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Correlating neuropathology with neuroimaging findings provides a multiscale view of pathologic changes in the human organ spanning the meso- to micro-scales, and is an emerging methodology expected to shed light on numerous disease states.…

Machine Learning · Computer Science 2024-06-07 Yifeng Wang , Weipeng Li , Thomas Pearce , Haohan Wang

Corneal endothelial cell segmentation plays a vital role inquantifying clinical indicators such as cell density, coefficient of variation,and hexagonality. However, the corneal endothelium's uneven reflectionand the subject's tremor and…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Yinglin Zhang , Risa Higashita , Huazhu Fu , Yanwu Xu , Yang Zhang , Haofeng Liu , Jian Zhang , Jiang Liu

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

This paper presents Deep Retinal Image Understanding (DRIU), a unified framework of retinal image analysis that provides both retinal vessel and optic disc segmentation. We make use of deep Convolutional Neural Networks (CNNs), which have…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Kevis-Kokitsi Maninis , Jordi Pont-Tuset , Pablo Arbeláez , Luc Van Gool

The morphology of blood vessels in retinal fundus images is an important indicator of diseases like glaucoma, hypertension and diabetic retinopathy. The accuracy of retinal blood vessels segmentation affects the quality of retinal image…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 A. M. R. R. Bandara , P. W. G. R. M. P. B. Giragama

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Retinal vessel segmentation is a vital early detection method for several severe ocular diseases. Despite significant progress in retinal vessel segmentation with the advancement of Neural Networks, there are still challenges to overcome.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Shuang Zeng , Chee Hong Lee , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Lei Zhu , Hangzhou He , Xinliang Zhang , Qian Chen , May D. Wang , Yanye Lu , Qiushi Ren

Chromosome classification is critical for karyotyping in abnormality diagnosis. To expedite the diagnosis, we present a novel method named Varifocal-Net for simultaneous classification of chromosome's type and polarity using deep…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Yulei Qin , Juan Wen , Hao Zheng , Xiaolin Huang , Jie Yang , Ning Song , Yue-Min Zhu , Lingqian Wu , Guang-Zhong Yang

Fundus photography and Optical Coherence Tomography Angiography (OCT-A) are two commonly used modalities in ophthalmic imaging. With the development of deep learning algorithms, fundus image processing, especially retinal vessel…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Weilin Fu , Lennart Husvogt , Stefan Ploner James G. Fujimoto Andreas Maier

Accurate segmentation of retinal images plays a crucial role in aiding ophthalmologists in diagnosing retinopathy of prematurity (ROP) and assessing its severity. However, due to their underdeveloped, thinner vessels, manual annotation in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Gozde Merve Demirci , Jiachen Yao , Ming-Chih Ho , Xiaoling Hu , Wei-Chi Wu , Chao Chen , Chia-Ling Tsai

Retinal fundus images can be an invaluable diagnosis tool for screening epidemic diseases like hypertension or diabetes. And they become especially useful when the arterioles and venules they depict are clearly identified and annotated.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Retinal vessel segmentation methods based on standard overlap losses tend to miss thin peripheral vessels because these structures occupy very few pixels and have low contrast against the background. We propose HMS-VesselNet, a hierarchical…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Amarnath R

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

Enhancement, followed by segmentation, quantification and modelling, of blood vessels in retinal images plays an essential role in computer-aid retinopathy diagnosis. In this paper, we introduce a new vessel enhancement method which is the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Çiğdem Sazak , Carl J. Nelson , Boguslaw Obara

With development of information technology and necessity for high security, using different identification methods has become very important. Each biometric feature has its own advantages and disadvantages and choosing each of them depends…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Ali Noori

Automated detection of curvilinear structures, e.g., blood vessels or nerve fibres, from medical and biomedical images is a crucial early step in automatic image interpretation associated to the management of many diseases. Precise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Lei Mou , Yitian Zhao , Huazhu Fu , Yonghuai Liu , Jun Cheng , Yalin Zheng , Pan Su , Jianlong Yang , Li Chen , Alejandro F Frang , Masahiro Akiba , Jiang Liu

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Peng Liu , Ruogu Fang
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