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We present the development of an optically detected magnetic resonance (ODMR) system, which enables us to perform the ODMR measurements of a single defect in solids at high frequencies and high magnetic fields. Using the high-frequency and…

Mesoscale and Nanoscale Physics · Physics 2015-02-12 Viktor Stepanov , Franklin H. Cho , Chathuranga Abeywardana , Susumu Takahashi

Analyzing the kinetics of biological processes plays a significant role in understanding fundamental cellular functions. Many physics-based technologies used to study such processes are limited by the shot noise inherent to the coherent…

Quantum Physics · Physics 2025-04-16 Mrunal Kamble , Evan Humberd , Tian Li , Girish S. Agarwal

Decoding human activity accurately from wearable sensors can aid in applications related to healthcare and context awareness. The present approaches in this domain use recurrent and/or convolutional models to capture the spatio-temporal…

Human-Computer Interaction · Computer Science 2020-12-21 Satya P. Singh , Aimé Lay-Ekuakille , Deepak Gangwar , Madan Kumar Sharma , Sukrit Gupta

The local thermal conductivity (\k{appa}) is a pivotal biophysical parameter, governing intracellular heat flux and underlying functional processes like metabolic regulation and stress response. However, label-free mapping with sub-micron…

Biological Physics · Physics 2026-03-04 Jiahua Zhang , Yong Hou , Xinhao Hu , Yicheng Wang , Madoka Suzuki , Bo Gao , Zhiqin Chu

The constant interplay and information exchange between cells and their micro-environment are essential to their survival and ability to execute biological functions. To date, a few leading technologies such as traction force microscopy,…

Cell Behavior · Quantitative Biology 2023-06-29 Feng Xu , Shuxiang Zhang , Linjie Ma , Yong Hou , Jie Li , Andrej Denisenko , Zifu Li , Joachim Spatz , Jörg Wrachtrup , Qiang Wei , Zhiqin Chu

The detection of photocurrents is central to understanding and harnessing the interaction of light with matter. Although widely used, transport-based detection averages over spatial distributions and can suffer from low photocarrier…

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

Methodology · Statistics 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

Small vibrations observed in video can unveil information beyond what is visual, such as sound and material properties. It is possible to passively record these vibrations when they are visually perceptible, or actively amplify their visual…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Mingxuan Cai , Dekel Galor , Amit Pal Singh Kohli , Jacob L. Yates , Laura Waller

We propose a new type of sensor, which uses diamond containing the optically active nitrogen-vacancy (NV$^-$) centres as a laser medium. The magnetometer can be operated at room-temperature and generates light that can be readily fibre…

Quantum Physics · Physics 2016-01-12 Jan Jeske , Jared H. Cole , Andrew D. Greentree

Experimental noise often contains valuable information on the interactions of a system with its environment but establishing a relation between the measured time fluctuations and relevant physical observables is rarely apparent. Here, we…

Quantum Physics · Physics 2024-01-17 Tom Delord , Richard Monge , Carlos A. Meriles

Nitrogen-vacancy (NV) centers in nanodiamonds have emerged as a promising quantum sensing platform for biomedical imaging applications, yet random orientations of individual particles present significant challenges in large-scale sensor…

Quantum Physics · Physics 2025-07-09 Yizhou Wang , Haochen Shen , Zhongyuan Liu , Yue Yu , Shengwang Du , Chong Zu , Chuanwei Zhang

We introduce a system that recognizes concurrent activities from real-world data captured by multiple sensors of different types. The recognition is achieved in two steps. First, we extract spatial and temporal features from the multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-02-07 Xinyu Li , Yanyi Zhang , Jianyu Zhang , Shuhong Chen , Ivan Marsic , Richard A. Farneth , Randall S. Burd

Real-time temperature monitoring inside living organisms provides a direct measure of their biological activities, such as homeostatic thermoregulation and energy metabolism. However, it is challenging to reduce the size of bio-compatible…

Nitrogen-doped ultrananocrystalline diamond (N-UNCD) is a promising material for a variety of neural interfacing applications, due to its unique combination of high conductivity, bioinertness, and durability. One emerging application for…

Motion estimation is a fundamental step in dynamic medical image processing for the assessment of target organ anatomy and function. However, existing image-based motion estimation methods, which optimize the motion field by evaluating the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Yuyu Guo , Lei Bi , Dongming Wei , Liyun Chen , Zhengbin Zhu , Dagan Feng , Ruiyan Zhang , Qian Wang , Jinman Kim

We present a sensitive diamond quantum sensor with a magnetic field sensitivity of $9.4 \pm 0.1~\mathrm{pT/\sqrt{Hz}}$ in a near-dc frequency range of 5 to 100~Hz. This sensor is based on the continuous-wave optically detected magnetic…

Living systems process sensory data to facilitate adaptive behaviour. A given sensor can be stimulated as the result of internally driven activity, or by purely external (environmental) sources. It is clear that these inputs are processed…

Neural and Evolutionary Computing · Computer Science 2022-05-16 James Garner , Matthew Egbert

A realization of the force-induced remnant magnetization spectroscopy (FIRMS) technique of specific biomolecular binding is presented where detection is accomplished with wide-field optical and diamond-based magnetometry using an ensemble…

Instrumentation and Detectors · Physics 2020-01-08 Sean Lourette , Lykourgos Bougas , Metin Kayci , Shoujun Xu , Dmitry Budker

Random lasers are highly configurable light sources that are promising for imaging and photonic integration. In this study, random lasing action was generated by optically pumping MBBA liquid crystals infiltrated with gold nanoparticles and…

Optics · Physics 2023-05-02 Yiyang Zhi , Andrew Lininger , Giuseppe Strangi

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson