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Related papers: Optofluidic ptychography on a chip

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In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…

Advances in fluorescence microscopy have reached a plateau in improving depth-to-resolution ratios for imaging scattering tissues, highlighting an urgent need for innovative techniques. We introduce Wavelens, a groundbreaking opaque lens…

Ultrasound is a key technology in healthcare, and it is being explored for non-invasive, wearable, continuous monitoring of vital signs. However, its widespread adoption in this scenario is still hindered by the size, complexity, and power…

Operation of nanomechanical devices in water environment has been challenging due to the strong viscous damping that greatly impedes the mechanical motion. Here we demonstrate an optomechanical micro-wheel resonator integrated in…

Optics · Physics 2015-08-12 King Yan Fong , Menno Poot , Hong X. Tang

A micro-ring-resonator (MRR) optical biosensor based on the evanescent field sensing mechanism has been extensively studied due to its high sensitivity and compact device size. However, a suitable on-chip integrated spectrometer device has…

Optics · Physics 2022-07-19 Kyoung Min Yoo , May Hlaing , Sourabh Jain , James Fan , Yue An , Ray T. Chen

The combination of different imaging modalities into single imaging platforms has a strong potential in biomedical sciences since it permits the analysis of complementary properties of the target sample. Here, we report on an extremely…

Optics · Physics 2025-01-17 David Alonso , Javier Garcia , Vicente Mico

Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Kyrollos Yanny , Nick Antipa , William Liberti , Sam Dehaeck , Kristina Monakhova , Fanglin Linda Liu , Konlin Shen , Ren Ng , Laura Waller

Microplastics are increasingly recognized as a global environmental health threat, yet their detection and characterization remain constrained by the cost, form factor, and throughput of existing analytical tools. Portable…

Applied Physics · Physics 2025-10-31 Sayedus Salehin , Syed Shaheer Uddin Ahmed , Uzay Tefek , Laura Weirauch , M. Selim Hanay

Microscopy is an essential tool in scientific research, enabling the visualization of structures at micro- and nanoscale resolutions. However, the field of microscopy often encounters limitations in field-of-view (FOV), restricting the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Huanhuan Zhao , Ruben Millan-Solsona , Marti Checa , Spenser R. Brown , Jennifer L. Morrell-Falvey , Liam Collins , Arpan Biswas

As a burgeoning technique, out-of-focus electron ptychography offers the potential for rapidly imaging atomic-scale large fields of view (FoV) using a single diffraction dataset. However, achieving robust out-of-focus ptychographic…

On-chip cavity optomechanics, in which strong co-localization of light and mechanical motion is engineered, relies on efficient coupling of light both into and out of the on-chip optical resonator. Here we detail our particular style of…

Mesoscale and Nanoscale Physics · Physics 2014-05-19 Bradley D Hauer , Paul H Kim , Callum Doolin , Allison JR MacDonald , Hugh Ramp , John P Davis

Islet microencapsulation is a promising solution to diabetes treatment, but its quality control based on manual microscopic inspection is extremely low-throughput, highly variable and laborious. This study presents a high-throughput…

Instrumentation and Detectors · Physics 2018-12-31 Yibo Zhang , Michael Alexander , Sam Yang , Yinxu Bian , Elliot Botvinick , Jonathan R. T. Lakey , Aydogan Ozcan

Integrated polarimetric receivers have the potential to define a new generation of lightweight, high-performance instrumentation for remote sensing. To date, on-chip polarization-selective devices such as polarizing beam-splitters have yet…

Optics · Physics 2017-02-21 Jeff Chiles , Tracy Sjaardema , Ashutosh Rao , Sasan Fathpour

In this work, we present and investigate the novel blind inverse problem of position-blind ptychography, i.e., ptychographic phase retrieval without any knowledge of scan positions, which then must be recovered jointly with the image. The…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Simon Welker , Lorenz Kuger , Tim Roith , Berthy Feng , Martin Burger , Timo Gerkmann , Henry Chapman

A seamless chip-to-world photonic interface enables wide-ranging advancements in optical ranging, display, communication, computation, imaging, and light-matter interaction. An optimal solution allows for 2D scanning of a…

X-ray ptychography imaging at synchrotron facilities like the Advanced Photon Source (APS) involves controlling instrument hardwares to collect a set of diffraction patterns from overlapping coherent illumination spots on extended samples,…

Instrumentation and Detectors · Physics 2022-02-10 Ke Yue , Junjing Deng , Yi Jiang , Youssef Nashed , David Vine , Stefan Vogt

Ptychography is a well-established coherent diffraction imaging technique that enables non-invasive imaging of samples at a nanometer scale. It has been extensively used in various areas such as the defense industry or materials science.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Semih Barutcu , Doğa Gürsoy , Aggelos K. Katsaggelos

Limited access to corrective eyewear remains a significant medical, societal, and economic challenge, even in the 21st century. More than 1 billion people suffer from uncorrected vision impairment, with the vast majority residing in…

Applied Physics · Physics 2024-06-17 Mor Elgarisi , Omer Luria , Yotam Katzman , Daniel Widerker , Valeri Frumkin , Moran Bercovici

There is a clear need for developments in characterisation techniques that provide detailed information about structure-function relationships in biology. Using electron microscopy to achieve high resolution while maintaining a broad field…

Quantitative Methods · Quantitative Biology 2023-09-12 Chen Huang , Judy S. Kim , Angus I. Kirkland

On-chip photonic processors for neural networks have potential benefits in both speed and energy efficiency but have not yet reached the scale at which they can outperform electronic processors. The dominant paradigm for designing on-chip…

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