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Quantum phase imaging enables the analysis of transparent samples with thickness and refractive index variations in scenarios requiring precise measurements under low-light conditions. Here, we present a compact quantum phase-gradient…

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

Endoscopes are an important component for the development of minimally invasive surgeries. Their size is one of the most critical aspects, because smaller and less rigid endoscopes enable higher agility, facilitate larger accessibility, and…

Computational imaging modalities support a simplification of the active architectures required in an imaging system and these approaches have been validated across the electromagnetic spectrum. Recent implementations have utilized…

Classical Physics · Physics 2016-08-24 Thomas Fromenteze , Xiaojun Liu , Michael Boyarsky , Jonah Gollub , David R. Smith

Quantitative phase imaging has been extensively studied in X-ray microtomography to improve the sensitivity and specificity of measurements, especially for low atomic number materials. However, obtaining quantitative phase images typically…

Optics · Physics 2026-02-25 KyeoReh Lee , Herve Hugonnet , Jae-Hong Lim , YongKeun Park

With the advent of neuroimaging and microsurgery, there is a rising need for capturing images through an optical fiber. We present an approach of imaging through a single fiber without mechanical scanning by implementing spatial-spectral…

We present geometric-phase microscopy allowing a multipurpose quantitative phase imaging in which the ground-truth phase is restored by quantifying the phase retardance. The method uses broadband spatially incoherent light that is…

The structural complexity and instability of many interference phase microscopy methods are the major obstacles toward high-precision phase measurement. In this vein, improving more efficient configurations as well as proposing new methods…

Optics · Physics 2020-01-08 Samira Ebrahimi , Masoomeh Dashtdar

We suggest a new multimodal imaging technique for quantitatively measuring the integral (thickness-average) refractive index of the nuclei of live biological cells in suspension. For this aim, we combined quantitative phase microscopy with…

Multipartite entanglement tomography, namely the quantum Fisher information (QFI) calculated with respect to different collective operators, allows to fully characterize the phase diagram of the quantum Ising chain in a transverse field…

Quantum Physics · Physics 2019-05-22 Marco Gabbrielli , Luca Lepori , Luca Pezzè

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Wide-field mid-infrared photothermal (MIP) imaging offers rapid labelfree chemical contrast for biomedical and polymer analysis. However, its field of view (FOV) is limited by the pulse intensity of conventional infrared lasers. Here, we…

We study the role of quantum entanglement (particle entanglement and mode entanglement) in optical phase estimation by employing the first and second quantization formalisms of quantum mechanics. The quantum Fisher information (QFI) is…

Quantum Physics · Physics 2016-09-23 Jaspreet Sahota , Nicolás Quesada , Daniel F. V. James

Quantitative phase imaging has become a topic of considerable interest in the microscopy community. We have recently described one such technique based on the use of a partitioned detection aperture, which can be operated in a single shot…

Optics · Physics 2015-10-20 Roman Barankov , Jean-Charles Baritaux , Jerome Mertz

Quantitative magnetic resonance imaging (qMRI) requires multi-phase acqui-sition, often relying on reduced data sampling and reconstruction algorithms to accelerate scans, which inherently poses an ill-posed inverse problem. While many…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Haozhong Sun , Zhongsen Li , Chenlin Du , Haokun Li , Yajie Wang , Huijun Chen

We propose a dictionary-matching-free pipeline for multi-parametric quantitative MRI image computing. Our approach has two stages based on compressed sensing reconstruction and deep learned quantitative inference. The reconstruction phase…

Computer Vision and Pattern Recognition · Computer Science 2020-04-23 Mohammad Golbabaee , Guido Buonincontri , Carolin Pirkl , Marion Menzel , Bjoern Menze , Mike Davies , Pedro Gomez

In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter. This is particularly important in medical imaging applications, such as…

Optimization and Control · Mathematics 2024-04-12 Guozhi Dong , Moritz Flaschel , Michael Hintermüller , Kostas Papafitsoros , Clemens Sirotenko , Karsten Tabelow

Tissue biopsy evaluation in the clinic is in need of quantitative disease markers for diagnosis and, most importantly, prognosis. Among the new technologies, quantitative phase imaging (QPI) has demonstrated promise for histopathology…

Recently, a method of recording holograms of coherently illuminated three-dimensional scene without two-wave interference was demonstrated. The method is an extension of the coded aperture correlation holography from incoherent to coherent…

Optics · Physics 2023-07-19 Nathaniel Hai , Joseph Rosen

This article presents a thorough comparison of themain QPM techniques, focusing on their accuracy in terms of measurement precision and trueness. We focus on 8 techniques, namely digital holographic microscopy (DHM), cross-grating wavefront…

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