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Cervical cancer is one of the most severe diseases threatening women's health. Early detection and diagnosis can significantly reduce cancer risk, in which cervical cytology classification is indispensable. Researchers have recently…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Linyi Qian , Qian Huang , Yulin Chen , Junzhou Chen

A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

AI-enabled decision-support systems aim to help medical providers rapidly make decisions with limited information during medical emergencies. A critical challenge in developing these systems is supporting providers in interpreting the…

Cancer is one of the leading health challenges for women, specifically breast and ovarian cancer. Early detection can help improve the survival rate through timely intervention and treatment. Traditional methods of detecting cancer involve…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Richa Rawat , Faisal Ahmed

Combination Antiretroviral Therapy (cART) succeeds to control viral replication in most HIV infected patients. This is normally followed by a reconstitution of the CD4$^+$ T cells pool; however, this does not happen for a substantial…

Applications · Statistics 2016-02-18 Ana Jarne , Daniel Commenges , Mélanie Prague , Yves Levy , Rodolphe Thiébaut

In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

Surgical emergencies often trigger acute cognitive overload in novice physicians, impairing their decision-making under pressure. Although Virtual Reality-based Stress Inoculation Training (VR-SIT) shows promise, current systems fall short…

Human-Computer Interaction · Computer Science 2026-01-27 Shuhao Zhang , Jiahe Dong , Haoran Wang , Chang Jiang , Quan Li

In ophthalmology, intravitreal operative medication therapy (IVOM) is a widespread treatment for diseases related to the age-related macular degeneration (AMD), the diabetic macular edema (DME), as well as the retinal vein occlusion (RVO).…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Tobias Schlosser , Frederik Beuth , Trixy Meyer , Arunodhayan Sampath Kumar , Gabriel Stolze , Olga Furashova , Katrin Engelmann , Danny Kowerko

Volumetric Modulated Arc Therapy (VMAT) is a cornerstone of modern radiation therapy, enabling highly conformal tumor irradiation and healthy-tissue sparing. Yet, its planning solves inverse and nested optimization for multi-leaf…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Isabella Poles , Simon Arberet , Riqiang Gao , Martin Kraus , Marco D. Santambrogio , Florin C. Ghesu , Ali Kamen , Dorin Comaniciu

In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically…

Individualized treatment rules (ITR) can improve health outcomes by recognizing that patients may respond differently to treatment and assigning therapy with the most desirable predicted outcome for each individual. Flexible and efficient…

Methodology · Statistics 2017-09-25 Brent R. Logan , Rodney Sparapani , Robert E. McCulloch , Purushottam W. Laud

Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…

Human-Computer Interaction · Computer Science 2024-08-08 Siyi Wu , Weidan Cao , Shihan Fu , Bingsheng Yao , Ziqi Yang , Changchang Yin , Varun Mishra , Daniel Addison , Ping Zhang , Dakuo Wang

Complementary and alternative medicine are commonly used concomitantly with conventional medications leading to adverse drug reactions and even fatality in some cases. Furthermore, the vast possibility of herb-drug interactions prevents…

Artificial Intelligence · Computer Science 2023-06-28 Andreia Martins , Eva Maia , Isabel Praça

Biology has changed radically in the last two decades, transitioning from a descriptive science into a design science. Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or…

Quantitative Methods · Quantitative Biology 2021-01-27 Tijana Radivojević , Zak Costello , Kenneth Workman , Hector Garcia Martin

Applying state-of-the-art machine learning and natural language processing on approximately one million of teleconsultation records, we developed a triage system, now certified and in use at the largest European telemedicine provider. The…

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

This paper explores the use of deep learning-based computer vision for real-time monitoring of the flow in intravenous (IV) infusions. IV infusions are among the most common therapies in hospitalized patients and, given that both…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Nicola Giaquinto , Marco Scarpetta , Maurizio Spadavecchia , Gregorio Andria

Dynamic treatment regimes formalize precision medicine as a sequence of decision rules, one for each stage of clinical intervention, that map current patient information to a recommended intervention. Optimal regimes are typically defined…

Methodology · Statistics 2024-07-09 Kyle Duke , Eric B. Laber , Marie Davidian , Michael Newcomb , Brian Mustanksi

Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile,…

Machine Learning · Computer Science 2019-03-25 Ashkan Sharabiani , Adam Bress , William Galanter , Rezvan Nazempour , Houshang Darabi

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

Machine Learning · Computer Science 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold