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Related papers: Omnisolver: an extensible interface to Ising spin …

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We present ensmallen, a fast and flexible C++ library for mathematical optimization of arbitrary user-supplied functions, which can be applied to many machine learning problems. Several types of optimizations are supported, including…

Mathematical Software · Computer Science 2018-12-11 Shikhar Bhardwaj , Ryan R. Curtin , Marcus Edel , Yannis Mentekidis , Conrad Sanderson

Optimizing the properties of molecules (materials or drugs) for stronger toughness, lower toxicity, or better bioavailability has been a long-standing challenge. In this context, we propose a molecular optimization framework called Q-Drug…

Quantum Physics · Physics 2023-08-28 Zhaoping Xiong , Xiaopeng Cui , Xinyuan Lin , Feixiao Ren , Bowen Liu , Yunting Li , Manhong Yung , Nan Qiao

An Ising model is defined by a quadratic objective function known as the Hamiltonian, composed of spin variables that can take values of either $-1$ or $+1$. The goal is to assign spin values to these variables in a way that minimizes the…

Emerging Technologies · Computer Science 2024-06-27 Shunsuke Tsukiyama , Koji Nakano , Xiaotian Li , Yasuaki Ito , Takumi Kato , Yuya Kawamata

Modeling composite systems of spins or electrons coupled to bosonic modes is of significant interest for many fields of applied quantum physics and chemistry. A quantum simulation can allow for the solution of quantum problems beyond…

Quantum and quantum-inspired optimisation algorithms are designed to solve problems represented in binary, quadratic and unconstrained form. Combinatorial optimisation problems are therefore often formulated as Quadratic Unconstrained…

Artificial Intelligence · Computer Science 2022-05-27 Mayowa Ayodele , Richard Allmendinger , Manuel López-Ibáñez , Matthieu Parizy

Test optimization contains test case selection and minimization, which is an important challenge in software testing and has been addressed with search-based approaches intensively in the past. Inspired by the recent advancement of using…

Software Engineering · Computer Science 2026-04-14 Yige Yang , Man Zhang , Tao Yue

The integration of large language models (LLMs) into materials science offers a transformative opportunity to streamline computational workflows, yet current agentic systems remain constrained by rigid, carefully crafted domain-specific…

Materials Science · Physics 2026-04-08 Fengxu Yang , Jack D. Evans

We propose a novel method for reducing the number of variables in quadratic unconstrained binary optimization problems, using a quantum annealer (or any sampler) to fix the value of a large portion of the variables to values that have a…

Quantum Physics · Physics 2017-09-26 Hamed Karimi , Gili Rosenberg

Quadratic unconstrained binary optimization (QUBO) is a field of operations research that is attracting growing interest due to the recent availability of quantum hardware targeted at solving QUBO problems. However, practical adoption is…

Software Engineering · Computer Science 2026-01-22 Lodovica Marchesi , Amal Nasharti , Michele Marchesi

Binary optimization is a powerful tool for modeling combinatorial problems, yet scalable and theoretically sound solution methods remain elusive. Conventional solvers often rely on heuristic strategies with weak guarantees or struggle with…

Optimization and Control · Mathematics 2026-05-12 Wenbo Liu , Akang Wang , Dun Ma , Hongyi Jiang , Jianghua Wu , Wenguo Yang

We present the design of a flexible quantum-chemical method development framework, which supports employing any type of basis function. This design has been implemented in the light-weight program package molsturm, yielding a…

Chemical Physics · Physics 2018-11-15 Michael F. Herbst , Andreas Dreuw , James Emil Avery

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

As we rapidly approach the frontiers of ultra large computing resources, software optimization is becoming of paramount interest to scientific application developers interested in efficiently leveraging all available on-Node computing…

We propose a mixed-integer quadratic programming (QP) solver that is suitable for use in embedded applications, for example, hybrid model predictive control (MPC). The solver is based on the branch-and-bound method, and uses a recently…

Optimization and Control · Mathematics 2022-11-24 Daniel Arnström , Daniel Axehill

We present the bilateral solver, a novel algorithm for edge-aware smoothing that combines the flexibility and speed of simple filtering approaches with the accuracy of domain-specific optimization algorithms. Our technique is capable of…

Computer Vision and Pattern Recognition · Computer Science 2016-07-25 Jonathan T. Barron , Ben Poole

We describe a framework for reformulating and solving optimization problems that generalizes the well-known framework originally introduced by Benders. We discuss details of the application of the procedures to several classes of…

Optimization and Control · Mathematics 2023-07-14 Suresh Bolusani , Ted K. Ralphs

We present a quantum solver for partial differential equations based on a flexible matrix product operator representation. Utilizing mid-circuit measurements and a state-dependent norm correction, this scheme overcomes the restriction of…

Quantum Physics · Physics 2026-04-22 Pia Siegl , Greta Sophie Reese , Tomohiro Hashizume , Nis-Luca van Hülst , Dieter Jaksch

Quantum computing has the potential to surpass the capabilities of current classical computers when solving complex problems. Combinatorial optimization has emerged as one of the key target areas for quantum computers as problems found in…

Quantum Physics · Physics 2023-07-27 Juan Giraldo , José Ossorio , Norha M. Villegas , Gabriel Tamura , Ulrike Stege

Quadratic Unconstrained Binary Optimization (QUBO) is a broad class of optimization problems with many practical applications. To solve its hard instances in an exact way, known classical algorithms require exponential time and several…

Quantum Physics · Physics 2021-01-21 Gian Giacomo Guerreschi

Quantum annealers offer a promising approach to solve Quadratic Unconstrained Binary Optimization (QUBO) problems, which have a wide range of applications. However, when a user submits its QUBO problem to a third-party quantum annealer, the…

Cryptography and Security · Computer Science 2024-09-30 Moyang Xie , Yuan Zhang , Sheng Zhong , Qun Li
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