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Knowledge graphs (KGs) are an important tool for representing complex relationships between entities in the biomedical domain. Several methods have been proposed for learning embeddings that can be used to predict new links in such graphs.…

Artificial Intelligence · Computer Science 2026-05-12 Daniel Daza , Dimitrios Alivanistos , Payal Mitra , Thom Pijnenburg , Michael Cochez , Paul Groth

Ontology-based approaches for predicting gene-disease associations include the more classical semantic similarity methods and more recently knowledge graph embeddings. While semantic similarity is typically restricted to hierarchical…

Machine Learning · Computer Science 2021-06-01 Susana Nunes , Rita T. Sousa , Catia Pesquita

In the last decades, people have been consuming and combining more drugs than before, increasing the number of Drug-Drug Interactions (DDIs). To predict unknown DDIs, recently, studies started incorporating Knowledge Graphs (KGs) since they…

Artificial Intelligence · Computer Science 2023-08-14 Lizzy Farrugia , Lilian M. Azzopardi , Jeremy Debattista , Charlie Abela

Knowledge Graph (KG) alignment is to discover the mappings (i.e., equivalent entities, relations, and others) between two KGs. The existing methods can be divided into the embedding-based models, and the conventional reasoning and lexical…

Computation and Language · Computer Science 2021-06-14 Zhiyuan Qi , Ziheng Zhang , Jiaoyan Chen , Xi Chen , Yuejia Xiang , Ningyu Zhang , Yefeng Zheng

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

Machine Learning · Computer Science 2024-04-24 Rita T. Sousa , Heiko Paulheim

Feature selection in Knowledge Graphs (KGs) are increasingly utilized in diverse domains, including biomedical research, Natural Language Processing (NLP), and personalized recommendation systems. This paper delves into the methodologies…

Machine Learning · Computer Science 2024-06-24 Sisi Shao , Pedro Henrique Ribeiro , Christina Ramirez , Jason H. Moore

Knowledge graph embedding (KGE) is an increasingly popular technique that aims to represent entities and relations of knowledge graphs into low-dimensional semantic spaces for a wide spectrum of applications such as link prediction,…

Machine Learning · Computer Science 2023-10-17 Jiahang Cao , Jinyuan Fang , Zaiqiao Meng , Shangsong Liang

Knowledge Graph Embeddings (KGEs) have shown promising performance on link prediction tasks by mapping the entities and relations from a knowledge graph into a geometric space (usually a vector space). Ultimately, the plausibility of the…

Machine Learning · Computer Science 2020-10-20 Mojtaba Nayyeri , Chengjin Xu , Jens Lehmann , Sahar Vahdati

Conventional Knowledge Graph Completion (KGC) assumes that all test entities appear during training. However, in real-world scenarios, Knowledge Graphs (KG) evolve fast with out-of-knowledge-graph (OOKG) entities added frequently, and we…

Computation and Language · Computer Science 2020-09-29 Damai Dai , Hua Zheng , Fuli Luo , Pengcheng Yang , Baobao Chang , Zhifang Sui

While Knowledge Graphs (KGs) have become increasingly popular across various scientific disciplines for their ability to model and interlink huge quantities of data, essentially all real-world KGs are known to be incomplete. As such, with…

Machine Learning · Computer Science 2025-05-09 Jeffrey Seathrún Sardina

Knowledge Graphs (KGs) store human knowledge in the form of entities (nodes) and relations, and are used extensively in various applications. KG embeddings are an effective approach to addressing tasks like knowledge discovery, link…

Artificial Intelligence · Computer Science 2025-02-03 Ioannis Reklos , Jacopo de Berardinis , Elena Simperl , Albert Meroño-Peñuela

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

Integrating structured knowledge from Knowledge Graphs (KGs) into Large Language Models (LLMs) remains a key challenge for symbolic reasoning. Existing methods mainly rely on prompt engineering or fine-tuning, which lose structural fidelity…

Machine Learning · Computer Science 2025-05-13 Erica Coppolillo

The incompleteness of Knowledge Graphs (KGs) is a crucial issue affecting the quality of AI-based services. In the scholarly domain, KGs describing research publications typically lack important information, hindering our ability to analyse…

Learning embeddings of entities and relations existing in knowledge bases allows the discovery of hidden patterns in data. In this work, we examine the geometrical space's contribution to the task of knowledge base completion. We focus on…

Computation and Language · Computer Science 2019-08-20 Prodromos Kolyvakis , Alexandros Kalousis , Dimitris Kiritsis

Knowledge Graphs (KGs) are composed of structured information about a particular domain in the form of entities and relations. In addition to the structured information KGs help in facilitating interconnectivity and interoperability between…

Artificial Intelligence · Computer Science 2020-05-15 Genet Asefa Gesese , Russa Biswas , Mehwish Alam , Harald Sack

We study the problem of explaining link predictions in the Knowledge Graph Embedding (KGE) models. We propose an example-based approach that exploits the latent space representation of nodes and edges in a knowledge graph to explain…

Machine Learning · Computer Science 2022-12-07 Adrianna Janik , Luca Costabello

Knowledge graphs (KGs) have become valuable knowledge resources in various applications, and knowledge graph embedding (KGE) methods have garnered increasing attention in recent years. However, conventional KGE methods still face challenges…

Computation and Language · Computer Science 2023-12-19 Mingyang Chen , Wen Zhang , Yuxia Geng , Zezhong Xu , Jeff Z. Pan , Huajun Chen

Biomedical knowledge graphs (KG) are heterogenous networks consisting of biological entities as nodes and relations between them as edges. These entities and relations are extracted from millions of research papers and unified in a single…

Artificial Intelligence · Computer Science 2022-11-11 Dattaraj J. Rao , Shraddha S. Mane , Mukta A. Paliwal

Knowledge-intensive tasks pose a significant challenge for Machine Learning (ML) techniques. Commonly adopted methods, such as Large Language Models (LLMs), often exhibit limitations when applied to such tasks. Nevertheless, there have been…

Machine Learning · Computer Science 2024-05-20 Albert Sawczyn , Jakub Binkowski , Piotr Bielak , Tomasz Kajdanowicz