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In this note, we describe an experiment on portfolio optimization using the Quadratic Unconstrained Binary Optimization (QUBO) formulation. The dataset we use is taken from a real-world problem for which a classical solution is currently…

The family of Multiscale Hybrid-Mixed (MHM) finite element methods has received considerable attention from the mathematics and engineering community in the last few years. The MHM methods allow solving highly heterogeneous problems on…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-03-31 Antonio Tadeu A. Gomes , Weslley S. Pereira , Frederic Valentin , Diego Paredes

We present the SLIM (https://github.com/slimgroup) open-source software framework for computational geophysics, and more generally, inverse problems based on the wave-equation (e.g., medical ultrasound). We developed a software environment…

Mixed discrete-continuous optimization is central to engineering design, where discrete choices interact with continuous fields. These problems are difficult due to high-dimensional, complex search spaces. To tackle them, Quantum Annealing…

Computational Engineering, Finance, and Science · Computer Science 2026-03-19 Fabian Key , Lukas Freinberger , Mayu Muramatsu , Norbert Hosters

Recent technological developments in the field of experimental quantum annealing have made prototypical annealing optimizers with hundreds of qubits commercially available. The experimental demonstration of a quantum speedup for…

Quantum Physics · Physics 2016-07-15 Jeffrey Marshall , Victor Martin-Mayor , Itay Hen

Real world combinatorial optimization problems such as scheduling are typically too complex to solve with exact methods. Additionally, the problems often have to observe vaguely specified constraints of different importance, the available…

Artificial Intelligence · Computer Science 2007-05-23 Andreas Raggl , Wolfgang Slany

A standard quadratic program is an optimization problem that consists of minimizing a (nonconvex) quadratic form over the unit simplex. We focus on reformulating a standard quadratic program as a mixed integer linear programming problem. We…

Optimization and Control · Mathematics 2018-10-05 Jacek Gondzio , E. Alper Yildirim

This paper presents a novel design update strategy for topology optimization, as an iterative optimization. The key contribution lies in incorporating a design updater concept with quantum annealing, applicable to both truss and continuum…

Computational Engineering, Finance, and Science · Computer Science 2025-01-24 Naruethep Sukulthanasorn , Junsen Xiao , Koya Wagatsuma , Reika Nomura , Shuji Moriguchi , Kenjiro Terada

In this proceedings we describe the current development status and recent technical achievements of Qibo, an open-source framework for quantum simulation. After a concise overview of the project goal, we introduce the modular layout for…

Quantum Physics · Physics 2023-03-01 Stefano Carrazza , Stavros Efthymiou , Marco Lazzarin , Andrea Pasquale

We propose a general learning algorithm for solving optimization problems, based on a simple strategy of trial and adaptation. The algorithm maintains a probability distribution of possible solutions (configurations), which is updated…

adap-org · Physics 2009-10-30 Kan Chen

In this paper, we extend a previously presented Grover-based heuristic to tackle general combinatorial optimization problems with linear constraints. We further describe the introduced method as a framework that enables performance…

Quantum Physics · Physics 2025-12-08 Sören Wilkening , Timo Ziegler , Maximilian Hess

Quantum computing has made tremendous improvements in both software and hardware that have sparked interest in academia and industry to realize quantum computing applications. To this end, several steps are necessary: The underlying problem…

We propose a quantum-classical hybrid method for solving large-scale mixed-integer quadratic problems (MIQP). Although extended Benders decomposition is effective for MIQP, its master problem which handles the integer and quadratic…

Quantum Physics · Physics 2026-02-19 Takuma Yoshihara , Masayuki Ohzeki

We introduce an adaptable and modular hybrid architecture designed for fault-tolerant quantum computing. It combines quantum emitters and linear-optical entangling gates to leverage the strength of both matter-based and photonic-based…

A multi-scale framework was recently proposed for more realistic molecular dynamics simulations in continuum solvent models by coupling a molecular mechanics treatment of solute with a fluid mechanics treatment of solvent, where we…

Biological Physics · Physics 2018-01-17 Li Xiao , Ray Luo

Recent studies on quantum computing algorithms focus on excavating features of quantum computers which have potential for contributing to computational model enhancements. Among various approaches, quantum annealing methods effectively…

Quantum Physics · Physics 2021-11-02 Sun Woo Park , Hyunju Lee , Byung Chun Kim , Youngho Woo , Kyungtaek Jun

The availability of quantum hardware via the cloud offers opportunities for new approaches to computing optimization problems in an industrial environment. However, selecting the right quantum hardware is difficult for non-experts due to…

Quantum Physics · Physics 2025-09-17 Djamel Laps-Bouraba , Markus Zajac , Uta Störl

The development of advanced quantum-classical algorithms is among the most prominent strategies in quantum computing. Numerous hybrid solvers have been introduced recently. Many of these methods are created ad hoc to address specific use…

Emerging Technologies · Computer Science 2024-12-05 Eneko Osaba , Pablo Miranda-Rodriguez

Nonlinear boolean equation systems play an important role in a wide range of applications. Grover's algorithm is one of the best-known quantum search algorithms in solving the nonlinear boolean equation system on quantum computers. In this…

Quantum Physics · Physics 2024-10-16 Xiang Li , Hanxiang Shen , Weiguo Gao , Yingzhou Li

Cardinality-constrained binary optimization is a fundamental computational primitive with broad applications in machine learning, finance, and scientific computing. In this work, we introduce a Grover-based quantum algorithm that exploits…

Quantum Physics · Physics 2026-03-17 Haomu Yuan , Hanqing Wu , Kuan-Cheng Chen , Bin Cheng , Crispin H. W. Barnes
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