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Advances in single-cell sequencing have enabled high-resolution profiling of diverse molecular modalities, while integrating unpaired multi-omics single-cell data remains challenging. Existing approaches either rely on pair information or…

Quantitative Methods · Quantitative Biology 2026-01-21 Jianle Sun , Chaoqi Liang , Ran Wei , Peng Zheng , Lei Bai , Wanli Ouyang , Hongliang Yan , Peng Ye

Generic matrix multiplication (GEMM) and one-dimensional convolution/cross-correlation (CONV) kernels often constitute the bulk of the compute- and memory-intensive processing within image/audio recognition and matching systems. We propose…

Multimedia · Computer Science 2014-11-12 Mohammad Ashraful Anam , Paul N. Whatmough , Yiannis Andreopoulos

Objective. The main goal of this work is to develop a model for multi-sensor signals such as MEG or EEG signals, that accounts for the inter-trial variability, suitable for corresponding binary classification problems. An important…

Neurons and Cognition · Quantitative Biology 2015-06-26 J Spinnato , M-C Roubaud , B Burle , B Torrésani

A number of statistical models have been successfully developed for the analysis of high-throughput data from a single source, but few methods are available for integrating data from different sources. Here we focus on integrating gene…

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li

In cryo-electron microscopy (EM), molecular structures are determined from large numbers of projection images of individual particles. To harness the full power of this single-molecule information, we use the Bayesian inference of EM…

Biomolecules · Quantitative Biology 2018-01-17 Pilar Cossio , David Rohr , Fabio Baruffa , Markus Rampp , Volker Lindenstruth , Gerhard Hummer

In this paper we describe a new methodology to calculate analytically the error for a maximum likelihood estimate (MLE) for physical parameters from Gravitational wave signals. All the existing litterature focuses on the usage of the Cramer…

General Relativity and Quantum Cosmology · Physics 2011-08-15 Michele Zanolin , Salvatore Vitale , Nicholas Makris

Detection limit (DL) has become an increasingly ubiquitous issue in statistical analyses of biomedical studies, such as cytokine, metabolite and protein analysis. In regression analysis, if an explanatory variable is left-censored due to…

Automated electrocardiogram (ECG) classification is essential for early detection of cardiovascular diseases. While recent approaches have increasingly relied on deep neural networks with complex architectures, we demonstrate that careful…

Machine Learning · Computer Science 2026-03-10 Naqcho Ali Mehdi , Amir Ali

System identification is an exceptionally expansive topic and of remarkable significance in the discipline of signal processing and communication. Our goal in this paper is to show how simple adaptive FIR and IIR filters can be used in…

Signal Processing · Electrical Eng. & Systems 2018-07-19 Ibraheem Kasim Ibraheem

Bayesian statistical inference for Generalized Linear Models (GLMs) with parameters lying on a constrained space is of general interest (e.g., in monotonic or convex regression), but often constructing valid prior distributions supported on…

Methodology · Statistics 2021-09-02 Rahul Ghosal , Sujit K. Ghosh

An essential task in predictive maintenance is the prediction of the Remaining Useful Life (RUL) through the analysis of multivariate time series. Using the sliding window method, Convolutional Neural Network (CNN) and conventional…

Machine Learning · Computer Science 2020-08-11 Yexu Zhou , Yuting Gao , Yiran Huang , Michael Hefenbrock , Till Riedel , Michael Beigl

Computer vision is hard because of a large variability in lighting, shape, and texture; in addition the image signal is non-additive due to occlusion. Generative models promised to account for this variability by accurately modelling the…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Varun Jampani , Sebastian Nowozin , Matthew Loper , Peter V. Gehler

Single-cell RNA sequencing (scRNA-seq) technology provides high-throughput gene expression data to study the cellular heterogeneity and dynamics of complex organisms. Graph neural networks (GNNs) have been widely used for automatic cell…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Chenglin Li , Junni Zou , Dapeng Wu , Hongkai Xiong

In the setting of entangled single-sample distributions, the goal is to estimate some common parameter shared by a family of distributions, given one \emph{single} sample from each distribution. We study mean estimation and linear…

Machine Learning · Computer Science 2020-07-08 Hui Yuan , Yingyu Liang

Genetic variants (GVs) are defined as differences in the DNA sequences among individuals and play a crucial role in diagnosing and treating genetic diseases. The rapid decrease in next generation sequencing cost has led to an exponential…

Machine Learning · Computer Science 2024-12-06 Zehui Li , Vallijah Subasri , Guy-Bart Stan , Yiren Zhao , Bo Wang

Anomaly detection on time series data is increasingly common across various industrial domains that monitor metrics in order to prevent potential accidents and economic losses. However, a scarcity of labeled data and ambiguous definitions…

Machine Learning · Computer Science 2022-12-29 Lawrence Wong , Dongyu Liu , Laure Berti-Equille , Sarah Alnegheimish , Kalyan Veeramachaneni

Single-cell RNA sequencing allows the quantification of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction is a common preprocessing step…

Computation · Statistics 2025-10-14 Cristian Castiglione , Alexandre Segers , Lieven Clement , Davide Risso

Feature extraction is crucial in intelligent fault diagnosis of rotating machinery. It is easier for convolutional neural networks(CNNs) to visually recognize and learn fault features by converting the complicated one-dimensional (1D)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Linshan Jia

Biclustering has gained interest in gene expression data analysis due to its ability to identify groups of samples that exhibit similar behaviour in specific subsets of genes (or vice versa), in contrast to traditional clustering methods…

Applications · Statistics 2024-12-12 Luis A. Vargas-Mieles , Paul D. W. Kirk , Chris Wallace
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