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We present a minimally-invasive endoscope based on a multimode fiber that combines photoacoustic and fluorescence sensing. From the measurement of a transmission matrix during a prior calibration step, a focused spot is produced and…

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Quantum imaging is an advanced method for microscopy or investigating the optical properties of materials or bio-medical inspections with high accuracy, low noise, and extremely low photo-damage. In previous work, we proposed a quantum…

Optics · Physics 2025-05-09 Mousume Samad , Maki Shimizu , Yasuto Hijikata

X-ray near field holography has proven to be a powerful 2D and 3D imaging technique with applications ranging from biomedical research to material sciences. To reconstruct meaningful and quantitative images from the measurement intensities,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-04 Jens Lucht , Leon M. Lohse , Thorsten Hohage , Tim Salditt

Confocal and multi-photon microscopy are widely used for in-vivo fluorescence imaging of biological tissues such as the brain, offering non-invasive access up to ~1 mm depth without major loss in performance. A recently-developed…

We report Tensorial Tomographic Differential Phase-Contrast microscopy (T2DPC), a quantitative label-free tomographic imaging method for simultaneous measurement of phase and anisotropy. T2DPC extends differential phase-contrast microscopy,…

We present an overview of the performances of a plenoptic microscope which combines the high sensitivity of a laser optical feedback imaging setup , the high resolution of optical synthetic aperture and a shot noise limited signal to noise…

Optics · Physics 2015-06-19 W Glastre , O Hugon , O Jacquin , H Guillet de Chatellus , E Lacot

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

Optics · Physics 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Quantum state tomography is an essential component of modern quantum technology. In application to continuous-variable harmonic-oscilator systems, such as the electromagnetic field, existing tomography methods typically reconstruct the…

Quantum Physics · Physics 2023-01-09 Ekaterina Fedotova , Nikolai Kuznetsov , Egor Tiunov , A. E. Ulanov , A. I. Lvovsky

Most methods tackling the phase retrieval problem of magnitude-only antenna measurements suffer from unrealistic sampling requirements, from unfeasible computational complexities, and, most severely, from the lacking reliability of…

Signal Processing · Electrical Eng. & Systems 2022-02-01 Alexander Paulus , Josef Knapp , Jonas Kornprobst , Thomas F. Eibert

The visualization of pure phase objects by wavefront sensing has important applications ranging from surface profiling to biomedical microscopy, and generally requires bulky and complicated setups involving optical spatial filtering,…

Optics · Physics 2023-08-29 Jianing Liu , Hao Wang , Yuyu Li , Lei Tian , Roberto Paiella

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

A novel phase retrieval algorithm for broadband hyperspectral phase imaging from noisy intensity observations is proposed. It utilizes advantages of the Fourier Transform spectroscopy in the self-referencing optical setup and provides,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Igor Shevkunov , Vladimir Katkovnik , Karen Egiazarian

Biofilm is a formation of microbial material on tooth substrata. Several methods to quantify dental biofilm coverage have recently been reported in the literature, but at best they provide a semi-automated approach to quantification with…

Computer Vision and Pattern Recognition · Computer Science 2014-07-11 Awais Mansoor , Valery Patsekin , Dale Scherl , J. Paul Robinson , Bartlomiej Rajwa

Raman spectroscopy is a label-free, chemically specific optical technique which provides detailed information about the chemical composition and structure of the excited analyte. Because of this, there is growing research interest in…

We use a coherent fiber bundle to demonstrate the endoscopic absorption imaging of quantum gases. We show that the fiber bundle introduces spurious noise in the picture mainly due to the strong core-to-core coupling. By direct comparison…

Quantum Gases · Physics 2020-02-03 Daniel Benedicto-Orenes , Anna Kowalczyk , Kai Bongs , Giovanni Barontini

We consider the general problem of estimating an unknown control parameter of an open quantum system. We establish a direct relation between the evolution of both system and environment and the precision with which the parameter can be…

Quantum Physics · Physics 2016-02-10 Katarzyna Macieszczak , Madalin Guta , Igor Lesanovsky , Juan P. Garrahan

In this study, we explore the theoretical application of entangled multi-mode squeezed light for label-free optical super-resolution imaging. By generating massively entangled multi-mode squeezed light through an array of balanced beam…

Quantum Physics · Physics 2023-03-30 Daniel Soh , Eric Chatterjee

We present a novel fiber-optic component, a "tapered multi-core fiber (MCF)", designed for integration into ultra-miniaturized endoscopes for minimally invasive two-photon point-scanning imaging and to address the power delivery issue that…

In this paper, we propose a nonlinear interferometer with feedback loops and explore its efficiency for phase estimation. We analyse two feedback schemes, one where both modes of the interferometer are fed-back into the device and another…

Quantum Physics · Physics 2025-07-24 Shivani Singh , Craig S. Hamilton , Igor Jex
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