English

Folding dynamics of the helical structures in a minimal model

Soft Condensed Matter 2016-08-31 v1 Statistical Mechanics q-bio

Abstract

The folding of a polypeptide is an example of the cooperative effects of the amino-acid residues. Of recent interest is how a secondary structure, such as a helix, spontaneously forms during the collapse of a peptide from an initial denatured state. The Monte Carlo implementation of a recent helix-forming model enables us to study the entire folding process dynamically. As shown by the computer simulations, the foldability and helical propagation are both strongly correlated to the nucleation properties of the sequence.

Keywords

Cite

@article{arxiv.cond-mat/0201374,
  title  = {Folding dynamics of the helical structures in a minimal model},
  author = {Josh P. Kemp and Jeff Z. Y. Chen},
  journal= {arXiv preprint arXiv:cond-mat/0201374},
  year   = {2016}
}

Comments

3 figures Submitted to Europhys Letter