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Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

Tunnel lining crack is a crucial indicator of tunnels' safety status. Aiming to classify and segment tunnel cracks with enhanced accuracy and efficiency, this study proposes a two-step deep learning-based method. An automatic tunnel image…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Yong Feng , Xiaolei Zhang , Shijin Feng , Yong Zhao , Yihan Chen

This paper uses the peridynamic theory, which is well-suited to crack studies, to predict the crack patterns in a moving disk and classify them according to the modes and finally perform regression analysis. In that way, the crack patterns…

Computational Engineering, Finance, and Science · Computer Science 2020-05-28 Moonseop Kim , Guang Lin

Flexible road pavements deteriorate primarily due to traffic and adverse environmental conditions. Cracking is the most common deterioration mechanism; the surveying thereof is typically conducted manually using internationally defined…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Hermann Tapamo , Anna Bosman , James Maina , Emile Horak

Many biochemical systems appearing in applications have a multiscale structure so that they converge to piecewise deterministic Markov processes in a thermodynamic limit. The statistics of the piecewise deterministic process can be obtained…

Computational Physics · Physics 2016-12-30 Ethan Levien , Paul C. Bressloff

The estimation of regression parameters in one dimensional broken stick models is a research area of statistics with an extensive literature. We are interested in extending such models by aiming to recover two or more intersecting…

Methodology · Statistics 2025-03-11 Georg Hahn , Moulinath Banerjee , Bodhisattva Sen

The accurate and efficient prediction of crack propagation in dielectric materials is a critical challenge in structural health monitoring and the design of smart systems. This work presents a hybrid modeling framework that combines an…

Computational Physics · Physics 2026-02-03 Aamir Dean , Jaykumar Mavani , Betim Bahtiri , Behrouz Arash , Raimund Rolfes

Estimation of Markov Random Field and covariance models from high-dimensional data represents a canonical problem that has received a lot of attention in the literature. A key assumption, widely employed, is that of {\em sparsity} of the…

Optimization and Control · Mathematics 2018-05-16 Davoud Ataee Tarzanagh , George Michailidis

Fracture is one of the main failure modes of engineering structures such as buildings and roads. Effective detection of surface cracks is significant for damage evaluation and structure maintenance. In recent years, the emergence and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Yu Zhang , Lin Zhang

Stochastic kernel based dimensionality reduction approaches have become popular in the last decade. The central component of many of these methods is a symmetric kernel that quantifies the vicinity between pairs of data points and a…

Machine Learning · Computer Science 2018-08-08 Purushottam D. Dixit

A robust $hp$-adaptive finite element framework is presented for the investigation of static cracks in materials characterized by complex, pointwise density variations. Within such heterogeneous media, the equilibrium equation governed by…

Numerical Analysis · Mathematics 2025-12-29 S. M. Mallikarjunaiah

The equivalent permeability of a randomly cracked porous material is studied using a finite element program in which a four-nodes zero-thickness element is implemented for modelling the cracks. The numerical simulations are performed for…

Classical Physics · Physics 2008-10-07 Siavash Ghabezloo , Ahmad Pouya

Molecular property calculations are the bedrock of chemical physics. High-fidelity \textit{ab initio} modeling techniques for computing the molecular properties can be prohibitively expensive, and motivate the development of…

Machine Learning · Computer Science 2022-11-28 Hatem Helal , Jesun Firoz , Jenna Bilbrey , Mario Michael Krell , Tom Murray , Ang Li , Sotiris Xantheas , Sutanay Choudhury

Markov Chain Monte Carlo (MCMC) method is a widely used algorithm design scheme with many applications. To make efficient use of this method, the key step is to prove that the Markov chain is rapid mixing. Canonical paths is one of the two…

Data Structures and Algorithms · Computer Science 2015-10-15 Lingxiao Huang , Pinyan Lu , Chihao Zhang

A physics-informed machine learning framework based on holomorphic neural networks is introduced for detecting cracks in two-dimensional solids from strain or displacement data. Crack detection is formulated as an inverse problem in which…

Computational Engineering, Finance, and Science · Computer Science 2026-03-16 Jonas Hund , Nicolas Cuenca , Tito Andriollo

Crack detection has become an indispensable, interesting yet challenging task in the computer vision community. Specially, pavement cracks have a highly complex spatial structure, a low contrasting background and a weak spatial continuity,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-22 Junbiao Pang , Baocheng Xiong , Jiaqi Wu

The use of machine learning algorithms is an attractive way to produce very fast detector simulations for scattering reactions that can otherwise be computationally expensive. Here we develop a factorised approach where we deal with each…

Data Analysis, Statistics and Probability · Physics 2022-07-26 D. Darulis , R. Tyson , D. G. Ireland , D. I. Glazier , B. McKinnon , P. Pauli

Modeling fracture is computationally expensive even in computational simulations of two-dimensional problems. Hence, scaling up the available approaches to be directly applied to large components or systems crucial for real applications…

Computational Engineering, Finance, and Science · Computer Science 2022-07-07 Ayan Chakraborty , Cosmin Anitescu , Somdatta Goswami , Xiaoying Zhuang , Timon Rabczuk

The design of reliable indicators to anticipate critical transitions in complex systems is an im portant task in order to detect a coming sudden regime shift and to take action in order to either prevent it or mitigate its consequences. We…

Data Analysis, Statistics and Probability · Physics 2022-12-14 Martin Heßler , Oliver Kamps

Effective thermal conductivity is an important property of composites for different thermal management applications. Although physics-based methods, such as effective medium theory and solving partial differential equation, dominate the…

Computational Physics · Physics 2019-04-15 Qingyuan Rong , Han Wei , Hua Bao