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The increasing use of Machine Learning (ML) in sensitive domains such as healthcare, finance, and public policy has raised concerns about the transparency of automated decisions. Explainable AI (XAI) addresses this by clarifying how models…

Artificial Intelligence · Computer Science 2026-02-13 Natalia Abarca , Andrés Carvallo , Claudia López Moncada , Felipe Bravo-Marquez

The explanation to an AI model's prediction used to support decision making in cyber security, is of critical importance. It is especially so when the model's incorrect prediction can lead to severe damages or even losses to lives and…

Cryptography and Security · Computer Science 2022-11-21 Zhi Lu , Vrizlynn L. L. Thing

A main drawback of eXplainable Artificial Intelligence (XAI) approaches is the feature independence assumption, hindering the study of potential variable dependencies. This leads to approximating black box behaviors by analyzing the effects…

Artificial Intelligence · Computer Science 2024-10-16 Martina Cinquini , Riccardo Guidotti

Melanoma is one of the most aggressive and deadliest skin cancers, leading to mortality if not detected and treated in the early stages. Artificial intelligence techniques have recently been developed to help dermatologists in the early…

Machine Learning · Computer Science 2026-02-19 Wadduwage Shanika Perera , ABM Islam , Van Vung Pham , Min Kyung An

Explainable Artificial Intelligence (XAI) aims to improve the transparency of machine learning (ML) pipelines. We systematize the increasingly growing (but fragmented) microcosm of studies that develop and utilize XAI methods for defensive…

Cryptography and Security · Computer Science 2023-03-06 Azqa Nadeem , Daniël Vos , Clinton Cao , Luca Pajola , Simon Dieck , Robert Baumgartner , Sicco Verwer

A high-velocity paradigm shift towards Explainable Artificial Intelligence (XAI) has emerged in recent years. Highly complex Machine Learning (ML) models have flourished in many tasks of intelligence, and the questions have started to shift…

Machine Learning · Computer Science 2024-05-31 Jacob Dineen , Don Kridel , Daniel Dolk , David Castillo

Recent advances in machine learning have led to growing interest in Explainable AI (xAI) to enable humans to gain insight into the decision-making of machine learning models. Despite this recent interest, the utility of xAI techniques has…

Artificial Intelligence · Computer Science 2022-09-09 Rohan Paleja , Muyleng Ghuy , Nadun Ranawaka Arachchige , Reed Jensen , Matthew Gombolay

In recent years, deep learning has achieved unprecedented success in various computer vision tasks, particularly in object detection. However, the black-box nature and high complexity of deep neural networks pose significant challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 FatemehSadat Seyedmomeni , Mohammad Ali Keyvanrad

Due to the sensitive nature of medicine, it is particularly important and highly demanded that AI methods are explainable. This need has been recognised and there is great research interest in xAI solutions with medical applications.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Luisa Gallée , Catharina Silvia Lisson , Christoph Gerhard Lisson , Daniela Drees , Felix Weig , Daniel Vogele , Meinrad Beer , Michael Götz

Explainable AI (XAI) is a necessity in safety-critical systems such as in clinical diagnostics due to a high risk for fatal decisions. Currently, however, XAI resembles a loose collection of methods rather than a well-defined process. In…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Lukas Klein , Mennatallah El-Assady , Paul F. Jäger

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

Existing artificial intelligence (AI) models for diagnosing knee osteoarthritis (OA) have faced criticism for their lack of transparency and interpretability, despite achieving medical-expert-like performance. This opacity makes them…

Machine Learning · Computer Science 2023-08-21 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand-supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Tin Lai

Artificial Intelligence (AI) is rapidly expanding and integrating more into daily life to automate tasks, guide decision making, and enhance efficiency. However, complex AI models, which make decisions without providing clear explanations…

Software Engineering · Computer Science 2025-09-03 Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj , Dipen Pradhan , Ankit Shetgaonkar

We share observations and challenges from an ongoing effort to implement Explainable AI (XAI) in a domain-specific workflow for cybersecurity analysts. Specifically, we briefly describe a preliminary case study on the use of XAI for source…

Human-Computer Interaction · Computer Science 2024-08-12 Ashley Suh , Harry Li , Caitlin Kenney , Kenneth Alperin , Steven R. Gomez

The remarkable advancements in Deep Learning (DL) algorithms have fueled enthusiasm for using Artificial Intelligence (AI) technologies in almost every domain; however, the opaqueness of these algorithms put a question mark on their…

Machine Learning · Computer Science 2021-01-12 F. Hussain , R. Hussain , E. Hossain

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

EXplainable Artificial Intelligence (XAI) aims to help users to grasp the reasoning behind the predictions of an Artificial Intelligence (AI) system. Many XAI approaches have emerged in recent years. Consequently, a subfield related to the…

Herein, we present the application of MEGAN, our explainable AI (xAI) model, for the identification of small colloidally aggregating molecules (SCAMs). This work offers solutions to the long-standing problem of false positives caused by…

Biomolecules · Quantitative Biology 2025-05-28 Hunter Sturm , Jonas Teufel , Kaitlin A. Isfeld , Pascal Friederich , Rebecca L. Davis

The novel 2019 Coronavirus disease (COVID-19) global pandemic is a defining health crisis. Recent efforts have been increasingly directed towards achieving quick and accurate detection of COVID-19 across symptomatic patients to mitigate the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Karina Yang , Alexis Bennett , Dominique Duncan