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Topological data analysis and its main method, persistent homology, provide a toolkit for computing topological information of high-dimensional and noisy data sets. Kernels for one-parameter persistent homology have been established to…

Machine Learning · Computer Science 2019-06-06 René Corbet , Ulderico Fugacci , Michael Kerber , Claudia Landi , Bei Wang

Persistent homology is a method for probing topological properties of point clouds and functions. The method involves tracking the birth and death of topological features (2000) as one varies a tuning parameter. Features with short…

Recent years have witnessed an increased interest in the application of persistent homology, a topological tool for data analysis, to machine learning problems. Persistent homology is known for its ability to numerically characterize the…

Neural and Evolutionary Computing · Computer Science 2016-08-29 Jen-Yu Liu , Shyh-Kang Jeng , Yi-Hsuan Yang

Characterization of medium-range order in amorphous materials and its relation to short-range order is discussed. A new topological approach is presented here to extract a hierarchical structure of amorphous materials, which is robust…

Soft Condensed Matter · Physics 2015-02-27 Takenobu Nakamura , Yasuaki Hiraoka , Akihiko Hirata , Emerson G. Escolar , Yasumasa Nishiura

In topological data analysis, persistent homology is used to study the "shape of data". Persistent homology computations are completely characterized by a set of intervals called a bar code. It is often said that the long intervals…

Computational Geometry · Computer Science 2025-02-19 Peter Bubenik , Michael Hull , Dhruv Patel , Benjamin Whittle

We present a machine learning approach that leverages persistent homology to classify bacterial flagellar motors into two functional states: rotated and stalled. By embedding protein structural data into a topological framework, we extract…

Biomolecules · Quantitative Biology 2025-12-19 Zakaria Lamine , Abdelatif Hafid , Mohamed Rahouti

In this study, we present a novel molecular fingerprint generation method based on multiparameter persistent homology. This approach reveals the latent structures and relationships within molecular geometry, and detects topological features…

Biomolecules · Quantitative Biology 2023-11-21 Andac Demir , Bulent Kiziltan

Topological data analysis (TDA) is a rising branch in modern applied mathematics. It extracts topological structures as features of a given space and uses these features to analyze digital data. Persistent homology, one of the central tools…

Algebraic Topology · Mathematics 2025-05-26 Chuan-Shen Hu

Breast cancer is becoming pervasive with each passing day. Hence, its early detection is a big step in saving the life of any patient. Mammography is a common tool in breast cancer diagnosis. The most important step here is classification…

Computer Vision and Pattern Recognition · Computer Science 2018-01-04 Aditya A. Shastri , Deepti Tamrakar , Kapil Ahuja

Dimensionality reduction is an integral part of data visualization. It is a process that obtains a structure preserving low-dimensional representation of the high-dimensional data. Two common criteria can be used to achieve a dimensionality…

Computational Geometry · Computer Science 2018-06-25 Lin Yan , Yaodong Zhao , Paul Rosen , Carlos Scheidegger , Bei Wang

Topological data analysis is a recent and fast growing field that approaches the analysis of datasets using techniques from (algebraic) topology. Its main tool, persistent homology (PH), has seen a notable increase in applications in the…

Algebraic Topology · Mathematics 2021-11-17 Renata Turkeš , Jannes Nys , Tim Verdonck , Steven Latré

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Persistent homology is a topological data analysis tool that has been widely generalized, extending its scope beyond the field of topology. Among its extensions, steady and ranging persistence were developed to study a wide variety of graph…

Algebraic Topology · Mathematics 2026-05-15 Yann-Situ Gazull

Persistence diagrams have been widely used to quantify the underlying features of filtered topological spaces in data visualization. In many applications, computing distances between diagrams is essential; however, computing these distances…

Computational Geometry · Computer Science 2021-08-12 Yu Qin , Brittany Terese Fasy , Carola Wenk , Brian Summa

As the field of Topological Data Analysis continues to show success in theory and in applications, there has been increasing interest in using tools from this field with methods for machine learning. Using persistent homology, specifically…

Computational Geometry · Computer Science 2020-02-26 Sarah Tymochko , Elizabeth Munch , Firas A. Khasawneh

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Existing interpretability methods for Large Language Models (LLMs) predominantly capture linear directions or isolated features. This overlooks the high-dimensional, relational, and nonlinear geometry of model representations. We apply…

Machine Learning · Computer Science 2026-04-27 Aideen Fay , Inés García-Redondo , Qiquan Wang , Haim Dubossarsky , Anthea Monod

The persistence barcode is a topological descriptor of data that plays a fundamental role in topological data analysis. Given a filtration of data, the persistence barcode tracks the evolution of its homology groups. In this paper, we…

Computational Geometry · Computer Science 2025-10-14 Tao Hou , Salman Parsa , Bei Wang

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

Recently a new feature representation and data analysis methodology based on a topological tool called persistent homology (and its corresponding persistence diagram summary) has started to attract momentum. A series of methods have been…

Computational Geometry · Computer Science 2019-12-13 Qi Zhao , Yusu Wang