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Rare cancers affect millions of people worldwide each year. However, estimating incidence or mortality rates associated with rare cancers presents important difficulties and poses new statistical methodological challenges. In this paper, we…

Methodology · Statistics 2025-07-30 Garazi Retegui , Jaione Etxeberria , María Dolores Ugarte

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Cancer data, particularly cancer incidence and mortality, are fundamental to understand the cancer burden, to set targets for cancer control and to evaluate the evolution of the implementation of a cancer control policy. However, the…

Methodology · Statistics 2025-11-27 Garazi Retegui , Jaione Etxeberria , María Dolores Ugarte

We consider the challenges that arise when fitting complex ecological models to 'large' data sets. In particular, we focus on random effect models which are commonly used to describe individual heterogeneity, often present in ecological…

Methodology · Statistics 2022-05-17 Ruth King , Blanca Sarzo , Víctor Elvira

Additive spatial statistical models with weakly stationary process assumptions have become standard in spatial statistics. However, one disadvantage of such models is the computation time, which rapidly increases with the number of data…

Methodology · Statistics 2024-10-18 Sudipto Saha , Jonathan R. Bradley

Nonstationary non-Gaussian spatial data are common in many disciplines, including climate science, ecology, epidemiology, and social sciences. Examples include count data on disease incidence and binary satellite data on cloud mask…

Computation · Statistics 2020-11-30 Benjamin Seiyon Lee , Jaewoo Park

The increasing availability of complex survey data, and the continued need for estimates of demographic and health indicators at a fine spatial and temporal scale, which leads to issues of data sparsity, has led to the need for…

Data with spatial-temporal attributes are prevalent across many research fields, and statistical models for analyzing spatio-temporal relationships are widely used. Existing reviews focus either on specific domains or model types, creating…

Applications · Statistics 2025-11-04 Isabella Habereder , Thomas Kneib , Isao Echizen , Timo Spinde

With the rapid advances of data acquisition techniques, spatio-temporal data are becoming increasingly abundant in a diverse array of disciplines. Here we develop spatio-temporal regression methodology for analyzing large amounts of…

Methodology · Statistics 2021-12-01 Ting Fung Ma , Fangfang Wang , Jun Zhu , Anthony R. Ives , Katarzyna E. Lewińska

With the advancement of GPS and remote sensing technologies, large amounts of geospatial and spatiotemporal data are being collected from various domains, driving the need for effective and efficient prediction methods. Given spatial data…

Machine Learning · Computer Science 2020-12-25 Zhe Jiang

Spatial small area estimation models have become very popular in some contexts, such as disease mapping. Data in disease mapping studies are exhaustive, that is, the available data are supposed to be a complete register of all the…

Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

This paper proposes a two-stage estimation approach for a spatial misalignment scenario that is motivated by the epidemiological problem of linking pollutant exposures and health outcomes. We use the integrated nested Laplace approximation…

Methodology · Statistics 2022-07-21 Stephen Jun Villejo , Janine B Illian , Ben Swallow

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

Applications · Statistics 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

Fitting statistical models to spatiotemporal data requires finding the right balance between imposing smoothness and following the data. In the context of p-splines, we propose a Bayesian framework for choosing the smoothing parameter which…

Applications · Statistics 2013-10-30 A. W. Bowman , L. Evers , D. Molinari , W. R. Jones , M. J. Spence

Quantifying spatial and/or temporal associations in multivariate geolocated data of different types is achievable via spatial random effects in a Bayesian hierarchical model, but severe computational bottlenecks arise when spatial…

Methodology · Statistics 2024-04-02 Michele Peruzzi , David B. Dunson

Spatiotemporal data mining (STDM) discovers useful patterns from the dynamic interplay between space and time. Several available surveys capture STDM advances and report a wealth of important progress in this field. However, STDM challenges…

Machine Learning · Computer Science 2021-04-01 Ali Hamdi , Khaled Shaban , Abdelkarim Erradi , Amr Mohamed , Shakila Khan Rumi , Flora Salim

Multivariate spatially-oriented data sets are prevalent in the environmental and physical sciences. Scientists seek to jointly model multiple variables, each indexed by a spatial location, to capture any underlying spatial association for…

Methodology · Statistics 2021-08-19 Lu Zhang , Sudipto Banerjee

The availability of geocoded health data and the inherent temporal structure of communicable diseases have led to an increased interest in statistical models and software for spatio-temporal data with epidemic features. The open source R…

Computation · Statistics 2017-05-12 Sebastian Meyer , Leonhard Held , Michael Höhle

Spatiotemporal processes have the potential to be one of the most influential factors governing how fisheries targeting sedentary species respond to harvesting. Despite this, management strategy evaluation often fails to account for space…

Populations and Evolution · Quantitative Biology 2021-09-07 Christopher D. Nottingham , Russell B. Millar