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A common scenario in a variety of biological systems is that multiple particles are searching in parallel for an immobile target located in a bounded domain, and the fastest among them that arrives to the target first triggers a given…

Statistical Mechanics · Physics 2025-07-15 Denis S. Grebenkov , Ralf Metzler , Gleb Oshanin

We study the statistics of the first-passage time of a single run and tumble particle (RTP) in one spatial dimension, with or without resetting, to a fixed target located at $L>0$. First, we compute the first-passage time distribution of a…

Statistical Mechanics · Physics 2023-03-20 Gennaro Tucci , Andrea Gambassi , Satya N. Majumdar , Gregory Schehr

It is shown that the kinetics of time-reversible chemical reactions having the same equilibrium constant but different initial conditions are closely related to one another by a directly measurable symmetry relation analogous to chemical…

Statistical Mechanics · Physics 2009-11-11 Artur B. Adib

One-dimensional reaction-diffusion systems are mapped through a similarity transformation onto integrable (and a priori non-stochastic) quantum chains. Time-dependent properties of these chemical models can then be found exactly. The…

Statistical Mechanics · Physics 2009-10-28 Malte Henkel , Enzo Orlandini , Jaime Santos

Basic theoretical issues relating to the response of confined relativistic particles are considered including the scaling of the response in spacelike and timelike regions of momentum transfer and the role of final state interactions. A…

Nuclear Theory · Physics 2009-11-07 Mark W. Paris

The reversible reactions A+A<=>C and A+B<=>C are investigated. From the exact Langevin equations describing our model, we set up a systematic approximation scheme to compute the approach of the density of C particles to its equilibrium…

Statistical Mechanics · Physics 2009-10-31 Pierre-Antoine Rey , John Cardy

Mechanical responses of soft particle packings to quasi-static deformations are determined by the microscopic restructuring of force-chain networks, where complex non-affine displacements of constituent particles cause the irreversible…

Soft Condensed Matter · Physics 2015-07-17 Kuniyasu Saitoh , Vanessa Magnanimo , Stefan Luding

In this paper we consider a threshold surface absorption mechanism for a particle diffusing in a domain containing a single target $\calU $. The target boundary $\partial \calU$ is taken to be a reactive surface that modifies an internal…

Statistical Mechanics · Physics 2022-04-12 Paul C. Bressloff

The problem of the time required for a diffusing molecule, within a large bounded domain, to first locate a small target is prevalent in biological modeling. Here we study this problem for a small spherical target. We develop uniform in…

Biological Physics · Physics 2013-08-06 Samuel A. Isaacson , Jay Newby

We investigate the dynamics of a quantum system subjected to a time-dependent and conditional resetting protocol. Namely, we ask: what happens when the unitary evolution of the system is repeatedly interrupted at random time instants with…

Statistical Mechanics · Physics 2023-12-20 Anish Acharya , Shamik Gupta

Diffusion with an incorporated resetting mechanism provides a reference framework for modeling a wide range of natural phenomena. Within this framework, the optimal resetting rate is a key quantity that arises from the optimization of the…

Statistical Mechanics · Physics 2026-05-12 Pedro Julián-Salgado , Pavel Castro-Villarreal , Leonardo Dagdug , Denis Boyer

We investigate theoretically the effect of polymer tension on the collective behavior of reversibly binding cross-links. For this purpose, we employ a model of two weakly bending wormlike chains aligned in parallel by a tensile force, with…

Biological Physics · Physics 2015-02-10 Panayotis Benetatos , Alice von der Heydt , Annette Zippelius

Motivated by the study of reversal behaviour of myxobacteria, in this article we are interested in a kinetic model for reversal dynamics, in which particles with directions close to be opposite undergo binary collision resulting in…

Analysis of PDEs · Mathematics 2023-05-22 Amic Frouvelle , Laura Kanzler , Christian Schmeiser

The effect of partial absorption on a diffusive particle which stochastically resets its position with a finite rate $r$ is considered. The particle is absorbed by a target at the origin with absorption `velocity' $a$; as the velocity $a$…

Statistical Mechanics · Physics 2015-06-12 Justin Whitehouse , Martin R. Evans , Satya N. Majumdar

Assembly of protein complexes like virus shells, the centriole, the nuclear pore complex or the actin cytoskeleton is strongly determined by their spatial structure. Moreover it is becoming increasingly clear that the reversible nature of…

Subcellular Processes · Quantitative Biology 2014-05-13 Heinrich C. R. Klein , Ulrich S. Schwarz

We revisit the problem of pinning a reaction-diffusion front by a defect, in particular by a reaction-free region. Using collective variables for the front and numerical simulations, we compare the behaviors of a bistable and monostable…

Pattern Formation and Solitons · Physics 2021-03-31 Jean-Guy Caputo , Gustavo Cruz-Pacheco , Benoit Sarels

This paper is concerned with the dynamical properties of deterministically modeled chemical reaction systems with mass-action kinetics. Such models are ubiquitously found in chemistry, population biology, and the burgeoning field of systems…

Dynamical Systems · Mathematics 2011-06-20 David F. Anderson

Nanoparticles with multiple ligands have been proposed for use in nanomedicine. The multiple targeting ligands on each nanoparticle can bind to several locations on a cell surface facilitating both drug targeting and uptake. Experiments…

Mesoscale and Nanoscale Physics · Physics 2015-05-18 Jack N. Waddell , Douglas G. Mullen , Bradford G. Orr , Mark M. Banaszak Holl , Leonard M. Sander

Reaction-diffusion equations are studied on bounded, time-periodic domains with zero Dirichlet boundary conditions. The long-time behaviour is shown to depend on the principal periodic eigenvalue of a transformed periodic-parabolic problem.…

Analysis of PDEs · Mathematics 2023-07-18 Jane Allwright

We present a unified approach to those observables of stochastic processes under reset that take the form of averages of functionals depending on the most recent renewal period. We derive solutions for the observables, and determine the…

Soft Condensed Matter · Physics 2019-03-28 G. John Lapeyre , Marco Dentz