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Poly-PL kinetic systems are kinetic systems consisting of nonnegative linear combinations of power law functions. In this contribution, we analyze these kinetic systems using two main approaches: (1) we define a canonical power law…

Dynamical Systems · Mathematics 2021-07-13 Noel T. Fortun , Dylan Antonio SJ. Talabis , Editha C. Jose , Eduardo R. Mendoza

This work introduces a novel approach to study properties of positive equilibria of a chemical reaction network $\mathscr{N}$ endowed with Hill-type kinetics $K$, called a Hill-type kinetic (HTK) system $\left(\mathscr{N},K\right)$,…

Dynamical Systems · Mathematics 2020-09-08 Bryan S. Hernandez , Eduardo R. Mendoza

Very often, models in biology, chemistry, physics, and engineering are systems of polynomial or power-law ordinary differential equations, arising from a reaction network. Such dynamical systems can be generated by many different reaction…

Dynamical Systems · Mathematics 2020-01-01 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

Studies about the set of positive equilibria ($E_+$) of kinetic systems have been focused on mass action, and not that much on power law kinetic (PLK) systems, even for PL-RDK systems (PLK systems where two reactions with identical reactant…

Dynamical Systems · Mathematics 2022-04-06 Bryan S. Hernandez , Eduardo R. Mendoza

One important question that interests those who work in chemical reaction network theory (CRNT) is this: Does the system obtained from a reaction network admit a positive equilibrium and if it does, can there be more than one within a…

There have been recent theoretic results that provide sufficient conditions for the existence of a species displaying absolute concentration robustness (ACR) in a power law kinetic (PLK) system. One such result involves the detection of ACR…

Chemical Physics · Physics 2020-11-06 Lauro L. Fontanil , Eduardo R. Mendoza , Noel T. Fortun

In this paper, we study various theoretical properties of a class of prioritized inverse kinematics (PIK) solutions that can be considered as a class of (output regulation or tracking) control laws of a dynamical system with prioritized…

Systems and Control · Computer Science 2020-01-24 Sang-ik An , Dongheui Lee

Robustness against the presence of environmental disruptions can be observed in many systems of chemical reaction network. However, identifying the underlying components of a system that give rise to robustness is often elusive. The…

Dynamical Systems · Mathematics 2020-03-31 Noel T. Fortun , Angelyn R. Lao , Luis F. Razon , Eduardo R. Mendoza

For a reaction network with species set $\mathscr{S}$, a log-parametrized (LP) set is a non-empty set of the form $E(P, x^*) = \{x \in \mathbb{R}^\mathscr{S}_> \mid \log x - \log x^* \in P^\perp\}$ where $P$ (called the LP set's flux…

Algebraic Geometry · Mathematics 2021-10-27 Angelyn R. Lao , Patrick Vincent N. Lubenia , Daryl M. Magpantay , Eduardo R. Mendoza

Chemical reaction networks with generalized mass-action kinetics lead to power-law dynamical systems. As a simple example, we consider the Lotka reactions with two chemical species and arbitrary power-law kinetics. We study existence,…

Dynamical Systems · Mathematics 2022-09-14 Balázs Boros , Josef Hofbauer , Stefan Müller

We study the global stability of generalized Lotka-Volterra systems with generalized polynomial right-hand side, without restrictions on the number of variables or the polynomial degree, including negative and non-integer degree. We…

Dynamical Systems · Mathematics 2024-12-19 Diego Rojas La Luz , Gheorghe Craciun , Polly Y. Yu

This paper presents a computational solution to determine if a chemical reaction network endowed with power-law kinetics (PLK system) has the capacity for multistationarity, i.e., whether there exist positive rate constants such that the…

Dynamical Systems · Mathematics 2020-02-19 Bryan S. Hernandez , Eduardo R. Mendoza , Aurelio A. de los Reyes

Reversibility, weak reversibility and deficiency, detailed and complex balancing are generally not "encoded" in the kinetic differential equations but they are realization properties that may imply local or even global asymptotic stability…

Molecular Networks · Quantitative Biology 2011-05-11 Gabor Szederkenyi , Katalin M. Hangos

We consider kinetic systems and prove their stability working in weighted spaces in which the systems are symmetric. We prove stability for various explicit and implicit semi-discrete and fully discrete schemes. The applications include…

Numerical Analysis · Mathematics 2017-08-07 F. Patricia Medina , Malgorzata Peszynska

It is well known that, for mass-action systems, complex-balanced equilibria are asymptotically stable. For generalized mass-action systems, even if there exists a unique complex-balanced equilibrium (in every stoichiometric class and for…

Dynamical Systems · Mathematics 2022-09-14 Balazs Boros , Stefan Müller , Georg Regensburger

This paper studies the relations among system parameters, uniqueness, and stability of equilibria, for kinetic systems given in the form of polynomial ODEs. Such models are commonly used to describe the dynamics of nonnegative systems, with…

Molecular Networks · Quantitative Biology 2016-11-14 Antonio A. Alonso , Gabor Szederkenyi

A kinetic system has an absolute concentration robustness (ACR) for a molecular species if its concentration remains the same in every positive steady state of the system. Just recently, a condition that sufficiently guarantees the…

Dynamical Systems · Mathematics 2023-04-10 Eduardo R. Mendoza , Dylan Antonio SJ. Talabis , Editha C. Jose , Lauro L. Fontanil

Understanding the structural evolution of granular systems is a long-standing problem. A recently proposed theory for such dynamics in two dimensions predicts that steady states of very dense systems satisfy detailed-balance. We analyse…

Soft Condensed Matter · Physics 2023-08-16 Alex D. C. Myhill , Raphael Blumenfeld

Generalized mass-action systems are power-law dynamical systems arising from chemical reaction networks. Essentially, every nonnegative ODE model used in chemistry and biology (for example, in ecology and epidemiology) and even in economics…

Dynamical Systems · Mathematics 2023-11-21 Stefan Müller , Georg Regensburger

A class of polynomial dynamical systems called complex-balanced are locally stable and conjectured to be globally stable. In general, complex-balancing is not a robust property, i.e., small changes in parameter values may result in the loss…

Dynamical Systems · Mathematics 2022-10-26 Polly Y. Yu
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