-10-21 Jack Wilkinson , Stephen A Roberts , Andy Vail

In vitro fertilization (IVF) is a widely utilized assisted reproductive technology, yet predicting its success remains challenging due to the multifaceted interplay of clinical, demographic, and procedural factors. This study develops a…

Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial…

Machine Learning · Computer Science 2025-02-13 Byron A Jacobs , Ifthakaar Shaik , Frando Lin

Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro…

Artificial Intelligence · Computer Science 2025-09-25 Xueqiang Ouyang , Jia Wei

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary…

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nicklas Neu , Thomas Ebner , Jasmin Primus , Bernhard Schenkenfelder , Raphael Zefferer , Mathias Brunbauer , Florian Kromp

Oocyte retrieval forms a crucial part of in vitro fertilisation treatment and its ultimate outcome. Standard double-lumen needles, which include a sequence of aspiration and flushing steps, are characterised by a similar success rate to…

An important limitation to the development of Artificial Intelligence (AI)-based solutions for In Vitro Fertilization (IVF) is the absence of a public reference benchmark to train and evaluate deep learning (DL) models. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-05-16 Tristan Gomez , Magalie Feyeux , Nicolas Normand , Laurent David , Perrine Paul-Gilloteaux , Thomas Fréour , Harold Mouchère

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Zahra Asghari Varzaneh , Niclas Wölner-Hanssen , Reza Khoshkangini , Thomas Ebner , Magnus Johnsson

Infertility is becoming an issue for an increasing number of couples. The most common solution, in vitro fertilization, requires embryologists to carefully examine light microscopy images of human oocytes to determine their developmental…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Denis Baručić , Jan Kybic , Olga Teplá , Zinovij Topurko , Irena Kratochvílová

Macroscopic, phenomenological models have proven useful as concise framings of our understandings in fields from statistical physics to economics to biology. Constructing a phenomenological model for development would provide a framework…

Cell Behavior · Quantitative Biology 2021-03-24 Brian D Leahy , Catherine Racowsky , Daniel Needleman

Individualized treatment rules (ITRs) are considered a promising recipe to deliver better policy interventions. One key ingredient in optimal ITR estimation problems is to estimate the average treatment effect conditional on a subject's…

Methodology · Statistics 2021-03-16 Hongming Pu , Bo Zhang

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Ali Akbar Septiandri , Ade Jamal , Pritta Ameilia Iffanolida , Oki Riayati , Budi Wiweko

An important limitation to the development of AI-based solutions for In Vitro Fertilization (IVF) is the black-box nature of most state-of-the-art models, due to the complexity of deep learning architectures, which raises potential bias and…

Computer Vision and Pattern Recognition · Computer Science 2022-05-16 Tristan Gomez , Thomas Fréour , Harold Mouchère
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