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Junctions in the retinal vasculature are key points to be able to extract its topology, but they vary in appearance, depending on vessel density, width and branching/crossing angles. The complexity of junction patterns is usually…

Image and Video Processing · Electrical Eng. & Systems 2018-09-06 Fatmatulzehra Uslu , Anil Anthony Bharath

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Art technological investigations of historical panel paintings rely on acquiring multi-modal image data, including visual light photography, infrared reflectography, ultraviolet fluorescence photography, x-radiography, and macro…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Aline Sindel , Andreas Maier , Vincent Christlein

Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…

Tissues and Organs · Quantitative Biology 2020-02-11 Astrid M. E. Engberg , Vedrana A. Dahl , Anders B. Dahl

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Automatic analysis of retinal blood images is of vital importance in diagnosis tasks of retinopathy. Segmenting vessels accurately is a fundamental step in analysing retinal images. However, it is usually difficult due to various imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Yishuo Zhang , Albert C. S. Chung

Segmentation of retinal vessels from retinal fundus images is the key step in the automatic retinal image analysis. In this paper, we propose a new unsupervised automatic method to segment the retinal vessels from retinal fundus images.…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Renoh Johnson Chalakkal , Waleed Abdulla

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

In order to estimate a registration model of eye fundus images made of an affinity and two radial distortions, we introduce an estimation criterion based on an error between the vessels. In [1], we estimated this model by minimising the…

Medical Physics · Physics 2019-07-22 Guillaume Noyel , R Thomas , S Iles , G Bhakta , A Crowder , D. Owens , P. Boyle

Retinal diseases are a leading cause of vision impairment and blindness, with timely diagnosis being critical for effective treatment. Optical Coherence Tomography (OCT) has become a standard imaging modality for retinal disease diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Jilan Cheng , Guoli Long , Zeyu Zhang , Zhenjia Qi , Hanyu Wang , Libin Lu , Shuihua Wang , Yudong Zhang , Jin Hong

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

Multimodal registration is a challenging problem in medical imaging due the high variability of tissue appearance under different imaging modalities. The crucial component here is the choice of the right similarity measure. We make a step…

Computer Vision and Pattern Recognition · Computer Science 2016-09-20 Martin Simonovsky , Benjamín Gutiérrez-Becker , Diana Mateus , Nassir Navab , Nikos Komodakis

Retinal Optical Coherence Tomography (OCT), a noninvasive cross-sectional scan of the eye with qualitative 3D visualization of the retinal anatomy is use to study the retinal structure and the presence of pathogens. The advent of the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner

Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that provides high-resolution cross-sectional images of the retina, which are useful for diagnosing and monitoring various retinal diseases. However, manual…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Can Koz , Onat Dalmaz , Mertay Dayanc

Early and accurate classification of retinal diseases is critical to counter vision loss and for guiding clinical management of retinal diseases. In this study, we proposed a deep learning method for retinal disease classification utilizing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Mohammad Tahmid Noor , Shayan Abrar , Jannatul Adan Mahi , Md Parvez Mia , Asaduzzaman Hridoy , Samanta Ghosh

Image registration techniques usually assume that the images to be registered are of a certain type (e.g. single- vs. multi-modal, 2D vs. 3D, rigid vs. deformable) and there lacks a general method that can work for data under all…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Quang Luong Nhat Nguyen , Ruiming Cao , Laura Waller

Automated segmentation of retinal optical coherence tomography (OCT) images has become an important recent direction in machine learning for medical applications. We hypothesize that the anatomic structure of layers and their high-frequency…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Azade Farshad , Yousef Yeganeh , Peter Gehlbach , Nassir Navab

Analysis of retinal fundus images is essential for eye-care physicians in the diagnosis, care and treatment of patients. Accurate fundus and/or retinal vessel maps give rise to longitudinal studies able to utilize multimedia image…

Computer Vision and Pattern Recognition · Computer Science 2019-12-02 Henry A Leopold , Jeff Orchard , John S Zelek , Vasudevan Lakshminarayanan