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This study presents a multimodal machine learning model to predict ICD-10 diagnostic codes. We developed separate machine learning models that can handle data from different modalities, including unstructured text, semi-structured text and…

In the past decade a surge in the amount of electronic health record (EHR) data in the United States, attributed to a favorable policy environment created by the Health Information Technology for Economic and Clinical Health (HITECH) Act of…

Computation and Language · Computer Science 2025-12-08 Ivan Makohon , Mohamad Najafi , Jian Wu , Mathias Brochhausen , Yaohang Li

Medical coding is essential for standardizing clinical data and communication but is often time-consuming and prone to errors. Traditional Natural Language Processing (NLP) methods struggle with automating coding due to the large label…

Automated international classification of diseases (ICD) coding aims to assign multiple disease codes to clinical documents and plays a critical role in healthcare informatics. However, its performance is hindered by the extreme long-tail…

Machine Learning · Computer Science 2026-01-13 Tianlei Chen , Yuxiao Chen , Yang Li , Feifei Wang

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Clinical coding is currently a labour-intensive, error-prone, but critical administrative process whereby hospital patient episodes are manually assigned codes by qualified staff from large, standardised taxonomic hierarchies of codes.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard JB Dobson

Automatic International Classification of Diseases (ICD) coding is defined as a kind of text multi-label classification problem, which is difficult because the number of labels is very large and the distribution of labels is unbalanced. The…

Computation and Language · Computer Science 2021-06-21 Yifan Wu , Min Zeng , Ying Yu , Min Li

Although the International Classification of Diseases (ICD) has been adopted worldwide, manually assigning ICD codes to clinical text is time-consuming, error-prone, and expensive, motivating the development of automated approaches. This…

Computation and Language · Computer Science 2024-02-06 Gonçalo Gomes , Isabel Coutinho , Bruno Martins

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

The translation of medical diagnosis to clinical coding has wide range of applications in billing, aetiology analysis, and auditing. Currently, coding is a manual effort while the automation of such task is not straight forward. Among the…

Clinical notes, which can be embedded into electronic medical records, document patient care delivery and summarize interactions between healthcare providers and patients. These clinical notes directly inform patient care and can also…

Computation and Language · Computer Science 2022-03-25 Suzanna Schmeelk , Martins Samuel Dogo , Yifan Peng , Braja Gopal Patra

Clinicians may rely on medical coding systems such as International Classification of Diseases (ICD) to identify patients with diseases from Electronic Health Records (EHRs). However, due to the lack of detail and specificity as well as a…

Computation and Language · Computer Science 2022-05-19 Jingqing Zhang , Atri Sharma , Luis Bolanos , Tong Li , Ashwani Tanwar , Vibhor Gupta , Yike Guo

Automated International Classification of Diseases (ICD) coding assigns standardized diagnosis and procedure codes to clinical records, playing a critical role in healthcare systems. However, existing methods face challenges such as…

Computation and Language · Computer Science 2025-11-12 Mucheng Ren , He Chen , Yuchen Yan , Danqing Hu , Jun Xu , Xian Zeng

Prediction of medical codes from clinical notes is both a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort spent by…

Computation and Language · Computer Science 2021-07-23 Byung-Hak Kim , Varun Ganapathi

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu

Problem lists are intended to provide clinicians with a relevant summary of patient medical issues and are embedded in many electronic health record systems. Despite their importance, problem lists are often cluttered with resolved or…

Information Retrieval · Computer Science 2020-08-05 Justin Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

The disease coding task involves assigning a unique identifier from a controlled vocabulary to each disease mentioned in a clinical document. This task is relevant since it allows information extraction from unstructured data to perform,…

Computation and Language · Computer Science 2024-07-29 Fabián Villena , Matías Rojas , Felipe Arias , Jorge Pacheco , Paulina Vera , Jocelyn Dunstan

Medical coding is a complex task, requiring assignment of a subset of over 72,000 ICD codes to a patient's notes. Modern natural language processing approaches to these tasks have been challenged by the length of the input and size of the…

Machine Learning · Computer Science 2022-08-17 Jay DeYoung , Han-Chin Shing , Luyang Kong , Christopher Winestock , Chaitanya Shivade