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We consider outbreak detection settings of endemic diseases where the population under study consists of various subpopulations available for stratified surveillance. These subpopulations can for example be based on age cohorts, but may…

Methodology · Statistics 2026-05-11 Ivo V. Stoepker

Pooled and individual disease testing are common methods for determining the population prevalences of diseases. Recently, researchers have used Monte Carlo Markov Chain methods to estimate population prevalence from the combined streams of…

Methodology · Statistics 2023-08-23 Matthew Ritch , Charles Copley

This paper presents methods to choose individuals to test for infection during a pandemic such as COVID-19, characterized by high contagion and presence of asymptomatic carriers. The smart-testing ideas presented here are motivated by…

Machine Learning · Computer Science 2020-12-29 Yingfei Wang , Inbal Yahav , Balaji Padmanabhan

The COVID-19 pandemic has impacted lives and economies across the globe, leading to many deaths. While vaccination is an important intervention, its roll-out is slow and unequal across the globe. Therefore, extensive testing still remains…

Network sampling is used around the world for surveys of vulnerable, hard-to-reach populations including people at risk for HIV, opioid misuse, and emerging epidemics. The sampling methods include tracing social links to add new people to…

Methodology · Statistics 2020-02-05 Steve Thompson

Coronavirus outbreak is one of the most challenging pandemics for the entire human population of the planet Earth. Techniques such as the isolation of infected persons and maintaining social distancing are the only preventive measures…

Social and Information Networks · Computer Science 2020-09-01 Rahul Mishra , Hari Prabhat Gupta , Tanima Dutta

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the…

Methodology · Statistics 2023-04-19 Patrick M. Schnell , Matthew Wascher , Grzegorz A. Rempala

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

Applications · Statistics 2021-07-21 Matthew Aldridge

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

Causal inference is crucial for understanding the true impact of interventions, policies, or actions, enabling informed decision-making and providing insights into the underlying mechanisms that shape our world. In this paper, we establish…

Methodology · Statistics 2024-03-26 Jingyue Huang , Changbao Wu , Leilei Zeng

The epidemiology of pandemics is classically viewed using geographical and political borders; however, these artificial divisions can result in a misunderstanding of the current epidemiological state within a given region. To improve upon…

Populations and Evolution · Quantitative Biology 2023-11-28 David Lyver , Mihai Nica , Corentin Cot , Giacomo Cacciapaglia , Zahra Mohammadi , Edward W. Thommes , Monica-Gabriela Cojocaru

Breaking a complex bio-social phenomenon (epidemic) into its components, considering the processes that determine its dynamics, formalizing the accepted hypotheses in mathematical equations, selecting appropriate experimental and…

Physics and Society · Physics 2020-06-16 A. V. Sokolov , L. A. Sokolova

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

Methodology · Statistics 2020-08-26 Arjun Kodialam

Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never…

Machine Learning · Computer Science 2021-10-20 Sarwan Ali , Yijing Zhou , Murray Patterson

It is crucial for policymakers to understand the community prevalence of COVID-19 so combative resources can be effectively allocated and prioritized during the COVID-19 pandemic. Traditionally, community prevalence has been assessed…

Rapid testing of appropriate specimens from patients suspected for a disease during an epidemic, such as the current Coronavirus outbreak, is of a great importance for the disease management and control. We propose a method to enhance…

Quantitative Methods · Quantitative Biology 2020-04-27 Usama Kadri

Currently, novel coronavirus disease 2019 (COVID-19) is a big threat to global health. The rapid spread of the virus has created pandemic, and countries all over the world are struggling with a surge in COVID-19 infected cases. There are no…

Applications · Statistics 2020-09-08 Se Yoon Lee , Bowen Lei , Bani K. Mallick

When pandemics like COVID-19 spread around the world, the rapidly evolving situation compels officials and executives to take prompt decisions and adapt policies depending on the current state of the disease. In this context, it is crucial…

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

Physics and Society · Physics 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone