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Photoacoustic (PA) imaging systems are spreading in the biomedical community, and the de-velopment of new PA contrast agents is an active area of research. However, PA contrast agents are usually characterized with spectrophotometry or…

Instrumentation and Detectors · Physics 2022-09-07 Théotim Lucas , Mitradeep Sarkar , Yoann Atlas , Clément Linger , Gilles Renault , Florence Gazeau , Jérôme Gateau

Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…

Medical Physics · Physics 2025-10-30 Talia Xu , Caitlin Smith , Charles Lo , Jami Shepherd , Gijs van Soest , Marco Zuniga

Photoacoustic microscopy (PAM) is a novel implementation of photoacoustic imaging (PAI) for visualizing the 3D bio-structure, which is realized by raster scanning of the tissue. However, as three involved critical imaging parameters,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhengyuan Zhang , Haoran Jin , Zesheng Zheng , Wenwen Zhang , Wenhao Lu , Feng Qin , Arunima Sharma , Manojit Pramanik , Yuanjin Zheng

Dynamic Photoacoustic Computed Tomography (PACT) is an important imaging technique for monitoring physiological processes, capable of providing high-contrast images of optical absorption at much greater depths than traditional optical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Youshen Xiao , Yiling Shi , Ruixi Sun , Hongjiang Wei , Fei Gao , Yuyao Zhang

Standard photoacoustic tomography (PAT) provides data that consist of time-dependent signals governed by the wave equation, which are measured on an observation surface. In contrast, the measured data from the recently invented full-field…

Numerical Analysis · Mathematics 2024-06-10 Ngoc Do , Markus Haltmeier , Richard Kowar , Linh V. Nguyen , Robert Nuster

Photo-Acoustic Tomography (PAT) can reconstruct a distribution of optical absorbers acting as instantaneous sound sources in subcutaneous microvasculature of a human breast. Adjoint methods for PAT, typically Time-Reversal (TR) and…

Numerical Analysis · Mathematics 2018-06-25 Hongxiang Lin , Takashi Azuma , Mehmet Burcin Unlu , Shu Takagi

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Photoacoustic microscopy (PAM) is a promising imaging modality because it is able to reveal optical absorption contrast in high resolution on the order of a micrometer. It can be applied in an endoscopic approach by implementing PAM into a…

Medical Physics · Physics 2019-11-22 Zhendong Guo , Zhanhong Ye , Weihao Shao , Lili Jing , Sung-Liang Chen

Quantitative Photoacoustic tomography (QPAT) is an emerging medical imaging modality which offers the possibility of combining the high resolution of the acoustic waves and large contrast of optical waves by quantifying the molecular…

Numerical Analysis · Mathematics 2014-10-30 Adriano De Cezaro , Fabiana Travessini De Cezaro

Quantitative photoacoustic tomography (QPAT) is a recent hybrid imaging modality that couples optical tomography with ultrasound imaging to achieve high resolution imaging of optical properties of scattering media. Image reconstruction in…

Analysis of PDEs · Mathematics 2015-09-02 Tian Ding , Kui Ren , Sarah Vallelian

Significance: We proposed a new design of hand-held linear-array photoacoustic (PA) probe which can acquire multi images via motor moving. Moreover, images from different locations are utilized via imaging fusion for SNR enhancement. Aim:…

Medical Physics · Physics 2020-11-09 Yongjian Zhao , Luyao Zhu , Hengrong Lan , Daohuai Jiang , Feng Gao , Fei Gao

Spherical matrix arrays arguably represent an advantageous tomographic detection geometry for non-invasive deep tissue mapping of vascular networks and oxygenation with volumetric optoacoustic tomography (VOT). Hybridization of VOT with…

Medical Physics · Physics 2021-01-05 Justine Robin , Ali Ozbek , Michael Reiss , Xose-Luis Dean-Ben , Daniel Razansky

Real-time transrectal ultrasound (TRUS) image guidance during robot-assisted laparoscopic radical prostatectomy has the potential to enhance surgery outcomes. Whether conventional or photoacoustic TRUS is used, the robotic system and the…

Robotics · Computer Science 2023-07-21 Zijian Wu , Hamid Moradi , Shuojue Yang , Hyunwoo Song , Emad M. Boctor , Septimiu E. Salcudean

A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…

Numerical Analysis · Mathematics 2020-09-07 Felix Lucka , Nam Huynh , Marta Betcke , Edward Zhang , Paul Beard , Ben Cox , Simon Arridge

Photoacoustic tomography (PAT) offers optical contrast, whereas magnetic resonance imaging (MRI) excels in imaging soft tissue and organ anatomy. The fusion of PAT with MRI holds promising application prospects due to their complementary…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yutian Zhong , Jinchuan He , Zhichao Liang , Shuangyang Zhang , Qianjin Feng , Lijun Lu , Li Qi

Photoacoustic tomography (PAT) is an emerging imaging modality that combines the complementary strengths of optical contrast and ultrasonic resolution. A central task is image reconstruction, where measured acoustic signals are used to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Markus Haltmeier , Nadja Gruber , Gyeongha Hwang

Ultrasound Tomography has seen a revival of interest in the past decade, especially for breast imaging, due to improvements in both ultrasound and computing hardware. In particular, three-dimensional ultrasound tomography, a fully…

Computational Physics · Physics 2020-05-27 Ashkan Javaherian , Felix Lucka , Ben Cox

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai