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In this paper, to unveil interpretable development-specific gene signatures in human PFC, we propose a novel gene selection method, named Interpretable Causality Gene Selection (ICGS), which adopts a Bayesian Network (BN) to represent…

Neurons and Cognition · Quantitative Biology 2022-11-18 Meng Huang , Xiucai Ye , Tetsuya Sakurai

Epilepsy is a chronic neurological disorder with a significant prevalence. However, there is still no adequate technological support to enable epilepsy detection and continuous outpatient monitoring in everyday life. Hyperdimensional (HD)…

Neural and Evolutionary Computing · Computer Science 2024-04-30 Una Pale , Tomas Teijeiro , David Atienza

Graph partitioning, a well studied problem of parallel computing has many applications in diversified fields such as distributed computing, social network analysis, data mining and many other domains. In this paper, we introduce FGPGA, an…

Neural and Evolutionary Computing · Computer Science 2014-11-18 Md. Lisul Islam , Novia Nurain , Swakkhar Shatabda , M Sohel Rahman

Cancer is a highly heterogeneous disease with significant variability in molecular features and clinical outcomes, making diagnosis and treatment challenging. In recent years, high-throughput omic technologies have facilitated the discovery…

Quantitative Methods · Quantitative Biology 2024-08-19 Saiful Islam , Md. Nahid Hasan

To assess how future progress in gravitational microlensing computation at high optical depth will rely on both hardware and software solutions, we compare a direct inverse ray-shooting code implemented on a graphics processing unit (GPU)…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 N. F. Bate , C. J. Fluke , B. R. Barsdell , H. Garsden , G. F. Lewis

Graphics Processing Units (GPUs) are a ubiquitous component across the range of today's computing platforms, from phones and tablets, through personal computers, to high-end server class platforms. With the increasing importance of graphics…

Cryptography and Security · Computer Science 2020-11-20 Sankha Baran Dutta , Hoda Naghibijouybari , Nael Abu-Ghazaleh , Andres Marquez , Kevin Barker

Detecting the interactions of genetic compounds like genes, SNPs, proteins, metabolites, etc. can potentially unravel the mechanisms behind complex traits and common genetic disorders. Several methods have been taken into consideration for…

Computational Engineering, Finance, and Science · Computer Science 2015-05-26 Francesco Gadaleta

This work illustrates potentials for recognition within {\em ad hoc} sensor networks if their nodes possess individual inter-related biologically inspired genetic codes. The work takes ideas from natural immune systems protecting organisms…

Cryptography and Security · Computer Science 2009-12-31 Reinert Korsnes , Knut Ovsthus

Genetic algorithms have played an important role in engineering optimization. Traditional GAs treat each gene separately. However, biophysical studies of gene regulatory networks revealed direct associations between different genes. It…

Neural and Evolutionary Computing · Computer Science 2024-05-01 Zhaoning Shi , Meng Xiang , Zhaoyang Hai , Xiabi Liu , Yan Pei

Progress in Whole Genome Sequencing (WGS) will soon allow a large number of individuals to have their genome fully sequenced. This lays the foundations to improve modern healthcare, enabling a new era of personalized medicine where…

Cryptography and Security · Computer Science 2014-02-03 Emiliano De Cristofaro

Genetic Programming (GP), an evolutionary learning technique, has multiple applications in machine learning such as curve fitting, data modelling, feature selection, classification etc. GP has several inherent parallel steps, making it an…

Neural and Evolutionary Computing · Computer Science 2021-10-22 Vimarsh Sathia , Venkataramana Ganesh , Shankara Rao Thejaswi Nanditale

This article features extended summaries and retrospectives of some of the recent research done by our research group, SAFARI, on (1) various critical problems in memory systems and (2) how memory system bottlenecks affect graphics…

Hardware Architecture · Computer Science 2018-05-30 Onur Mutlu , Saugata Ghose , Rachata Ausavarungnirun

Precision medicine aims to create biomedical solutions tailored to specific factors that affect disease risk and treatment responses within the population. The success of the genomics era and recent widespread availability of electronic…

Other Quantitative Biology · Quantitative Biology 2024-02-27 Ruth Johnson , Bogdan Pasaniuc

Smart and IoT-enabled mobile devices have the potential to enhance healthcare services for both patients and healthcare providers. Human computer interaction design is key to realizing a useful and usable connection between the users and…

Human-Computer Interaction · Computer Science 2020-02-26 Pu Liu , Sidney Fels , Nicholas West , Matthias Görges

Identifying genes associated with complex human diseases is one of the main challenges of human genetics and computational medicine. To answer this question, millions of genetic variants get screened to identify a few of importance. To…

Genomics · Quantitative Biology 2015-09-01 Aziz M. Mezlini , Fabio Fuligni , Adam Shlien , Anna Goldenberg

We investigate the problem of exact set similarity joins using a co-process CPU-GPU scheme. The state-of-the-art CPU solutions split the wok in two main phases. First, filtering and index building takes place to reduce the candidate sets to…

Databases · Computer Science 2018-12-24 Christos Bellas , Anastasios Gounaris

Polygenic risk scores (PRSs) can significantly enhance breast cancer risk prediction when combined with clinical risk factor data. While many studies have explored the value-add of PRSs, little is known about the potential impact of…

Genomics · Quantitative Biology 2024-07-31 Monica Isgut , Andrew Hornback , Yunan Luo , Asma Khimani , Neha Jain , May D. Wang

eHealth technologies have been increasingly used to foster proactive self-management skills for patients with chronic diseases. However, it is challenging to provide each user with their desired support due to the dynamic and diverse nature…

Human-Computer Interaction · Computer Science 2023-12-20 Wei Wang , Hourieh Khalajzadeh , Anuradha Madugalla , Jennifer Mcintosh , Humphrey Obie

Genetic Programming (GP) has been primarily used to tackle optimization, classification, and feature selection related tasks. The widespread use of GP is due to its flexible and comprehensible tree-type structure. Similarly, research is…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Asifullah Khan , Aqsa Saeed Qureshi , Noorul Wahab , Mutawara Hussain , Muhammad Yousaf Hamza

Traditional GWAS has advanced our understanding of complex diseases but often misses nonlinear genetic interactions. Deep learning offers new opportunities to capture complex genomic patterns, yet existing methods mostly depend on feature…

Machine Learning · Computer Science 2025-07-08 Iqra Farooq , Sara Atito , Ayse Demirkan , Inga Prokopenko , Muhammad Rana
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