English
Related papers

Related papers: Ab Initio Nucleic Acid Folding Simulations Using a…

200 papers

The state-of-the-art ab initio nuclear many-body approaches with modern nuclear forces are challenged by the recent experimental measurement of the monopole form factor of the $0^+_1\rightarrow 0^+_2$ transition in the $\alpha$ particle…

Nuclear Theory · Physics 2025-10-17 P. Yin , A. M. Shirokov , H. Li , B. Zhou , X. Zhao , S. Bacca , J. P. Vary

The folding of a polypeptide is an example of the cooperative effects of the amino-acid residues. Of recent interest is how a secondary structure, such as a helix, spontaneously forms during the collapse of a peptide from an initial…

Soft Condensed Matter · Physics 2016-08-31 Josh P. Kemp , Jeff Z. Y. Chen

Contact-assisted protein folding has made very good progress, but two challenges remain. One is accurate contact prediction for proteins lack of many sequence homologs and the other is that time-consuming folding simulation is often needed…

Biomolecules · Quantitative Biology 2022-10-12 Jinbo Xu

Theoretical modeling of nucleus-nucleus collision often is based on the nucleus-nucleus potential. One of the advanced methods for constructing this potential is the semi-microscopical double-folding model with the M3Y-Paris NN-forces.…

Nuclear Theory · Physics 2023-07-26 I. I. Gontchar , M. V. Chushnyakova

A central goal of protein-folding theory is to predict the stochastic dynamics of transition paths --- the rare trajectories that transit between the folded and unfolded ensembles --- using only thermodynamic information, such as a…

Biomolecules · Quantitative Biology 2018-08-09 William M. Jacobs , Eugene I. Shakhnovich

There has been significant recent progress in solving the long-standing problems of how nuclear shell structure and collective motion emerge from underlying microscopic inter-nucleon interactions. We review a selection of recent significant…

We demonstrate the existence of multiple converging sequences in the ab initio no-core shell model. By examining the underlying theory of effective operators, we expose the physical foundations for the alternative pathways to convergence.…

Nuclear Theory · Physics 2008-11-26 C. Forssén , J. P. Vary , E. Caurier , P. Navrátil

For the vast majority of naturally occurring, small, single domain proteins folding is often described as a two-state process that lacks detectable intermediates. This observation has often been rationalized on the basis of a nucleation…

Biomolecules · Quantitative Biology 2007-07-09 R. D. M. Travasso , P. F. N. Faisca , M. M. Telo da Gama

AlphaFold 3 represents a transformative advancement in computational biology, enhancing protein structure prediction through novel multi-scale transformer architectures, biologically informed cross-attention mechanisms, and geometry-aware…

Biomolecules · Quantitative Biology 2025-08-27 Alireza Abbaszadeh , Armita Shahlaee

The radiation-induced damages in bio-molecules are ubiquitous processes in radiotherapy, radio-biology and critical to space-projects. In this study we present a precise quantification of the fragmentation mechanisms of deoxyribonucleic…

Biological Physics · Physics 2022-01-28 Santosh KC , Ramin Abolfath

A new formalism for calculation of the partition function of single stranded nucleic acids is presented. Secondary structures and the topology of structure elements are the level of resolution that is used. The folding model deals with…

Biomolecules · Quantitative Biology 2007-05-23 Roumen A. Dimitrov

Extreme mechanical processes such as strong lattice distortion and bond breakage during fracture are ubiquitous in nature and engineering, which often lead to catastrophic failure of structures. However, understanding the nucleation and…

Materials Science · Physics 2024-07-23 Pengjie Shi , Zhiping Xu

Carbon dioxide hydrates are ice-like nonstoichiometric inclusion solid compounds with importance to global climate change, and gas transportation and storage. The thermodynamic and kinetic mechanisms that control carbon dioxide nucleation…

This work proposes a new efficient approach for calculating the bending stiffness of two-dimensional materials using simple atomistic tests on small periodic unit cells. The tests are designed such that bending deformations are dominating…

Materials Science · Physics 2022-12-23 Farzad Shirazian , Roger A. Sauer

We present a novel theory and implementation for computing coupled electronic and quantal nuclear subsystems on a single potential energy surface, moving beyond the standard Born-Oppenheimer (BO) separation of nuclei and electrons. We…

Chemical Physics · Physics 2021-11-15 Ziyong Chen , Jun Yang

Here we present the results from two sets of simulations, in two and three spatial dimensions. In two dimensions, the simulations include multifrequency flux-limited diffusion neutrino transport in the "ray-by-ray-plus" approximation,…

Astrophysics · Physics 2009-11-13 A. Mezzacappa , S. W. Bruenn , J. M. Blondin , W. R. Hix , O. E. B. Messer

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

Genomics · Quantitative Biology 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat

A modified version of the previously proposed exponential model with pairing attenuation for the well deformed even-even nuclei has been applied to predict the energy levels of doubly even actinide nuclei. Satisfactory results are obtained…

Nuclear Theory · Physics 2007-05-23 H. H. Alharbi , H. A. Alhendi , S. U. El-Kameesy

The study of biomolecular folding has been greatly advanced by single-molecule force spectroscopy (SMFS), which enables the observation of the dynamics of individual molecules. However, extracting quantitative models of fundamental…

Chemical Physics · Physics 2026-04-30 Lars Dingeldein , Aaron Lyons , Pilar Cossio , Michael Woodside , Roberto Covino

A feed-forward neural network is demonstrated to efficiently unfold the energy distribution of protons and alpha particles passing through passive material. This model-independent approach works with unbinned data and does not require…

High Energy Physics - Experiment · Physics 2021-12-16 Ming-Liang Wong , Andrew Edmonds , Chen Wu