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In the last decade, an increasing number of users have started reporting Adverse Drug Events (ADE) on social media platforms, blogs, and health forums. Given the large volume of reports, pharmacovigilance has focused on ways to use Natural…

Computation and Language · Computer Science 2022-09-08 Simone Scaboro , Beatrice Portelli , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

Deep learning-based drug response prediction (DRP) methods can accelerate the drug discovery process and reduce R\&D costs. Although the mainstream methods achieve high accuracy in predicting response regression values, the regression-aware…

Biomolecules · Quantitative Biology 2023-12-19 Kun Li , Wenbin Hu

Adverse Event (ADE) extraction is one of the core tasks in digital pharmacovigilance, especially when applied to informal texts. This task has been addressed by the Natural Language Processing community using large pre-trained language…

Computation and Language · Computer Science 2023-06-09 Simone Scaboro , Beatrice Portellia , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

In this paper, we focus on the classification of tweets as sources of potential signals for adverse drug effects (ADEs) or drug reactions (ADRs). Following the intuition that text and drug structure representations are complementary, we…

Quantitative Methods · Quantitative Biology 2023-11-21 Andrey Sakhovskiy , Elena Tutubalina

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Revealing Adverse Drug Reactions (ADR) is an essential part of post-marketing drug surveillance, and data from health-related forums and medical communities can be of a great significance for estimating such effects. In this paper, we…

Information Retrieval · Computer Science 2017-06-20 Liliya Akhtyamova , Andrey Ignatov , John Cardiff

In this study, we establish a benchmark for adverse drug event (ADE) detection in Dutch clinical free-text documents using several transformer models, clinical scenarios, and fit-for-purpose performance measures. We trained a Bidirectional…

Spontaneous reporting system databases are key resources for post-marketing surveillance, providing real-world evidence (RWE) on the adverse events (AEs) of regulated drugs or other medical products. Various statistical methods have been…

Methodology · Statistics 2026-03-24 Xin-Wei Huang , Saptarshi Chakraborty

Automatic Speech Recognition (ASR) technology is fundamental in transcribing spoken language into text, with considerable applications in the clinical realm, including streamlining medical transcription and integrating with Electronic…

Computation and Language · Computer Science 2024-03-27 Nima Ebadi , Kellen Morgan , Adrian Tan , Billy Linares , Sheri Osborn , Emma Majors , Jeremy Davis , Anthony Rios

In this work, we present the first corpus for German Adverse Drug Reaction (ADR) detection in patient-generated content. The data consists of 4,169 binary annotated documents from a German patient forum, where users talk about health issues…

Computation and Language · Computer Science 2022-08-04 Lisa Raithel , Philippe Thomas , Roland Roller , Oliver Sapina , Sebastian Möller , Pierre Zweigenbaum

Pharmacovigilance is the field of science devoted to the collection, analysis and prevention of Adverse Drug Reactions (ADRs). Efficient strategies for the extraction of information about ADRs from free text resources are essential to…

Computation and Language · Computer Science 2017-01-18 Carlo Combi , Riccardo Lora , Ugo Moretti , Marco Pagliarini , Margherita Zorzi

Adverse drug reaction (ADR) is widely concerned for public health issue. ADRs are one of most common causes to withdraw some drugs from market. Prescription event monitoring (PEM) is an important approach to detect the adverse drug…

Computational Engineering, Finance, and Science · Computer Science 2013-07-08 Yihui Liu , Uwe Aickelin

Adverse drug reactions (ADRs) are a major barrier to safe and effective pharmacotherapy and increasingly reflect higher order interactions between drugs, genetic background, and clinical phenotypes. Existing graph based approaches usually…

Quantitative Methods · Quantitative Biology 2025-12-02 Ze Cai , Haotian Tang , Shuai Gao , Binbin Zhou , Junhan Zhao , Jun Wen

Anomaly detection (AD) is an important machine learning task with applications in fraud detection, content moderation, and user behavior analysis. However, AD is relatively understudied in a natural language processing (NLP) context,…

Computation and Language · Computer Science 2025-10-13 Yuangang Li , Jiaqi Li , Zhuo Xiao , Tiankai Yang , Yi Nian , Xiyang Hu , Yue Zhao

This paper presents our approach for task 2 and task 3 of Social Media Mining for Health (SMM4H) 2020 shared tasks. In task 2, we have to differentiate adverse drug reaction (ADR) tweets from nonADR tweets and is treated as binary…

Computation and Language · Computer Science 2020-06-30 Katikapalli Subramanyam Kalyan , S. Sangeetha

Population-scale drug prescription data linked with adverse drug reaction (ADR) data supports the fitting of models large enough to detect drug use and ADR patterns that are not detectable using traditional methods on smaller datasets.…

Quantitative Methods · Quantitative Biology 2021-06-02 Tengel Ekrem Skar , Einar Holsbø , Kristian Svendsen , Lars Ailo Bongo

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and…

The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Adverse Events (AE) are harmful events resulting from the use of medical products. Although social media may be crucial for early AE detection, the sheer scale of this data makes it logistically intractable to analyze using human agents,…

Computation and Language · Computer Science 2021-09-14 Shivam Raval , Hooman Sedghamiz , Enrico Santus , Tuka Alhanai , Mohammad Ghassemi , Emmanuele Chersoni