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We investigate and characterize the performance of an important class of operations on GPUs and Many Integrated Core (MIC) architectures. Our work is motivated by applications that analyze low-dimensional spatial datasets captured by high…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-11-05 George Teodoro , Tahsin Kurc , Jun Kong , Lee Cooper , Joel Saltz

Computational neuroscience is being revolutionized with the advent of multi-electrode arrays that provide real-time, dynamic, perspectives into brain function. Mining event streams from these chips is critical to understanding the firing…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-05-15 Yong Cao , Debprakash Patnaik , Sean Ponce , Jeremy Archuleta , Patrick Butler , Wu-chun Feng , Naren Ramakrishnan

Memory management across discrete CPU and GPU physical memory is traditionally achieved through explicit GPU allocations and data copy or unified virtual memory. The Grace Hopper Superchip, for the first time, supports an integrated CPU-GPU…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-11 Gabin Schieffer , Jacob Wahlgren , Jie Ren , Jennifer Faj , Ivy Peng

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

Machine Learning · Computer Science 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

Gene-gene interactions play a crucial role in the manifestation of complex human diseases. Uncovering significant gene-gene interactions is a challenging task. Here, we present an innovative approach utilizing data-driven computational…

Artificial Intelligence · Computer Science 2024-10-22 Yifan Wu , Yuntao Yang , Zirui Liu , Zhao Li , Khushbu Pahwa , Rongbin Li , Wenjin Zheng , Xia Hu , Zhaozhuo Xu

Structural parameters are normally extracted from observed galaxies by fitting analytic light profiles to the observations. Obtaining accurate fits to high-resolution images is a computationally expensive task, requiring many model…

Instrumentation and Methods for Astrophysics · Physics 2015-03-17 Benjamin R. Barsdell , David G. Barnes , Christopher J. Fluke

Serious games and gamification (SGG) have shown to have positive effects on health outcomes of eHealth applications. However, research has shown that a shift towards a personalized approach is needed, considering the diversity of users.…

Human-Computer Interaction · Computer Science 2026-03-31 Stéphanie Carlier , Femke De Backere , Filip De Turck

Understanding the relationships between different properties of data, such as whether a connectome or genome has information about disease status, is becoming increasingly important in modern biological datasets. While existing approaches…

Machine Learning · Statistics 2024-06-27 Joshua T. Vogelstein , Eric Bridgeford , Qing Wang , Carey E. Priebe , Mauro Maggioni , Cencheng Shen

Graphics Processing Unit, or GPUs, have been successfully adopted both for graphic computation in 3D applications, and for general purpose application (GP-GPUs), thank to their tremendous performance-per-watt. Recently, there is a big…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-03 Paolo Burgio

Heterogeneous processors with architecturally different cores (CPU and GPU) integrated on the same die lead to new challenges and opportunities for thermal and power management techniques because of shared thermal/power budgets between…

Hardware Architecture · Computer Science 2018-08-30 Kapil Dev , Indrani Paul , Wei Huang , Yasuko Eckert , Wayne Burleson , Sherief Reda

The reliance of organisations on computer networks is enabled by network programmability, which is typically achieved through Service Function Chaining. These chains virtualise network functions, link them, and programmatically embed them…

Neural and Evolutionary Computing · Computer Science 2025-12-11 Theviyanthan Krishnamohan , Lauritz Thamsen , Paul Harvey

Genetic Algorithms (GAs) are used to solve search and optimization problems in which an optimal solution can be found using an iterative process with probabilistic and non-deterministic transitions. However, depending on the problem's…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-23 Matheus F. Torquato , Marcelo A. C. Fernandes

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

A bioinformatics platform is introduced aimed at identifying models of disease-specific pathways, as well as a set of network measures that can quantify changes in terms of global structure or single link disruptions.The approach integrates…

Molecular Networks · Quantitative Biology 2012-01-17 A. Barla , S. Riccadonna , S. Masecchia , M. Squillario , M. Filosi , G. Jurman , C. Furlanello

CPU-GPU heterogeneous systems are now commonly used in HPC (High-Performance Computing). However, improving the utilization and energy-efficiency of such systems is still one of the most critical issues. As one single program typically…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-08 Eishi Arima , Minjoon Kang , Issa Saba , Josef Weidendorfer , Carsten Trinitis , Martin Schulz

Matrix multiplication is a foundational operation in scientific computing and machine learning, yet its computational complexity makes it a significant bottleneck for large-scale applications. The shift to parallel architectures, primarily…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-30 Mufakir Qamar Ansari , Mudabir Qamar Ansari

Neurological and Physiological Disorders that impact emotional regulation each have their own unique characteristics which are important to understand in order to create a generalized solution to all of them. The purpose of this experiment…

Human-Computer Interaction · Computer Science 2024-11-25 Vedant Mehta

In the field of brain-computer interface (BCI) research, the availability of high-quality open-access datasets is essential to benchmark the performance of emerging algorithms. The existing open-access datasets from past competitions mostly…

Human-Computer Interaction · Computer Science 2021-10-29 Anirban Chowdhury , Javier Andreu-Perez

Cellular response to a perturbation is the result of a dynamic system of biological variables linked in a complex network. A major challenge in drug and disease studies is identifying the key factors of a biological network that are…

Applications · Statistics 2014-09-02 Lisa M. Pham , Luis Carvalho , Scott Schaus , Eric D. Kolaczyk

Epistasis is a phenomenon in which a phenotype outcome is determined by the interaction of genetic variation at two or more loci and it cannot be attributed to the additive combination of effects corresponding to the individual loci.…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-03 Christian Ponte-Fernández , Jorge González-Domínguez , María J. Martín