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Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Lung cancer is a major issue in worldwide public health, requiring early diagnosis using stable techniques. This work begins a thorough investigation of the use of machine learning (ML) methods for precise classification of lung cancer…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Shayli Farshchiha , Salman Asoudeh , Maryam Shavali Kuhshuri , Mehrshad Eisaeid , Mohamadreza Azadie , Saba Hesaraki

Microbeam radiation therapy (MRT) utilizes coplanar synchrotron radiation beamlets and is a proposed treatment approach for several tumour diagnoses that currently have poor clinical treatment outcomes, such as gliosarcomas. Prescription…

We present a nonparametric Bayesian method for disease subtype discovery in multi-dimensional cancer data. Our method can simultaneously analyse a wide range of data types, allowing for both agreement and disagreement between their…

Genomics · Quantitative Biology 2013-04-16 Richard S. Savage , Zoubin Ghahramani , Jim E. Griffin , Paul Kirk , David L. Wild

Gadolinium-based contrast agents (GBCAs) are central to glioma imaging but raise safety, cost, and accessibility concerns. Predicting contrast enhancement from non-contrast MRI using machine learning (ML) offers a safer alternative, as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Sajad Amiri , Shahram Taeb , Sara Gharibi , Setareh Dehghanfard , Somayeh Sadat Mehrnia , Mehrdad Oveisi , Ilker Hacihaliloglu , Arman Rahmim , Mohammad R. Salmanpour

Background: Gliomas are the most common brain tumors, which vary from low to high-grade. Despite the improvements in imaging techniques in the last decade, all parts of the tumor are not visible in these images, due to having a threshold of…

Other Quantitative Biology · Quantitative Biology 2023-09-06 Farshad Samadifam , Ehsan Ghafourian

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Despite ongoing efforts in cancer research, a fully effective treatment for glioblastoma multiforme (GBM) is still unknown. Since adoptive cell transfer immunotherapy is one of the potential cure candidates, efforts have been made to assess…

Tissues and Organs · Quantitative Biology 2025-02-26 Wiktor Jochymczyk , Urszula Foryś

Motivation: The consistent amount of different types of omics data requires novel methods of analysis and data integration. In this work we describe Regression2Net, a computational approach to analyse gene expression and methylation…

Computational Engineering, Finance, and Science · Computer Science 2015-07-06 Francesco Gadaleta , Kyrylo Bessonov

The BraTS 2021 challenge celebrates its 10th anniversary and is jointly organized by the Radiological Society of North America (RSNA), the American Society of Neuroradiology (ASNR), and the Medical Image Computing and Computer Assisted…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Ujjwal Baid , Satyam Ghodasara , Suyash Mohan , Michel Bilello , Evan Calabrese , Errol Colak , Keyvan Farahani , Jayashree Kalpathy-Cramer , Felipe C. Kitamura , Sarthak Pati , Luciano M. Prevedello , Jeffrey D. Rudie , Chiharu Sako , Russell T. Shinohara , Timothy Bergquist , Rong Chai , James Eddy , Julia Elliott , Walter Reade , Thomas Schaffter , Thomas Yu , Jiaxin Zheng , Ahmed W. Moawad , Luiz Otavio Coelho , Olivia McDonnell , Elka Miller , Fanny E. Moron , Mark C. Oswood , Robert Y. Shih , Loizos Siakallis , Yulia Bronstein , James R. Mason , Anthony F. Miller , Gagandeep Choudhary , Aanchal Agarwal , Cristina H. Besada , Jamal J. Derakhshan , Mariana C. Diogo , Daniel D. Do-Dai , Luciano Farage , John L. Go , Mohiuddin Hadi , Virginia B. Hill , Michael Iv , David Joyner , Christie Lincoln , Eyal Lotan , Asako Miyakoshi , Mariana Sanchez-Montano , Jaya Nath , Xuan V. Nguyen , Manal Nicolas-Jilwan , Johanna Ortiz Jimenez , Kerem Ozturk , Bojan D. Petrovic , Chintan Shah , Lubdha M. Shah , Manas Sharma , Onur Simsek , Achint K. Singh , Salil Soman , Volodymyr Statsevych , Brent D. Weinberg , Robert J. Young , Ichiro Ikuta , Amit K. Agarwal , Sword C. Cambron , Richard Silbergleit , Alexandru Dusoi , Alida A. Postma , Laurent Letourneau-Guillon , Gloria J. Guzman Perez-Carrillo , Atin Saha , Neetu Soni , Greg Zaharchuk , Vahe M. Zohrabian , Yingming Chen , Milos M. Cekic , Akm Rahman , Juan E. Small , Varun Sethi , Christos Davatzikos , John Mongan , Christopher Hess , Soonmee Cha , Javier Villanueva-Meyer , John B. Freymann , Justin S. Kirby , Benedikt Wiestler , Priscila Crivellaro , Rivka R. Colen , Aikaterini Kotrotsou , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Hassan Fathallah-Shaykh , Roland Wiest , Andras Jakab , Marc-Andre Weber , Abhishek Mahajan , Bjoern Menze , Adam E. Flanders , Spyridon Bakas

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Deep Learning is the newest and the current trend of the machine learning field that paid a lot of the researchers' attention in the recent few years. As a proven powerful machine learning tool, deep learning was widely used in several…

Image and Video Processing · Electrical Eng. & Systems 2020-01-27 Ali Mohammad Alqudah , Hiam Alquraan , Isam Abu Qasmieh , Amin Alqudah , Wafaa Al-Sharu

Glioblastoma (GBM) is an aggressive and fatal tumor. The infiltrative spread of GBM cells hinders the gross total resection. The residual GBM cells are significantly associated with survival and recurrence. Therefore, a theranostic method…

Applied Physics · Physics 2025-03-10 Yung-Ching Chang , Chan-Chuan Liu , Wan-Ping Chan , Yu-Long Lin , Chun-I Sze , Shiuan-Yeh Chen

Differentiating true tumor progression (TP) from treatment-related pseudoprogression (PsP) in glioblastoma remains challenging, especially at early follow-up. We present the first stage-specific, cross-sectional benchmarking of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Wenhao Guo , Golrokh Mirzaei

Overall survival (OS) time is one of the most important evaluation indices for gliomas situations. Multimodal Magnetic Resonance Imaging (MRI) scans play an important role in the study of glioma prognosis OS time. Several deep…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Wen Tang , Haoyue Zhang , Pengxin Yu , Han Kang , Rongguo Zhang

Automatic segmentation of breast tumors from the ultrasound images is essential for the subsequent clinical diagnosis and treatment plan. Although the existing deep learning-based methods have achieved significant progress in automatic…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Xing Yang , Jian Zhang , Qijian Chen , Li Wang , Lihui Wang

Early detection of brain metastases (BM) is one of the determining factors for the successful treatment of patients with cancer; however, the accurate detection of small BM lesions (< 15mm) remains a challenging task. We previously…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Engin Dikici , Xuan V. Nguyen , Matthew Bigelow , Luciano M. Prevedello

Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Azam Hamidinekoo , Tomasz Pieciak , Maryam Afzali , Otar Akanyeti , Yinyin Yuan