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Electronic health records (EHRs) linked with familial relationship data offer a unique opportunity to investigate the genetic architecture of complex phenotypes at scale. However, existing heritability and coheritability estimation methods…

Methodology · Statistics 2025-11-12 Yinjun Zhao , Nicholas Tatonetti , Yuanjia Wang

The rotation-mass-age relationship offers a promising avenue for measuring the ages of field stars, assuming the attendant uncertainties to this technique can be well characterized. We model stellar angular momentum evolution starting with…

Solar and Stellar Astrophysics · Physics 2013-12-31 Courtney R. Epstein , Marc H. Pinsonneault

Selection analyses of long-term field data frequently use annual comparisons from longlived species with overlapping generations to measure fitness differences with respect to phenotypic characteristics, such as annual phenological timing.…

Populations and Evolution · Quantitative Biology 2025-07-08 F. Stephen Dobson , Claire Saraux , David W. Coltman , Shirley Raveh , Vincent A. Viblanc

Birth weight serves as a fundamental indicator of neonatal health, closely linked to both early medical interventions and long-term developmental risks. Traditional predictive models, often constrained by limited feature selection and…

It is frequently of interest to jointly analyze two paired sequences of multiple tests. This paper studies the problem of detecting whether there are more pairs of tests that are significant in both sequences than would be expected by…

Methodology · Statistics 2017-06-26 Sihai Dave Zhao , T. Tony Cai , Hongzhe Li

Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a single chemical exposure observed at high temporal resolution.…

Objective: To study the longitudinal associations between inattention/hyperactivity symptoms and night-waking in preschool-years, in light of their joint evolution.Study design: Within the French birth-cohort study EDEN, repeated measures…

Applications · Statistics 2019-04-11 Eve Reynaud , Anne Forhan , Barbara Heude , Marie-Aline Charles , Sabine Plancoulaine

Parental origin effects play an important role in mammal development and disorder. Case-control mother-child pair genotype data can be used to detect parental origin effects and is often convenient to collect in practice. Most existing…

Methodology · Statistics 2022-08-11 Yuang Tian , Hong Zhang , Alexandre Bureau , Hagit Hochner , Jinbo Chen

We examine the distribution of heterozygous sites in nine European and nine Yoruban individuals whose genomic sequences were made publicly available by Complete Genomics. We show that it is possible to obtain detailed information about…

Populations and Evolution · Quantitative Biology 2012-12-14 Joshua G. Schraiber , Stephannie Shih , Montgomery Slatkin

The parent-offspring conflict theory is an interesting premise for understanding the dynamics of parental care. However, this theory is not easy to test empirically, as exact measures of parental investment in an experimental set-up are…

Other Quantitative Biology · Quantitative Biology 2018-05-24 Sreejani Sen Majumder , Manabi Paul , Anindita Bhadra

We present a theoretical investigation of the electronic specific heat (ESH) at constant volume (Cv) of single-helical proteins modeled within the tight-binding (TB) framework. We study the effects of helical symmetry, long-range hopping,…

Mesoscale and Nanoscale Physics · Physics 2024-05-22 Sourav Kundu , Siddhartha Lal

Machine learning inference should be subject to stringent inference time constraints while ensuring high inference quality, especially in safety-critical (e.g., autonomous driving) and mission-critical (e.g., emotion recognition) contexts.…

Machine Learning · Computer Science 2024-02-27 Zhengxin Yang , Wanling Gao , Chunjie Luo , Lei Wang , Fei Tang , Xu Wen , Jianfeng Zhan

Pretraining is the preliminary and fundamental step in developing capable language models (LM). Despite this, pretraining data design is critically under-documented and often guided by empirically unsupported intuitions. To address this, we…

Aging experiments of a novel type of large area MCP-PMT made by JUNO collaboration were conducted.In these aging experiments, the multi-photoelectron spectrum and single photoelectron spectrum were measured daily,as well as the MCP…

The study of exoplanets at different evolutionary stages can shed light on their formation, migration, and evolution. The determination of exoplanet properties depends on the properties of their host stars. It is therefore important to…

Do GANs replicate training images? Previous studies have shown that GANs do not seem to replicate training data without significant change in the training procedure. This leads to a series of research on the exact condition needed for GANs…

Machine Learning · Computer Science 2022-02-25 Qianli Feng , Chenqi Guo , Fabian Benitez-Quiroz , Aleix Martinez

We present optical spectra of 45 intermediate mass Herbig Ae/Be stars. Together with the multi-epoch spectroscopic and photometric data compiled for a large sample of these stars and ages estimated for individual stars by using pre-main…

Astrophysics · Physics 2008-11-26 P. Manoj , H. C. Bhatt , G. Maheswar , S. Muneer

Western honeybees (Apis Mellifera) serve extremely important roles in our ecosystem and economics as they are responsible for pollinating $ 215 billion dollars annually over the world. Unfortunately, honeybee population and their colonies…

Populations and Evolution · Quantitative Biology 2020-03-24 Jun Chen , Komi Messan , Marisabel Rodriguez Messan , Gloria DeGrandi-Hoffman , Dingyong Bai , Yun Kang

The honey bees play a role of unquestioned relevance in nature and the comprehension of the mechanisms affecting their population dynamic is of fundamental importance. As experimentally documented, the proper development of a colony is…

Populations and Evolution · Quantitative Biology 2017-09-01 Gianluca Gabbriellini

Many areas of agriculture rely on honey bees to provide pollination services and any decline in honey bee numbers can impact on global food security. In order to understand the dynamics of honey bee colonies we present a discrete time…

Statistics Theory · Mathematics 2016-04-04 Aihua Xia , Richard M. Huggins , Martine J. Barons , Louis Guillot