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A method is presented for the distributed computation of persistent homology, based on an extension of the generalized Mayer-Vietoris principle to filtered spaces. Cellular cosheaves and spectral sequences are used to compute global…

Algebraic Topology · Mathematics 2023-08-11 Iris H. R. Yoon , Robert Ghrist

Let $K$ be a finite simplicial, cubical, delta or CW complex. The persistence map $\mathrm{PH}$ takes a filter $f:K \rightarrow \mathbb{R}$ as input and returns the barcodes $\mathrm{PH}(f)$ of the associated sublevel set persistent…

Computational Geometry · Computer Science 2021-10-29 Jacob Leygonie , Gregory Henselman-Petrusek

Early detection and analysis of calcifications in mammogram images is crucial in a breast cancer diagnosis workflow. Management of calcifications that require immediate follow-up and further analyzing its benignancy or malignancy can result…

Image and Video Processing · Electrical Eng. & Systems 2022-12-12 Adarsh Bhandary Panambur , Prathmesh Madhu , Andreas Maier

Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Yu-Min Chung , Chuan-Shen Hu , Austin Lawson , Clifford Smyth

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Yang Luo , Shiru Wang , Jun Liu , Jiaxuan Xiao , Rundong Xue , Zeyu Zhang , Hao Zhang , Yu Lu , Yang Zhao , Yutong Xie

Topological Data Analysis (TDA) combines computational topology and data science to extract and analyze intrinsic topological and geometric structures in data set in a metric space. While the persistent homology (PH), a widely used tool in…

Computational Geometry · Computer Science 2025-04-15 Chuanshen Hu , Yu Wang , Kelin Xia , Ke Ye , Yipeng Zhang

Persistent topological properties of an image serve as an additional descriptor providing an insight that might not be discovered by traditional neural networks. The existing research in this area focuses primarily on efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Ekaterina Khramtsova , Guido Zuccon , Xi Wang , Mahsa Baktashmotlagh

Topological data analysis (TDA) uses persistent homology to quantify loops and higher-dimensional holes in data, making it particularly relevant for examining the characteristics of images of cells in the field of cell biology. In the…

Methodology · Statistics 2024-05-06 Susan Glenn , Jessi Cisewski-Kehe , Jun Zhu , William M. Bement

In real-world systems, the relationships and connections between components are highly complex. Real systems are often described as networks, where nodes represent objects in the system and edges represent relationships or connections…

Algebraic Topology · Mathematics 2024-06-24 Shen Zhang

Proposing scoring functions to effectively understand, analyze and learn various properties of high dimensional hidden representations of large-scale transformer models like BERT can be a challenging task. In this work, we explore a new…

Machine Learning · Computer Science 2022-11-01 Jatin Chauhan , Manohar Kaul

Persistent homology provides a robust methodology to infer topological structures from point cloud data. Here we explore the persistent homology of point clouds embedded into a probabilistic setting, exploiting the theory of point…

Probability · Mathematics 2023-08-07 Daniel Spitz , Anna Wienhard

Point-cloud persistent homology (PH) -- computing alpha or Rips complexes on spin-position point clouds -- has been widely applied to detect phase transitions in classical spin models since Donato et al. (2016), with subsequent studies…

Statistical Mechanics · Physics 2026-04-01 Matthew Loftus

We develop an analysis pipeline for characterizing the topology of large scale structure and extracting cosmological constraints based on persistent homology. Persistent homology is a technique from topological data analysis that quantifies…

Cosmology and Nongalactic Astrophysics · Physics 2021-06-14 Matteo Biagetti , Alex Cole , Gary Shiu

Link prediction (LP), inferring the connectivity between nodes, is a significant research area in graph data, where a link represents essential information on relationships between nodes. Although graph neural network (GNN)-based models…

Machine Learning · Computer Science 2025-12-12 Junwon You , Eunwoo Heo , Jae-Hun Jung

Biomolecular structure comparison not only reveals evolutionary relationships, but also sheds light on biological functional properties. However, traditional definitions of structure or sequence similarity always involve superposition or…

Quantitative Methods · Quantitative Biology 2017-07-13 Kelin Xia

The Hough transform is a popular and classical technique in computer vision for the detection of lines (or more general objects). It maps a pixel into a dual space -- the Hough space: each pixel is mapped to the set of lines through this…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Johannes Ferner , Stefan Huber , Saverio Messineo , Angel Pop , Martin Uray

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

A topological shape analysis is proposed and utilized to learn concepts that reflect shape commonalities. Our approach is two-fold: i) a spatial topology analysis of point cloud segment constellations within objects. Therein constellations…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Christian A. Mueller , Andreas Birk

The persistent homology transform (PHT) represents a shape with a multiset of persistence diagrams parameterized by the sphere of directions in the ambient space. In this work, we describe a finite set of diagrams that discretize the PHT…

Computational Geometry · Computer Science 2026-05-26 Brittany Terese Fasy , Samuel Micka , David L. Millman , Anna Schenfisch , Lucia Williams

Determining whether two graphs are isomorphic is a fundamental problem with practical applications in areas such as molecular chemistry or social network analysis, yet it remains a challenging task, with exact solutions often being…